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Items: 1 to 20 of 203

1.

p62/SQSTM1 differentially removes the toxic mutant androgen receptor via autophagy and inclusion formation in a spinal and bulbar muscular atrophy mouse model.

Doi H, Adachi H, Katsuno M, Minamiyama M, Matsumoto S, Kondo N, Miyazaki Y, Iida M, Tohnai G, Qiang Q, Tanaka F, Yanagawa T, Warabi E, Ishii T, Sobue G.

J Neurosci. 2013 May 1;33(18):7710-27. doi: 10.1523/JNEUROSCI.3021-12.2013.

2.

Heat shock protein 70 chaperone overexpression ameliorates phenotypes of the spinal and bulbar muscular atrophy transgenic mouse model by reducing nuclear-localized mutant androgen receptor protein.

Adachi H, Katsuno M, Minamiyama M, Sang C, Pagoulatos G, Angelidis C, Kusakabe M, Yoshiki A, Kobayashi Y, Doyu M, Sobue G.

J Neurosci. 2003 Mar 15;23(6):2203-11.

3.

[Development of therapeutics for spinal and bulbar muscular atrophy (SBMA)].

Sobue G.

Rinsho Shinkeigaku. 2003 Nov;43(11):909-11. Review. Japanese.

PMID:
15152501
4.

Loss of endogenous androgen receptor protein accelerates motor neuron degeneration and accentuates androgen insensitivity in a mouse model of X-linked spinal and bulbar muscular atrophy.

Thomas PS Jr, Fraley GS, Damian V, Woodke LB, Zapata F, Sopher BL, Plymate SR, La Spada AR.

Hum Mol Genet. 2006 Jul 15;15(14):2225-38. Epub 2006 Jun 13. Erratum in: Hum Mol Genet. 2006 Oct 1;15(19):2972. Damien, Vincent [corrected to Damian, Vincent].

PMID:
16772330
5.

CHIP overexpression reduces mutant androgen receptor protein and ameliorates phenotypes of the spinal and bulbar muscular atrophy transgenic mouse model.

Adachi H, Waza M, Tokui K, Katsuno M, Minamiyama M, Tanaka F, Doyu M, Sobue G.

J Neurosci. 2007 May 9;27(19):5115-26.

6.

Pathogenesis and therapy of spinal and bulbar muscular atrophy (SBMA).

Katsuno M, Tanaka F, Adachi H, Banno H, Suzuki K, Watanabe H, Sobue G.

Prog Neurobiol. 2012 Dec;99(3):246-56. doi: 10.1016/j.pneurobio.2012.05.007. Epub 2012 May 15. Review.

PMID:
22609045
7.

Expression of expanded repeat androgen receptor produces neurologic disease in transgenic mice.

Abel A, Walcott J, Woods J, Duda J, Merry DE.

Hum Mol Genet. 2001 Jan 15;10(2):107-16.

PMID:
11152658
8.

Spinal and bulbar muscular atrophy: ligand-dependent pathogenesis and therapeutic perspectives.

Katsuno M, Adachi H, Tanaka F, Sobue G.

J Mol Med (Berl). 2004 May;82(5):298-307. Epub 2004 Feb 27. Review.

PMID:
15133611
9.

Transgenic mouse models of spinal and bulbar muscular atrophy (SBMA).

Katsuno M, Adachi H, Inukai A, Sobue G.

Cytogenet Genome Res. 2003;100(1-4):243-51. Review.

PMID:
14526186
10.

Genistein, a natural product derived from soybeans, ameliorates polyglutamine-mediated motor neuron disease.

Qiang Q, Adachi H, Huang Z, Jiang YM, Katsuno M, Minamiyama M, Doi H, Matsumoto S, Kondo N, Miyazaki Y, Iida M, Tohnai G, Sobue G.

J Neurochem. 2013 Jul;126(1):122-30. doi: 10.1111/jnc.12172. Epub 2013 Feb 27.

11.

Transcriptional activation of TFEB/ZKSCAN3 target genes underlies enhanced autophagy in spinobulbar muscular atrophy.

Chua JP, Reddy SL, Merry DE, Adachi H, Katsuno M, Sobue G, Robins DM, Lieberman AP.

Hum Mol Genet. 2014 Mar 1;23(5):1376-86. doi: 10.1093/hmg/ddt527. Epub 2013 Oct 22.

12.

Cytoplasmic retention of polyglutamine-expanded androgen receptor ameliorates disease via autophagy in a mouse model of spinal and bulbar muscular atrophy.

Montie HL, Cho MS, Holder L, Liu Y, Tsvetkov AS, Finkbeiner S, Merry DE.

Hum Mol Genet. 2009 Jun 1;18(11):1937-50. doi: 10.1093/hmg/ddp115. Epub 2009 Mar 11.

13.

Muscle expression of mutant androgen receptor accounts for systemic and motor neuron disease phenotypes in spinal and bulbar muscular atrophy.

Cortes CJ, Ling SC, Guo LT, Hung G, Tsunemi T, Ly L, Tokunaga S, Lopez E, Sopher BL, Bennett CF, Shelton GD, Cleveland DW, La Spada AR.

Neuron. 2014 Apr 16;82(2):295-307. doi: 10.1016/j.neuron.2014.03.001.

14.

Human adipose-derived mesenchymal stem cells as a new model of spinal and bulbar muscular atrophy.

Dossena M, Bedini G, Rusmini P, Giorgetti E, Canazza A, Tosetti V, Salsano E, Sagnelli A, Mariotti C, Gellera C, Navone SE, Marfia G, Alessandri G, Corsi F, Parati EA, Pareyson D, Poletti A.

PLoS One. 2014 Nov 13;9(11):e112746. doi: 10.1371/journal.pone.0112746. eCollection 2014.

15.

[Molecular-targeted therapy for spinal and bulbar muscular atrophy (SBMA)].

Sobue G.

Rinsho Shinkeigaku. 2010 Nov;50(11):839-41. Review. Japanese.

PMID:
21921465
16.

Enhanced aggregation of androgen receptor in induced pluripotent stem cell-derived neurons from spinal and bulbar muscular atrophy.

Nihei Y, Ito D, Okada Y, Akamatsu W, Yagi T, Yoshizaki T, Okano H, Suzuki N.

J Biol Chem. 2013 Mar 22;288(12):8043-52. doi: 10.1074/jbc.M112.408211. Epub 2013 Jan 30.

17.

[Triplet repeat disease, with particular emphasis of spinal and bulbar muscular atrophy (SBMA)].

Sobue G.

Rinsho Shinkeigaku. 2000 Dec;40(12):1193-5. Japanese.

PMID:
11464455
18.

Clearance of the mutant androgen receptor in motoneuronal models of spinal and bulbar muscular atrophy.

Rusmini P, Crippa V, Giorgetti E, Boncoraglio A, Cristofani R, Carra S, Poletti A.

Neurobiol Aging. 2013 Nov;34(11):2585-603. doi: 10.1016/j.neurobiolaging.2013.05.026. Epub 2013 Jun 28.

19.

Modulation of Hsp90 function in neurodegenerative disorders: a molecular-targeted therapy against disease-causing protein.

Waza M, Adachi H, Katsuno M, Minamiyama M, Tanaka F, Doyu M, Sobue G.

J Mol Med (Berl). 2006 Aug;84(8):635-46. Epub 2006 Jun 2. Review.

PMID:
16741751
20.

Sodium butyrate ameliorates phenotypic expression in a transgenic mouse model of spinal and bulbar muscular atrophy.

Minamiyama M, Katsuno M, Adachi H, Waza M, Sang C, Kobayashi Y, Tanaka F, Doyu M, Inukai A, Sobue G.

Hum Mol Genet. 2004 Jun 1;13(11):1183-92. Epub 2004 Apr 21.

PMID:
15102712

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