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Items: 1 to 20 of 124

1.

The stimulatory adenosine receptor ADORA2B regulates serotonin (5-HT) synthesis and release in oxygen-depleted EC cells in inflammatory bowel disease.

Dammen R, Haugen M, Svejda B, Alaimo D, Brenna O, Pfragner R, Gustafsson BI, Kidd M.

PLoS One. 2013 Apr 26;8(4):e62607. doi: 10.1371/journal.pone.0062607. Erratum in: PLoS One. 2013;8(7). doi:10.1371/annotation/99ad70ea-d3ca-485c-a1b4-50c107941c94. Damen, Rikard [corrected to Dammen, Rikard].

2.

The role of mechanical forces and adenosine in the regulation of intestinal enterochromaffin cell serotonin secretion.

Chin A, Svejda B, Gustafsson BI, Granlund AB, Sandvik AK, Timberlake A, Sumpio B, Pfragner R, Modlin IM, Kidd M.

Am J Physiol Gastrointest Liver Physiol. 2012 Feb 1;302(3):G397-405. doi: 10.1152/ajpgi.00087.2011.

3.

Differential signal pathway activation and 5-HT function: the role of gut enterochromaffin cells as oxygen sensors.

Haugen M, Dammen R, Svejda B, Gustafsson BI, Pfragner R, Modlin I, Kidd M.

Am J Physiol Gastrointest Liver Physiol. 2012 Nov 15;303(10):G1164-73. doi: 10.1152/ajpgi.00027.2012.

4.

Epithelial-specific A2B adenosine receptor signaling protects the colonic epithelial barrier during acute colitis.

Aherne CM, Saeedi B, Collins CB, Masterson JC, McNamee EN, Perrenoud L, Rapp CR, Curtis VF, Bayless A, Fletcher A, Glover LE, Evans CM, Jedlicka P, Furuta GT, de Zoeten EF, Colgan SP, Eltzschig HK.

Mucosal Immunol. 2015 Nov;8(6):1324-38. doi: 10.1038/mi.2015.22. Epub 2015 Apr 8. Erratum in: Mucosal Immunol. 2015 May;8(3):699.

5.

Adenosine A2b receptor promotes progression of human oral cancer.

Kasama H, Sakamoto Y, Kasamatsu A, Okamoto A, Koyama T, Minakawa Y, Ogawara K, Yokoe H, Shiiba M, Tanzawa H, Uzawa K.

BMC Cancer. 2015 Jul 31;15:563. doi: 10.1186/s12885-015-1577-2.

6.

Purinergic autocrine regulation of mechanosensitivity and serotonin release in a human EC model: ATP-gated P2X3 channels in EC are downregulated in ulcerative colitis.

Liñán-Rico A, Wunderlich JE, Grants IS, Frankel WL, Xue J, Williams KC, Harzman AE, Enneking JT, Cooke HJ, Christofi FL.

Inflamm Bowel Dis. 2013 Oct;19(11):2366-79. doi: 10.1097/MIB.0b013e31829ecf4d.

7.

Luminal regulation of normal and neoplastic human EC cell serotonin release is mediated by bile salts, amines, tastants, and olfactants.

Kidd M, Modlin IM, Gustafsson BI, Drozdov I, Hauso O, Pfragner R.

Am J Physiol Gastrointest Liver Physiol. 2008 Aug;295(2):G260-72. doi: 10.1152/ajpgi.00056.2008.

8.

Hypoxia-inducible adenosine A2B receptor modulates proliferation of colon carcinoma cells.

Ma DF, Kondo T, Nakazawa T, Niu DF, Mochizuki K, Kawasaki T, Yamane T, Katoh R.

Hum Pathol. 2010 Nov;41(11):1550-7. doi: 10.1016/j.humpath.2010.04.008.

PMID:
20619442
9.

Elevated ecto-5'-nucleotidase-mediated increased renal adenosine signaling via A2B adenosine receptor contributes to chronic hypertension.

Zhang W, Zhang Y, Wang W, Dai Y, Ning C, Luo R, Sun K, Glover L, Grenz A, Sun H, Tao L, Zhang W, Colgan SP, Blackburn MR, Eltzschig HK, Kellems RE, Xia Y.

Circ Res. 2013 May 24;112(11):1466-78. doi: 10.1161/CIRCRESAHA.111.300166.

10.

Serotonin regulates innate immune responses of colon epithelial cells through Nox2-derived reactive oxygen species.

Regmi SC, Park SY, Ku SK, Kim JA.

Free Radic Biol Med. 2014 Apr;69:377-89. doi: 10.1016/j.freeradbiomed.2014.02.003.

PMID:
24524998
11.

Adenosine modulates HIF-1{alpha}, VEGF, IL-8, and foam cell formation in a human model of hypoxic foam cells.

Gessi S, Fogli E, Sacchetto V, Merighi S, Varani K, Preti D, Leung E, Maclennan S, Borea PA.

Arterioscler Thromb Vasc Biol. 2010 Jan;30(1):90-7. doi: 10.1161/ATVBAHA.109.194902.

12.

Serotonin transporter function and expression are reduced in mice with TNBS-induced colitis.

Linden DR, Foley KF, McQuoid C, Simpson J, Sharkey KA, Mawe GM.

Neurogastroenterol Motil. 2005 Aug;17(4):565-74.

13.

Adenosine A(2)A receptor but not HIF-1 mediates Tyrosine hydroxylase induction in hypoxic PC12 cells.

Gammella E, Cairo G, Tacchini L.

J Neurosci Res. 2010 Jul;88(9):2007-16. doi: 10.1002/jnr.22366.

PMID:
20143408
14.

Analysis of real-time serotonin (5-HT) availability during experimental colitis in mouse.

Bertrand PP, Barajas-Espinosa A, Neshat S, Bertrand RL, Lomax AE.

Am J Physiol Gastrointest Liver Physiol. 2010 Mar;298(3):G446-55. doi: 10.1152/ajpgi.00318.2009.

16.

IL1beta- and LPS-induced serotonin secretion is increased in EC cells derived from Crohn's disease.

Kidd M, Gustafsson BI, Drozdov I, Modlin IM.

Neurogastroenterol Motil. 2009 Apr;21(4):439-50. doi: 10.1111/j.1365-2982.2008.01210.x.

17.

Caffeine inhibits adenosine-induced accumulation of hypoxia-inducible factor-1alpha, vascular endothelial growth factor, and interleukin-8 expression in hypoxic human colon cancer cells.

Merighi S, Benini A, Mirandola P, Gessi S, Varani K, Simioni C, Leung E, Maclennan S, Baraldi PG, Borea PA.

Mol Pharmacol. 2007 Aug;72(2):395-406.

18.

The role of Aurora A in hypoxia-inducible factor 1α-promoting malignant phenotypes of hepatocelluar carcinoma.

Cui SY, Huang JY, Chen YT, Song HZ, Huang GC, De W, Wang R, Chen LB.

Cell Cycle. 2013 Sep 1;12(17):2849-66. doi: 10.4161/cc.25916.

19.

High Glucose Up-regulates ADAM17 through HIF-1α in Mesangial Cells.

Li R, Uttarwar L, Gao B, Charbonneau M, Shi Y, Chan JS, Dubois CM, Krepinsky JC.

J Biol Chem. 2015 Aug 28;290(35):21603-14. doi: 10.1074/jbc.M115.651604.

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