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Items: 1 to 20 of 96

1.

[The effect of PNS on the content and activity of alpha-secretase in the brains of SAMP8 mice with alzheimer's disease].

Huang JL, Wu DP, Lu L, Li F, Zhong ZG.

Zhong Yao Cai. 2012 Nov;35(11):1805-8. Chinese.

PMID:
23627094
2.

[Effect of Panax notoginseng saponins on expression of alpha-secretase mRNA in brains of senescence-accelerated SAMP8 mice].

Huang J, Li F, Wu D, Lu L, Gao Y, Zhong Z.

Zhongguo Zhong Yao Za Zhi. 2012 Jul;37(14):2127-9. Chinese.

PMID:
23126198
3.

[Effect of PNS on the activity and content of BACE1 in the brain of SAMP8 mice with Alzheimer's disease].

Huang JL, Lu L, Huang D, Wu DP, Zhong ZG.

Zhongguo Zhong Xi Yi Jie He Za Zhi. 2013 Jul;33(7):944-7. Chinese.

PMID:
24063218
4.

Effects of Panax notoginseng saponin on α, β, and γ secretase involved in Aβ deposition in SAMP8 mice.

Huang J, Wu D, Wang J, Li F, Lu L, Gao Y, Zhong Z.

Neuroreport. 2014 Jan 22;25(2):89-93. doi: 10.1097/WNR.0000000000000048.

PMID:
24165110
5.

[Effect of Panax notoginseng saponins on APP gene transcription in the brain tissue of SAMP8].

Zhong ZG, Lv L, Chai LM, Wu DP, Zhang WY, Huang JL, Gang YW, Li F, Zu B.

Zhong Yao Cai. 2011 Jan;34(1):77-80. Chinese.

PMID:
21818973
7.

[Effect of Panax notoginseng saponins on syp and tau gene expression in brain of senescence accelerated mouse].

Lv L, Zhong Z, Wu D, Chai L, Zhang W.

Zhongguo Zhong Yao Za Zhi. 2009 May;34(10):1261-3. Chinese.

PMID:
19673391
8.

Putative function of ADAM9, ADAM10, and ADAM17 as APP alpha-secretase.

Asai M, Hattori C, Szabó B, Sasagawa N, Maruyama K, Tanuma S, Ishiura S.

Biochem Biophys Res Commun. 2003 Jan 31;301(1):231-5.

PMID:
12535668
9.

ADAM9 inhibition increases membrane activity of ADAM10 and controls α-secretase processing of amyloid precursor protein.

Moss ML, Powell G, Miller MA, Edwards L, Qi B, Sang QX, De Strooper B, Tesseur I, Lichtenthaler SF, Taverna M, Zhong JL, Dingwall C, Ferdous T, Schlomann U, Zhou P, Griffith LG, Lauffenburger DA, Petrovich R, Bartsch JW.

J Biol Chem. 2011 Nov 25;286(47):40443-51. doi: 10.1074/jbc.M111.280495.

11.

Reducing iron in the brain: a novel pharmacologic mechanism of huperzine A in the treatment of Alzheimer's disease.

Huang XT, Qian ZM, He X, Gong Q, Wu KC, Jiang LR, Lu LN, Zhu ZJ, Zhang HY, Yung WH, Ke Y.

Neurobiol Aging. 2014 May;35(5):1045-54. doi: 10.1016/j.neurobiolaging.2013.11.004.

PMID:
24332448
12.

Melatonin stimulates the nonamyloidogenic processing of βAPP through the positive transcriptional regulation of ADAM10 and ADAM17.

Shukla M, Htoo HH, Wintachai P, Hernandez JF, Dubois C, Postina R, Xu H, Checler F, Smith DR, Govitrapong P, Vincent B.

J Pineal Res. 2015 Mar;58(2):151-65. doi: 10.1111/jpi.12200.

PMID:
25491598
13.

Effect of a dominant-negative form of ADAM10 in a mouse model of Alzheimer's disease.

Schroeder A, Fahrenholz F, Schmitt U.

J Alzheimers Dis. 2009;16(2):309-14. doi: 10.3233/JAD-2009-0952.

PMID:
19221420
14.

Upregulation of APP, ADAM10 and ADAM17 in the denervated mouse dentate gyrus.

Del Turco D, Schlaudraff J, Bonin M, Deller T.

PLoS One. 2014 Jan 3;9(1):e84962. doi: 10.1371/journal.pone.0084962.

15.

Up-regulation of the alpha-secretase ADAM10 by retinoic acid receptors and acitretin.

Tippmann F, Hundt J, Schneider A, Endres K, Fahrenholz F.

FASEB J. 2009 Jun;23(6):1643-54. doi: 10.1096/fj.08-121392.

16.

ADAM10 is the physiologically relevant, constitutive alpha-secretase of the amyloid precursor protein in primary neurons.

Kuhn PH, Wang H, Dislich B, Colombo A, Zeitschel U, Ellwart JW, Kremmer E, Rossner S, Lichtenthaler SF.

EMBO J. 2010 Sep 1;29(17):3020-32. doi: 10.1038/emboj.2010.167.

17.

Extract of Caragana sinica as a potential therapeutic option for increasing alpha-secretase gene expression.

Schuck F, Schmitt U, Reinhardt S, Freese C, Lee IS, Thines E, Efferth T, Endres K.

Phytomedicine. 2015 Oct 15;22(11):1027-36. doi: 10.1016/j.phymed.2015.08.001.

PMID:
26407945
18.

PDK1 decreases TACE-mediated α-secretase activity and promotes disease progression in prion and Alzheimer's diseases.

Pietri M, Dakowski C, Hannaoui S, Alleaume-Butaux A, Hernandez-Rapp J, Ragagnin A, Mouillet-Richard S, Haik S, Bailly Y, Peyrin JM, Launay JM, Kellermann O, Schneider B.

Nat Med. 2013 Sep;19(9):1124-31. doi: 10.1038/nm.3302.

PMID:
23955714
19.

Constitutive α- and β-secretase cleavages of the amyloid precursor protein are partially coupled in neurons, but not in frequently used cell lines.

Colombo A, Wang H, Kuhn PH, Page R, Kremmer E, Dempsey PJ, Crawford HC, Lichtenthaler SF.

Neurobiol Dis. 2013 Jan;49:137-47. doi: 10.1016/j.nbd.2012.08.011.

20.

Determination of the proteolytic cleavage sites of the amyloid precursor-like protein 2 by the proteases ADAM10, BACE1 and γ-secretase.

Hogl S, Kuhn PH, Colombo A, Lichtenthaler SF.

PLoS One. 2011;6(6):e21337. doi: 10.1371/journal.pone.0021337.

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