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Serum amyloid A promotes lung neutrophilia by increasing IL-17A levels in the mucosa and γδ T cells.

Anthony D, Seow HJ, Uddin M, Thompson M, Dousha L, Vlahos R, Irving LB, Levy BD, Anderson GP, Bozinovski S.

Am J Respir Crit Care Med. 2013 Jul 15;188(2):179-86. doi: 10.1164/rccm.201211-2139OC.


Innate cellular sources of interleukin-17A regulate macrophage accumulation in cigarette- smoke-induced lung inflammation in mice.

Bozinovski S, Seow HJ, Chan SP, Anthony D, McQualter J, Hansen M, Jenkins BJ, Anderson GP, Vlahos R.

Clin Sci (Lond). 2015 Nov;129(9):785-96. doi: 10.1042/CS20140703. Epub 2015 Jul 1.


Serum amyloid A opposes lipoxin A₄ to mediate glucocorticoid refractory lung inflammation in chronic obstructive pulmonary disease.

Bozinovski S, Uddin M, Vlahos R, Thompson M, McQualter JL, Merritt AS, Wark PA, Hutchinson A, Irving LB, Levy BD, Anderson GP.

Proc Natl Acad Sci U S A. 2012 Jan 17;109(3):935-40. doi: 10.1073/pnas.1109382109. Epub 2012 Jan 3.


SAA drives proinflammatory heterotypic macrophage differentiation in the lung via CSF-1R-dependent signaling.

Anthony D, McQualter JL, Bishara M, Lim EX, Yatmaz S, Seow HJ, Hansen M, Thompson M, Hamilton JA, Irving LB, Levy BD, Vlahos R, Anderson GP, Bozinovski S.

FASEB J. 2014 Sep;28(9):3867-77. doi: 10.1096/fj.14-250332. Epub 2014 May 20.


Treating neutrophilic inflammation in COPD by targeting ALX/FPR2 resolution pathways.

Bozinovski S, Anthony D, Anderson GP, Irving LB, Levy BD, Vlahos R.

Pharmacol Ther. 2013 Dec;140(3):280-9. doi: 10.1016/j.pharmthera.2013.07.007. Epub 2013 Jul 21. Review.


Pivotal role of IL-6 in the hyperinflammatory responses to subacute ozone in adiponectin-deficient mice.

Kasahara DI, Kim HY, Mathews JA, Verbout NG, Williams AS, Wurmbrand AP, Ninin FM, Neto FL, Benedito LA, Hug C, Umetsu DT, Shore SA.

Am J Physiol Lung Cell Mol Physiol. 2014 Mar 15;306(6):L508-20. doi: 10.1152/ajplung.00235.2013. Epub 2013 Dec 31.


IL-17A-producing gammadelta T and Th17 lymphocytes mediate lung inflammation but not fibrosis in experimental silicosis.

Lo Re S, Dumoutier L, Couillin I, Van Vyve C, Yakoub Y, Uwambayinema F, Marien B, van den Brûle S, Van Snick J, Uyttenhove C, Ryffel B, Renauld JC, Lison D, Huaux F.

J Immunol. 2010 Jun 1;184(11):6367-77. doi: 10.4049/jimmunol.0900459. Epub 2010 Apr 26.


γδ T cells are required for pulmonary IL-17A expression after ozone exposure in mice: role of TNFα.

Mathews JA, Williams AS, Brand JD, Wurmbrand AP, Chen L, Ninin FM, Si H, Kasahara DI, Shore SA.

PLoS One. 2014 May 13;9(5):e97707. doi: 10.1371/journal.pone.0097707. eCollection 2014.


Natural killer T cell-derived IL-17 mediates lung ischemia-reperfusion injury.

Sharma AK, LaPar DJ, Zhao Y, Li L, Lau CL, Kron IL, Iwakura Y, Okusa MD, Laubach VE.

Am J Respir Crit Care Med. 2011 Jun 1;183(11):1539-49. doi: 10.1164/rccm.201007-1173OC. Epub 2011 Feb 11.


Genetic deletion of IL-17A reduces cigarette smoke-induced inflammation and alveolar type II cell apoptosis.

Chang Y, Al-Alwan L, Audusseau S, Chouiali F, Carlevaro-Fita J, Iwakura Y, Baglole CJ, Eidelman DH, Hamid Q.

Am J Physiol Lung Cell Mol Physiol. 2014 Jan;306(2):L132-43. doi: 10.1152/ajplung.00111.2013. Epub 2013 Oct 4.


Targeting IL-1β and IL-17A driven inflammation during influenza-induced exacerbations of chronic lung inflammation.

Sichelstiel A, Yadava K, Trompette A, Salami O, Iwakura Y, Nicod LP, Marsland BJ.

PLoS One. 2014 Jun 11;9(2):e98440. doi: 10.1371/journal.pone.0098440. eCollection 2014.


IL-17A and the Promotion of Neutrophilia in Acute Exacerbation of Chronic Obstructive Pulmonary Disease.

Roos AB, Sethi S, Nikota J, Wrona CT, Dorrington MG, Sandén C, Bauer CM, Shen P, Bowdish D, Stevenson CS, Erjefält JS, Stampfli MR.

Am J Respir Crit Care Med. 2015 Aug 15;192(4):428-37. doi: 10.1164/rccm.201409-1689OC.


TNF-alpha from inflammatory dendritic cells (DCs) regulates lung IL-17A/IL-5 levels and neutrophilia versus eosinophilia during persistent fungal infection.

Fei M, Bhatia S, Oriss TB, Yarlagadda M, Khare A, Akira S, Saijo S, Iwakura Y, Fallert Junecko BA, Reinhart TA, Foreman O, Ray P, Kolls J, Ray A.

Proc Natl Acad Sci U S A. 2011 Mar 29;108(13):5360-5. doi: 10.1073/pnas.1015476108. Epub 2011 Mar 14.


IL-17A and serum amyloid A are elevated in a cigarette smoke cessation model associated with the persistence of pigmented macrophages, neutrophils and activated NK cells.

Hansen MJ, Chan SP, Langenbach SY, Dousha LF, Jones JE, Yatmaz S, Seow HJ, Vlahos R, Anderson GP, Bozinovski S.

PLoS One. 2014 Nov 18;9(11):e113180. doi: 10.1371/journal.pone.0113180. eCollection 2014.


Interleukin-1 receptor and caspase-1 are required for the Th17 response in nitrogen dioxide-promoted allergic airway disease.

Martin RA, Ather JL, Lundblad LK, Suratt BT, Boyson JE, Budd RC, Alcorn JF, Flavell RA, Eisenbarth SC, Poynter ME.

Am J Respir Cell Mol Biol. 2013 May;48(5):655-64. doi: 10.1165/rcmb.2012-0423OC.


IL-17A Is Elevated in End-Stage Chronic Obstructive Pulmonary Disease and Contributes to Cigarette Smoke-induced Lymphoid Neogenesis.

Roos AB, Sandén C, Mori M, Bjermer L, Stampfli MR, Erjefält JS.

Am J Respir Crit Care Med. 2015 Jun 1;191(11):1232-41. doi: 10.1164/rccm.201410-1861OC.


Microbiota Promotes Chronic Pulmonary Inflammation by Enhancing IL-17A and Autoantibodies.

Yadava K, Pattaroni C, Sichelstiel AK, Trompette A, Gollwitzer ES, Salami O, von Garnier C, Nicod LP, Marsland BJ.

Am J Respir Crit Care Med. 2016 May 1;193(9):975-87. doi: 10.1164/rccm.201504-0779OC.


[The role of interleukin 17A in inducing neutrophilic inflammation in the pulmonary tract].

Semik-Orzech A, Barczyk A, Pierzchała W.

Pol Merkur Lekarski. 2007 Mar;22(129):163-8. Polish.


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