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ANKK1 and DRD2 pharmacogenetics of disulfiram treatment for cocaine abuse.

Spellicy CJ, Kosten TR, Hamon SC, Harding MJ, Nielsen DA.

Pharmacogenet Genomics. 2013 Jul;23(7):333-40. doi: 10.1097/FPC.0b013e328361c39d.


Pharmacogenetic randomized trial for cocaine abuse: disulfiram and α1A-adrenoceptor gene variation.

Shorter D, Nielsen DA, Huang W, Harding MJ, Hamon SC, Kosten TR.

Eur Neuropsychopharmacol. 2013 Nov;23(11):1401-7. doi: 10.1016/j.euroneuro.2013.05.014. Epub 2013 Jul 10.


Pharmacogenetic randomized trial for cocaine abuse: disulfiram and dopamine β-hydroxylase.

Kosten TR, Wu G, Huang W, Harding MJ, Hamon SC, Lappalainen J, Nielsen DA.

Biol Psychiatry. 2013 Feb 1;73(3):219-24. doi: 10.1016/j.biopsych.2012.07.011. Epub 2012 Aug 18.


A variant in ANKK1 modulates acute subjective effects of cocaine: a preliminary study.

Spellicy CJ, Harding MJ, Hamon SC, Mahoney JJ 3rd, Reyes JA, Kosten TR, Newton TF, De La Garza R 2nd, Nielsen DA.

Genes Brain Behav. 2014 Jul;13(6):559-64. doi: 10.1111/gbb.12121. Epub 2014 Mar 17.


Randomized clinical trial of disulfiram for cocaine dependence or abuse during buprenorphine treatment.

Schottenfeld RS, Chawarski MC, Cubells JF, George TP, Lappalainen J, Kosten TR.

Drug Alcohol Depend. 2014 Mar 1;136:36-42. doi: 10.1016/j.drugalcdep.2013.12.007. Epub 2013 Dec 25.


The MTHFR C677T Variant is Associated with Responsiveness to Disulfiram Treatment for Cocaine Dependency.

Spellicy CJ, Kosten TR, Hamon SC, Harding MJ, Nielsen DA.

Front Psychiatry. 2013 Jan 14;3:109. doi: 10.3389/fpsyt.2012.00109. eCollection 2012.


Modifying the role of serotonergic 5-HTTLPR and TPH2 variants on disulfiram treatment of cocaine addiction: a preliminary study.

Nielsen DA, Harding MJ, Hamon SC, Huang W, Kosten TR.

Genes Brain Behav. 2012 Nov;11(8):1001-8. doi: 10.1111/j.1601-183X.2012.00839.x. Epub 2012 Sep 27.


Identification of a novel ANKK1 and other dopaminergic (DRD2 and DBH) gene variants in migraine susceptibility.

Ghosh J, Pradhan S, Mittal B.

Neuromolecular Med. 2013 Mar;15(1):61-73. doi: 10.1007/s12017-012-8195-9. Epub 2012 Aug 9.


Genetic variants altering dopamine D2 receptor expression or function modulate the risk of opiate addiction and the dosage requirements of methadone substitution.

Doehring A, Hentig Nv, Graff J, Salamat S, Schmidt M, Geisslinger G, Harder S, Lötsch J.

Pharmacogenet Genomics. 2009 Jun;19(6):407-14. doi: 10.1097/FPC.0b013e328320a3fd.


Family-based association analyses of alcohol dependence phenotypes across DRD2 and neighboring gene ANKK1.

Dick DM, Wang JC, Plunkett J, Aliev F, Hinrichs A, Bertelsen S, Budde JP, Goldstein EL, Kaplan D, Edenberg HJ, Nurnberger J Jr, Hesselbrock V, Schuckit M, Kuperman S, Tischfield J, Porjesz B, Begleiter H, Bierut LJ, Goate A.

Alcohol Clin Exp Res. 2007 Oct;31(10):1645-53.


The ALDH2 and DRD2/ANKK1 genes interacted in bipolar II but not bipolar I disorder.

Lee SY, Chen SL, Chang YH, Chen SH, Chu CH, Huang SY, Tzeng NS, Wang CL, Lee IH, Yeh TL, Yang YK, Lu RB.

Pharmacogenet Genomics. 2010 Aug;20(8):500-6. doi: 10.1097/FPC.0b013e32833caa2b.


Influence of ANKK1 and DRD2 polymorphisms in response to haloperidol.

Giegling I, Balzarro B, Porcelli S, Schäfer M, Hartmann AM, Friedl M, Konte B, Krämer P, Möller HJ, De Ronchi D, Stassen HH, Serretti A, Rujescu D.

Eur Arch Psychiatry Clin Neurosci. 2013 Feb;263(1):65-74. doi: 10.1007/s00406-012-0348-1. Epub 2012 Aug 15.


A DRD2 and ANKK1 haplotype is associated with nicotine dependence.

Voisey J, Swagell CD, Hughes IP, van Daal A, Noble EP, Lawford BR, Young RM, Morris CP.

Psychiatry Res. 2012 Apr 30;196(2-3):285-9. doi: 10.1016/j.psychres.2011.09.024. Epub 2012 Feb 29.


Interaction effect of functional variants of the BDNF and DRD2/ANKK1 gene is associated with alexithymia in healthy human subjects.

Walter NT, Montag C, Markett SA, Reuter M.

Psychosom Med. 2011 Jan;73(1):23-8. doi: 10.1097/PSY.0b013e31820037c1. Epub 2010 Nov 19.


Single nucleotide polymorphisms in ANKK1 and the dopamine D2 receptor gene affect cognitive outcome shortly after traumatic brain injury: a replication and extension study.

McAllister TW, Flashman LA, Harker Rhodes C, Tyler AL, Moore JH, Saykin AJ, McDonald BC, Tosteson TD, Tsongalis GJ.

Brain Inj. 2008 Aug;22(9):705-14. doi: 10.1080/02699050802263019.


Randomized, double blind, placebo-controlled trial of disulfiram for the treatment of cocaine dependence in methadone-stabilized patients.

Oliveto A, Poling J, Mancino MJ, Feldman Z, Cubells JF, Pruzinsky R, Gonsai K, Cargile C, Sofuoglu M, Chopra MP, Gonzalez-Haddad G, Carroll KM, Kosten TR.

Drug Alcohol Depend. 2011 Jan 15;113(2-3):184-91. doi: 10.1016/j.drugalcdep.2010.07.022. Epub 2010 Sep 15.


Association between DRD2/ANKK1 TaqIA Polymorphism and Susceptibility with Tourette Syndrome: A Meta-Analysis.

Yuan A, Su L, Yu S, Li C, Yu T, Sun J.

PLoS One. 2015 Jun 25;10(6):e0131060. doi: 10.1371/journal.pone.0131060. eCollection 2015.


The role of dopamine transporter (SLC6A3) and dopamine D2 receptor/ankyrin repeat and kinase domain containing 1 (DRD2/ANKK1) gene polymorphisms in personality traits.

Kazantseva A, Gaysina D, Malykh S, Khusnutdinova E.

Prog Neuropsychopharmacol Biol Psychiatry. 2011 Jun 1;35(4):1033-40. doi: 10.1016/j.pnpbp.2011.02.013. Epub 2011 Feb 24.


The association of DRD2 -141C and ANKK1 TaqIA polymorphisms with alcohol dependence in Korean population classified by the Lesch typology.

Lee SH, Lee BH, Lee JS, Chai YG, Choi MR, Han DM, Ji H, Jang GH, Shin HE, Choi IG.

Alcohol Alcohol. 2013 Jul-Aug;48(4):426-32. doi: 10.1093/alcalc/agt029. Epub 2013 Apr 4.


Posttraumatic Brain Injury Cognitive Performance Is Moderated by Variation Within ANKK1 and DRD2 Genes.

Failla MD, Myrga JM, Ricker JH, Dixon CE, Conley YP, Wagner AK.

J Head Trauma Rehabil. 2015 Nov-Dec;30(6):E54-66. doi: 10.1097/HTR.0000000000000118.

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