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Items: 1 to 20 of 131

1.

Metabolism of melatonin and biological activity of intermediates of melatoninergic pathway in human skin cells.

Kim TK, Kleszczynski K, Janjetovic Z, Sweatman T, Lin Z, Li W, Reiter RJ, Fischer TW, Slominski AT.

FASEB J. 2013 Jul;27(7):2742-55. doi: 10.1096/fj.12-224691. Epub 2013 Apr 25.

2.

Melatonin and its metabolites accumulate in the human epidermis in vivo and inhibit proliferation and tyrosinase activity in epidermal melanocytes in vitro.

Kim TK, Lin Z, Tidwell WJ, Li W, Slominski AT.

Mol Cell Endocrinol. 2015 Mar 15;404:1-8. doi: 10.1016/j.mce.2014.07.024. Epub 2014 Aug 27.

3.

N1-Acetyl-5-Methoxykynuramine (AMK) is produced in the human epidermis and shows antiproliferative effects.

Kim TK, Lin Z, Li W, Reiter RJ, Slominski AT.

Endocrinology. 2015 May;156(5):1630-6. doi: 10.1210/en.2014-1980. Epub 2015 Feb 13.

4.

Melatonin and its metabolites ameliorate ultraviolet B-induced damage in human epidermal keratinocytes.

Janjetovic Z, Nahmias ZP, Hanna S, Jarrett SG, Kim TK, Reiter RJ, Slominski AT.

J Pineal Res. 2014 Aug;57(1):90-102. doi: 10.1111/jpi.12146. Epub 2014 Jun 28.

6.

Constitutive and UV-induced metabolism of melatonin in keratinocytes and cell-free systems.

Fischer TW, Sweatman TW, Semak I, Sayre RM, Wortsman J, Slominski A.

FASEB J. 2006 Jul;20(9):1564-6. Epub 2006 Jun 22. Erratum in: FASEB J. 2007 Feb;21(2):630.

PMID:
16793870
7.

Oxidation of melatonin and its catabolites, N1-acetyl-N2 -formyl-5-methoxykynuramine and N1-acetyl-5-methoxykynuramine, by activated leukocytes.

Silva SO, Rodrigues MR, Carvalho SR, Catalani LH, Campa A, Ximenes VF.

J Pineal Res. 2004 Oct;37(3):171-5.

PMID:
15357661
8.

Metabolism of melatonin in the skin: Why is it important?

Slominski AT, Semak I, Fischer TW, Kim TK, Kleszczyński K, Hardeland R, Reiter RJ.

Exp Dermatol. 2017 Jul;26(7):563-568. doi: 10.1111/exd.13208. Epub 2017 Mar 23.

PMID:
27619234
9.

One molecule, many derivatives: a never-ending interaction of melatonin with reactive oxygen and nitrogen species?

Tan DX, Manchester LC, Terron MP, Flores LJ, Reiter RJ.

J Pineal Res. 2007 Jan;42(1):28-42. Review.

PMID:
17198536
10.

N1-acetyl-N2-formyl-5-methoxykynuramine is a product of melatonin oxidation in rats.

Rozov SV, Filatova EV, Orlov AA, Volkova AV, Zhloba AR, Blashko EL, Pozdeyev NV.

J Pineal Res. 2003 Nov;35(4):245-50.

PMID:
14521629
11.

Serotoninergic and melatoninergic systems are fully expressed in human skin.

Slominski A, Pisarchik A, Semak I, Sweatman T, Wortsman J, Szczesniewski A, Slugocki G, McNulty J, Kauser S, Tobin DJ, Jing C, Johansson O.

FASEB J. 2002 Jun;16(8):896-8. Epub 2002 Apr 23.

PMID:
12039872
12.

Melanoma cells influence the differentiation pattern of human epidermal keratinocytes.

Kodet O, Lacina L, Krejčí E, Dvořánková B, Grim M, Štork J, Kodetová D, Vlček Č, Šáchová J, Kolář M, Strnad H, Smetana K.

Mol Cancer. 2015 Jan 5;14:1. doi: 10.1186/1476-4598-14-1.

13.

Metabolism of melatonin by cytochrome P450s in rat liver mitochondria and microsomes.

Semak I, Korik E, Antonova M, Wortsman J, Slominski A.

J Pineal Res. 2008 Nov;45(4):515-23. doi: 10.1111/j.1600-079X.2008.00630.x. Epub 2008 Aug 19.

14.

Radioimmunoassay of N-acetyl-N-formyl-5-methoxykynuramine (AFMK): a melatonin oxidative metabolite.

Harthé C, Claudy D, Déchaud H, Vivien-Roels B, Pévet P, Claustrat B.

Life Sci. 2003 Aug 8;73(12):1587-97.

PMID:
12865098
15.

Analysis of N1-acetyl-N2-formyl-5-methoxykynuramine/N1-acetyl-5-methoxy-kynuramine formation from melatonin in mice.

Niu S, Li F, Tan DX, Zhang L, Idle JR, Gonzalez FJ, Ma X.

J Pineal Res. 2010 Sep;49(2):106-14. doi: 10.1111/j.1600-079X.2010.00771.x. Epub 2010 May 27.

16.

Neutrophils as a specific target for melatonin and kynuramines: effects on cytokine release.

Silva SO, Rodrigues MR, Ximenes VF, Bueno-da-Silva AE, Amarante-Mendes GP, Campa A.

J Neuroimmunol. 2004 Nov;156(1-2):146-52.

PMID:
15465605
17.

Melatonin metabolite, N(1)-acetyl-N(1)-formyl-5-methoxykynuramine (AFMK), attenuates acute pancreatitis in the rat: in vivo and in vitro studies.

Jaworek J, Szklarczyk J, Bonior J, Kot M, Goralska M, Pierzchalski P, Reiter RJ, Czech U, Tomaszewska R.

J Physiol Pharmacol. 2016 Jun;67(3):411-21.

18.

Measurement of melatonin and its metabolites: importance for the evaluation of their biological roles.

Martinez GR, Almeida EA, Klitzke CF, Onuki J, Prado FM, Medeiros MH, Di Mascio P.

Endocrine. 2005 Jul;27(2):111-8. Review.

PMID:
16217124
19.

Metabolism of serotonin to N-acetylserotonin, melatonin, and 5-methoxytryptamine in hamster skin culture.

Slominski A, Baker J, Rosano TG, Guisti LW, Ermak G, Grande M, Gaudet SJ.

J Biol Chem. 1996 May 24;271(21):12281-6.

20.

Functional activity of serotoninergic and melatoninergic systems expressed in the skin.

Slominski A, Pisarchik A, Zbytek B, Tobin DJ, Kauser S, Wortsman J.

J Cell Physiol. 2003 Jul;196(1):144-53.

PMID:
12767050

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