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Items: 1 to 20 of 165

1.

p53 dysfunction precedes the activation of nuclear factor-κB during disease progression in mice expressing Tax, a human T-cell leukemia virus type 1 oncoprotein.

Ohsugi T, Ishida T, Shimasaki T, Okada S, Umezawa K.

Carcinogenesis. 2013 Sep;34(9):2129-36. doi: 10.1093/carcin/bgt144. Epub 2013 Apr 30.

PMID:
23633516
2.

Constitutive activation of NF-kappaB in primary adult T-cell leukemia cells.

Mori N, Fujii M, Ikeda S, Yamada Y, Tomonaga M, Ballard DW, Yamamoto N.

Blood. 1999 Apr 1;93(7):2360-8.

3.

HTLV-I Tax induces a novel interaction between p65/RelA and p53 that results in inhibition of p53 transcriptional activity.

Jeong SJ, Radonovich M, Brady JN, Pise-Masison CA.

Blood. 2004 Sep 1;104(5):1490-7. Epub 2004 May 20. Erratum in: Blood. 2007 Jan 15;109(2):411.

4.

Tax protein-induced expression of antiapoptotic Bfl-1 protein contributes to survival of human T-cell leukemia virus type 1 (HTLV-1)-infected T-cells.

Macaire H, Riquet A, Moncollin V, Biémont-Trescol MC, Duc Dodon M, Hermine O, Debaud AL, Mahieux R, Mesnard JM, Pierre M, Gazzolo L, Bonnefoy N, Valentin H.

J Biol Chem. 2012 Jun 15;287(25):21357-70. doi: 10.1074/jbc.M112.340992. Epub 2012 May 2.

6.

Dual targeting of transformed and untransformed HTLV-1-infected T cells by DHMEQ, a potent and selective inhibitor of NF-kappaB, as a strategy for chemoprevention and therapy of adult T-cell leukemia.

Watanabe M, Ohsugi T, Shoda M, Ishida T, Aizawa S, Maruyama-Nagai M, Utsunomiya A, Koga S, Yamada Y, Kamihira S, Okayama A, Kikuchi H, Uozumi K, Yamaguchi K, Higashihara M, Umezawa K, Watanabe T, Horie R.

Blood. 2005 Oct 1;106(7):2462-71. Epub 2005 Jun 14.

7.

NF-kappaB involvement in the activation of primary adult T-cell leukemia cells and its clinical implications.

Arima N, Matsushita K, Obata H, Ohtsubo H, Fujiwara H, Arimura K, Kukita T, Suruga Y, Wakamatsu S, Hidaka S, Tei C.

Exp Hematol. 1999 Jul;27(7):1168-75.

PMID:
10390192
8.

Inactivation of p53 by human T-cell lymphotropic virus type 1 Tax requires activation of the NF-kappaB pathway and is dependent on p53 phosphorylation.

Pise-Masison CA, Mahieux R, Jiang H, Ashcroft M, Radonovich M, Duvall J, Guillerm C, Brady JN.

Mol Cell Biol. 2000 May;20(10):3377-86.

9.

Human T-cell leukemia virus type 1 Tax induction of NF-kappaB involves activation of the IkappaB kinase alpha (IKKalpha) and IKKbeta cellular kinases.

Geleziunas R, Ferrell S, Lin X, Mu Y, Cunningham ET Jr, Grant M, Connelly MA, Hambor JE, Marcu KB, Greene WC.

Mol Cell Biol. 1998 Sep;18(9):5157-65.

10.

Human T-cell leukemia virus type I tax activates transcription of the human monocyte chemoattractant protein-1 gene through two nuclear factor-kappaB sites.

Mori N, Ueda A, Ikeda S, Yamasaki Y, Yamada Y, Tomonaga M, Morikawa S, Geleziunas R, Yoshimura T, Yamamoto N.

Cancer Res. 2000 Sep 1;60(17):4939-45.

11.
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13.

Inducible nitric oxide synthase mediates DNA double strand breaks in Human T-Cell Leukemia Virus Type 1-induced leukemia/lymphoma.

Baydoun HH, Cherian MA, Green P, Ratner L.

Retrovirology. 2015 Aug 12;12:71. doi: 10.1186/s12977-015-0196-y.

14.

NF-kappaB in pathogenesis and treatment of adult T-cell leukemia/lymphoma.

Horie R.

Int Rev Immunol. 2007 Sep-Dec;26(5-6):269-81. Review.

PMID:
18027201
15.

Arsenic-interferon-alpha-triggered apoptosis in HTLV-I transformed cells is associated with tax down-regulation and reversal of NF-kappa B activation.

El-Sabban ME, Nasr R, Dbaibo G, Hermine O, Abboushi N, Quignon F, Ameisen JC, Bex F, de Thé H, Bazarbachi A.

Blood. 2000 Oct 15;96(8):2849-55.

16.

Human T-cell leukemia virus type 1 Tax oncoprotein represses the expression of the BCL11B tumor suppressor in T-cells.

Takachi T, Takahashi M, Takahashi-Yoshita M, Higuchi M, Obata M, Mishima Y, Okuda S, Tanaka Y, Matsuoka M, Saitoh A, Green PL, Fujii M.

Cancer Sci. 2015 Apr;106(4):461-5. doi: 10.1111/cas.12618. Epub 2015 Mar 16.

17.

Transcriptional activation of hTERT through the NF-kappaB pathway in HTLV-I-transformed cells.

Sinha-Datta U, Horikawa I, Michishita E, Datta A, Sigler-Nicot JC, Brown M, Kazanji M, Barrett JC, Nicot C.

Blood. 2004 Oct 15;104(8):2523-31. Epub 2004 Jun 29.

18.

NF-κB hyper-activation by HTLV-1 tax induces cellular senescence, but can be alleviated by the viral anti-sense protein HBZ.

Zhi H, Yang L, Kuo YL, Ho YK, Shih HM, Giam CZ.

PLoS Pathog. 2011 Apr;7(4):e1002025. doi: 10.1371/journal.ppat.1002025. Epub 2011 Apr 28.

19.

Transcriptional regulation of parathyroid hormone-related protein promoter P2 by NF-kappaB in adult T-cell leukemia/lymphoma.

Nadella MV, Dirksen WP, Nadella KS, Shu S, Cheng AS, Morgenstern JA, Richard V, Fernandez SA, Huang TH, Guttridge D, Rosol TJ.

Leukemia. 2007 Aug;21(8):1752-62. Epub 2007 Jun 7.

20.

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