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Celecoxib inactivates epithelial-mesenchymal transition stimulated by hypoxia and/or epidermal growth factor in colon cancer cells.

Bocca C, Bozzo F, Cannito S, Parola M, Miglietta A.

Mol Carcinog. 2012 Oct;51(10):783-95. doi: 10.1002/mc.20846.


HDAC inhibitors induce epithelial-mesenchymal transition in colon carcinoma cells.

Ji M, Lee EJ, Kim KB, Kim Y, Sung R, Lee SJ, Kim DS, Park SM.

Oncol Rep. 2015 May;33(5):2299-308. doi: 10.3892/or.2015.3879.


Epithelial-mesenchymal transition associates with maintenance of stemness in spheroid-derived stem-like colon cancer cells.

Han XY, Wei B, Fang JF, Zhang S, Zhang FC, Zhang HB, Lan TY, Lu HQ, Wei HB.

PLoS One. 2013 Sep 9;8(9):e73341. doi: 10.1371/journal.pone.0073341.


Wnt3a expression is associated with epithelial-mesenchymal transition and promotes colon cancer progression.

Qi L, Sun B, Liu Z, Cheng R, Li Y, Zhao X.

J Exp Clin Cancer Res. 2014 Dec 11;33:107. doi: 10.1186/s13046-014-0107-4.


EGF signalling pathway regulates colon cancer stem cell proliferation and apoptosis.

Feng Y, Dai X, Li X, Wang H, Liu J, Zhang J, Du Y, Xia L.

Cell Prolif. 2012 Oct;45(5):413-9. doi: 10.1111/j.1365-2184.2012.00837.x.


CD44 enhances the epithelial-mesenchymal transition in association with colon cancer invasion.

Cho SH, Park YS, Kim HJ, Kim CH, Lim SW, Huh JW, Lee JH, Kim HR.

Int J Oncol. 2012 Jul;41(1):211-8. doi: 10.3892/ijo.2012.1453.


Dickkopf-1 inhibits epithelial-mesenchymal transition of colon cancer cells and contributes to colon cancer suppression.

Qi L, Sun B, Liu Z, Li H, Gao J, Leng X.

Cancer Sci. 2012 Apr;103(4):828-35. doi: 10.1111/j.1349-7006.2012.02222.x.


Isolation and characterization of calcium sensing receptor null cells: a highly malignant and drug resistant phenotype of colon cancer.

Singh N, Liu G, Chakrabarty S.

Int J Cancer. 2013 May 1;132(9):1996-2005. doi: 10.1002/ijc.27902.


Canonical Wnt signals combined with suppressed TGFβ/BMP pathways promote renewal of the native human colonic epithelium.

Reynolds A, Wharton N, Parris A, Mitchell E, Sobolewski A, Kam C, Bigwood L, El Hadi A, Münsterberg A, Lewis M, Speakman C, Stebbings W, Wharton R, Sargen K, Tighe R, Jamieson C, Hernon J, Kapur S, Oue N, Yasui W, Williams MR.

Gut. 2014 Apr;63(4):610-21. doi: 10.1136/gutjnl-2012-304067.


ALDH1B1 Is Crucial for Colon Tumorigenesis by Modulating Wnt/β-Catenin, Notch and PI3K/Akt Signaling Pathways.

Singh S, Arcaroli J, Chen Y, Thompson DC, Messersmith W, Jimeno A, Vasiliou V.

PLoS One. 2015 May 7;10(5):e0121648. doi: 10.1371/journal.pone.0121648.


Incomplete epithelial-mesenchymal transition in p16-positive squamous cell carcinoma cells correlates with β-catenin expression.

Umbreit C, Flanjak J, Weiss C, Erben P, Aderhold C, Faber A, Stern-Straeter J, Hoermann K, Schultz JD.

Anticancer Res. 2014 Dec;34(12):7061-9.


Ursodeoxycholic acid and F(6)-D(3) inhibit aberrant crypt proliferation in the rat azoxymethane model of colon cancer: roles of cyclin D1 and E-cadherin.

Wali RK, Khare S, Tretiakova M, Cohen G, Nguyen L, Hart J, Wang J, Wen M, Ramaswamy A, Joseph L, Sitrin M, Brasitus T, Bissonnette M.

Cancer Epidemiol Biomarkers Prev. 2002 Dec;11(12):1653-62.


OVOL2, an Inhibitor of WNT Signaling, Reduces Invasive Activities of Human and Mouse Cancer Cells and Is Down-regulated in Human Colorectal Tumors.

Ye GD, Sun GB, Jiao P, Chen C, Liu QF, Huang XL, Zhang R, Cai WY, Li SN, Wu JF, Liu YJ, Wu RS, Xie YY, Chan EC, Liou YC, Li BA.

Gastroenterology. 2016 Mar;150(3):659-671.e16. doi: 10.1053/j.gastro.2015.11.041.


KIT Signaling Promotes Growth of Colon Xenograft Tumors in Mice and Is Up-Regulated in a Subset of Human Colon Cancers.

Chen EC, Karl TA, Kalisky T, Gupta SK, O'Brien CA, Longacre TA, van de Rijn M, Quake SR, Clarke MF, Rothenberg ME.

Gastroenterology. 2015 Sep;149(3):705-17.e2. doi: 10.1053/j.gastro.2015.05.042.


Modulation of stemness in a human normal intestinal epithelial crypt cell line by activation of the WNT signaling pathway.

Guezguez A, Paré F, Benoit YD, Basora N, Beaulieu JF.

Exp Cell Res. 2014 Apr 1;322(2):355-64. doi: 10.1016/j.yexcr.2014.02.009.


Role of protein kinase C and epidermal growth factor receptor signalling in growth stimulation by neurotensin in colon carcinoma cells.

Müller KM, Tveteraas IH, Aasrum M, Ødegård J, Dawood M, Dajani O, Christoffersen T, Sandnes DL.

BMC Cancer. 2011 Oct 2;11:421. doi: 10.1186/1471-2407-11-421.


Stimulus-dependent differences in signalling regulate epithelial-mesenchymal plasticity and change the effects of drugs in breast cancer cell lines.

Cursons J, Leuchowius KJ, Waltham M, Tomaskovic-Crook E, Foroutan M, Bracken CP, Redfern A, Crampin EJ, Street I, Davis MJ, Thompson EW.

Cell Commun Signal. 2015 May 15;13:26. doi: 10.1186/s12964-015-0106-x.


Hypoxia-inducible factors modulate the stemness and malignancy of colon cancer cells by playing opposite roles in canonical Wnt signaling.

Santoyo-Ramos P, Likhatcheva M, García-Zepeda EA, Castañeda-Patlán MC, Robles-Flores M.

PLoS One. 2014 Nov 14;9(11):e112580. doi: 10.1371/journal.pone.0112580.


Dose-dependent roles for canonical Wnt signalling in de novo crypt formation and cell cycle properties of the colonic epithelium.

Hirata A, Utikal J, Yamashita S, Aoki H, Watanabe A, Yamamoto T, Okano H, Bardeesy N, Kunisada T, Ushijima T, Hara A, Jaenisch R, Hochedlinger K, Yamada Y.

Development. 2013 Jan 1;140(1):66-75. doi: 10.1242/dev.084103.

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