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Items: 1 to 20 of 92


Regulation of VH replacement by B cell receptor-mediated signaling in human immature B cells.

Liu J, Lange MD, Hong SY, Xie W, Xu K, Huang L, Yu Y, Ehrhardt GR, Zemlin M, Burrows PD, Su K, Carter RH, Zhang Z.

J Immunol. 2013 Jun 1;190(11):5559-66. doi: 10.4049/jimmunol.1102503. Epub 2013 Apr 29.


Internalization of B cell receptors in human EU12 μHC⁺ immature B cells specifically alters downstream signaling events.

Liu J, Xie W, Lange MD, Hong SY, Su K, Zhang Z.

Biomed Res Int. 2013;2013:807240. doi: 10.1155/2013/807240. Epub 2013 Oct 9.


CD19 amplifies B lymphocyte signal transduction by regulating Src-family protein tyrosine kinase activation.

Fujimoto M, Poe JC, Jansen PJ, Sato S, Tedder TF.

J Immunol. 1999 Jun 15;162(12):7088-94.


The molecular basis and biological significance of VH replacement.

Zhang Z, Burrows PD, Cooper MD.

Immunol Rev. 2004 Feb;197:231-42. Review.


Molecular mechanism of serial VH gene replacement.

Zhang Z, Wang YH, Zemlin M, Findley HW, Bridges SL, Burrows PD, Cooper MD.

Ann N Y Acad Sci. 2003 Apr;987:270-3. Review.


Characterization of a new V gene replacement in the absence of activation-induced cytidine deaminase and its contribution to human B-cell receptor diversity.

Ouled-Haddou H, Ghamlouch H, Regnier A, Trudel S, Herent D, Lefranc MP, Marolleau JP, Gubler B.

Immunology. 2014 Feb;141(2):268-75. doi: 10.1111/imm.12192.


Antibody repertoire diversification through VH gene replacement in mice cloned from an IgA plasma cell.

Kumar R, Bach MP, Mainoldi F, Maruya M, Kishigami S, Jumaa H, Wakayama T, Kanagawa O, Fagarasan S, Casola S.

Proc Natl Acad Sci U S A. 2015 Feb 3;112(5):E450-7. doi: 10.1073/pnas.1417988112. Epub 2015 Jan 21.


Contribution of V(H) replacement products in mouse antibody repertoire.

Huang L, Lange MD, Yu Y, Li S, Su K, Zhang Z.

PLoS One. 2013;8(2):e57877. doi: 10.1371/journal.pone.0057877. Epub 2013 Feb 28.


Reconstitution of B cell antigen receptor-induced signaling events in a nonlymphoid cell line by expressing the Syk protein-tyrosine kinase.

Richards JD, Gold MR, Hourihane SL, DeFranco AL, Matsuuchi L.

J Biol Chem. 1996 Mar 15;271(11):6458-66.


Nonredundant roles of Src-family kinases and Syk in the initiation of B-cell antigen receptor signaling.

Stepanek O, Draber P, Drobek A, Horejsi V, Brdicka T.

J Immunol. 2013 Feb 15;190(4):1807-18. doi: 10.4049/jimmunol.1202401. Epub 2013 Jan 18.


VH replacement in mice and humans.

Zhang Z.

Trends Immunol. 2007 Mar;28(3):132-7. Epub 2007 Jan 26. Review.


Monovalent and multivalent ligation of the B cell receptor exhibit differential dependence upon Syk and Src family kinases.

Mukherjee S, Zhu J, Zikherman J, Parameswaran R, Kadlecek TA, Wang Q, Au-Yeung B, Ploegh H, Kuriyan J, Das J, Weiss A.

Sci Signal. 2013 Jan 1;6(256):ra1. doi: 10.1126/scisignal.2003220.


VH replacement rescues progenitor B cells with two nonproductive VDJ alleles.

Lutz J, Müller W, Jäck HM.

J Immunol. 2006 Nov 15;177(10):7007-14.


The activation and subsequent regulatory roles of Lyn and CD19 after B cell receptor ligation are independent.

Xu Y, Beavitt SJ, Harder KW, Hibbs ML, Tarlinton DM.

J Immunol. 2002 Dec 15;169(12):6910-8.

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