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Items: 1 to 20 of 88

1.

FLIP: molecular switch between apoptosis and necroptosis.

Gong J, Kumar SA, Graham G, Kumar AP.

Mol Carcinog. 2014 Sep;53(9):675-85. doi: 10.1002/mc.22027. Review.

PMID:
23625539
2.

Targeting c-FLIP in cancer.

Shirley S, Micheau O.

Cancer Lett. 2013 May 28;332(2):141-50. doi: 10.1016/j.canlet.2010.10.009. Review.

PMID:
21071136
4.

FLIP as an anti-cancer therapeutic target.

Yang JK.

Yonsei Med J. 2008 Feb 29;49(1):19-27. doi: 10.3349/ymj.2008.49.1.19. Review.

5.

Targeting c-FLICE-like inhibitory protein (CFLAR) in cancer.

Fulda S.

Expert Opin Ther Targets. 2013 Feb;17(2):195-201. doi: 10.1517/14728222.2013.736499. Review.

PMID:
23252466
6.
7.

Inhibition of RIP and c-FLIP enhances TRAIL-induced apoptosis in pancreatic cancer cells.

Wang P, Zhang J, Bellail A, Jiang W, Hugh J, Kneteman NM, Hao C.

Cell Signal. 2007 Nov;19(11):2237-46.

PMID:
17693058
8.

Cellular FLICE-inhibitory protein (c-FLIP) signalling: a key regulator of receptor-mediated apoptosis in physiologic context and in cancer.

Bagnoli M, Canevari S, Mezzanzanica D.

Int J Biochem Cell Biol. 2010 Feb;42(2):210-3. doi: 10.1016/j.biocel.2009.11.015. Review.

PMID:
19932761
9.

Down-regulation of c-FLIP Enhances death of cancer cells by smac mimetic compound.

Cheung HH, Mahoney DJ, Lacasse EC, Korneluk RG.

Cancer Res. 2009 Oct 1;69(19):7729-38. doi: 10.1158/0008-5472.CAN-09-1794.

10.

ABT-737 induces expression of the death receptor 5 and sensitizes human cancer cells to TRAIL-induced apoptosis.

Song JH, Kandasamy K, Kraft AS.

J Biol Chem. 2008 Sep 5;283(36):25003-13. doi: 10.1074/jbc.M802511200.

12.

c-FLIP knockdown induces ligand-independent DR5-, FADD-, caspase-8-, and caspase-9-dependent apoptosis in breast cancer cells.

Day TW, Huang S, Safa AR.

Biochem Pharmacol. 2008 Dec 15;76(12):1694-704. doi: 10.1016/j.bcp.2008.09.007.

13.

FLIP: a flop for execution signals.

Subramaniam K, Hirpara JL, Tucker-Kellogg L, Tucker-Kellogg G, Pervaiz S.

Cancer Lett. 2013 May 28;332(2):151-5. doi: 10.1016/j.canlet.2012.07.005. Review.

PMID:
22781394
14.
15.

Metformin sensitizes human bladder cancer cells to TRAIL-induced apoptosis through mTOR/S6K1-mediated downregulation of c-FLIP.

Zhang T, Wang X, He D, Jin X, Guo P.

Anticancer Drugs. 2014 Sep;25(8):887-97. doi: 10.1097/CAD.0000000000000116.

PMID:
24714080
16.

Human astrocytes are resistant to Fas ligand and tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis.

Song JH, Bellail A, Tse MC, Yong VW, Hao C.

J Neurosci. 2006 Mar 22;26(12):3299-308. Erratum in: J Neurosci. 2006 May 3;26(18):4983.

17.

Critical role for Fas-associated death domain-like interleukin-1-converting enzyme-like inhibitory protein in anoikis resistance and distant tumor formation.

Mawji IA, Simpson CD, Hurren R, Gronda M, Williams MA, Filmus J, Jonkman J, Da Costa RS, Wilson BC, Thomas MP, Reed JC, Glinsky GV, Schimmer AD.

J Natl Cancer Inst. 2007 May 16;99(10):811-22.

PMID:
17505076
18.

Triggering of death receptor apoptotic signaling by human papillomavirus 16 E2 protein in cervical cancer cell lines is mediated by interaction with c-FLIP.

Wang W, Fang Y, Sima N, Li Y, Li W, Li L, Han L, Liao S, Han Z, Gao Q, Li K, Deng D, Meng L, Zhou J, Wang S, Ma D.

Apoptosis. 2011 Jan;16(1):55-66. doi: 10.1007/s10495-010-0543-3.

PMID:
20882347
19.

Calmodulin binding to cellular FLICE-like inhibitory protein modulates Fas-induced signalling.

Pawar PS, Micoli KJ, Ding H, Cook WJ, Kappes JC, Chen Y, McDonald JM.

Biochem J. 2008 Jun 15;412(3):459-68. doi: 10.1042/BJ20071507.

PMID:
18257744
20.

Human T-cell leukemia virus type 1 Tax-deregulated autophagy pathway and c-FLIP expression contribute to resistance against death receptor-mediated apoptosis.

Wang W, Zhou J, Shi J, Zhang Y, Liu S, Liu Y, Zheng D.

J Virol. 2014 Mar;88(5):2786-98. doi: 10.1128/JVI.03025-13.

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