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Gut. 2013 Jul;62(7):1072-84. doi: 10.1136/gutjnl-2012-304353. Epub 2013 Apr 26.

Crohn's disease complicated by strictures: a systematic review.

Author information

1
Department of Pathobiology, Lerner Research Institute, NC22, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA. riederf@ccf.org

Abstract

The occurrence of strictures as a complication of Crohn's disease is a significant clinical problem. No specific antifibrotic therapies are available. This systematic review comprehensively addresses the pathogenesis, epidemiology, prediction, diagnosis and therapy of this disease complication. We also provide specific recommendations for clinical practice and summarise areas that require future investigation.

KEYWORDS:

Crohn's colitis; Fibrogenesis; Fibrosis; IBD Clinical

PMID:
23626373
PMCID:
PMC4884453
DOI:
10.1136/gutjnl-2012-304353
[Indexed for MEDLINE]
Free PMC Article

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