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Items: 1 to 20 of 347

1.

Modulation of the endoplasmic reticulum-mitochondria interface in Alzheimer's disease and related models.

Hedskog L, Pinho CM, Filadi R, Rönnbäck A, Hertwig L, Wiehager B, Larssen P, Gellhaar S, Sandebring A, Westerlund M, Graff C, Winblad B, Galter D, Behbahani H, Pizzo P, Glaser E, Ankarcrona M.

Proc Natl Acad Sci U S A. 2013 May 7;110(19):7916-21. doi: 10.1073/pnas.1300677110. Epub 2013 Apr 25.

2.

Mitochondria-associated ER membranes in Alzheimer disease.

Schon EA, Area-Gomez E.

Mol Cell Neurosci. 2013 Jul;55:26-36. doi: 10.1016/j.mcn.2012.07.011. Epub 2012 Aug 24. Review.

3.

Upregulated function of mitochondria-associated ER membranes in Alzheimer disease.

Area-Gomez E, Del Carmen Lara Castillo M, Tambini MD, Guardia-Laguarta C, de Groof AJ, Madra M, Ikenouchi J, Umeda M, Bird TD, Sturley SL, Schon EA.

EMBO J. 2012 Nov 5;31(21):4106-23. doi: 10.1038/emboj.2012.202. Epub 2012 Aug 14.

4.

Presenilin 1 regulates the processing of beta-amyloid precursor protein C-terminal fragments and the generation of amyloid beta-protein in endoplasmic reticulum and Golgi.

Xia W, Zhang J, Ostaszewski BL, Kimberly WT, Seubert P, Koo EH, Shen J, Selkoe DJ.

Biochemistry. 1998 Nov 24;37(47):16465-71.

PMID:
9843412
6.

Tespa1 is a novel component of mitochondria-associated endoplasmic reticulum membranes and affects mitochondrial calcium flux.

Matsuzaki H, Fujimoto T, Tanaka M, Shirasawa S.

Biochem Biophys Res Commun. 2013 Apr 12;433(3):322-6. doi: 10.1016/j.bbrc.2013.02.099. Epub 2013 Mar 15.

PMID:
23501103
7.

Mitofusin-2 knockdown increases ER-mitochondria contact and decreases amyloid β-peptide production.

Leal NS, Schreiner B, Pinho CM, Filadi R, Wiehager B, Karlström H, Pizzo P, Ankarcrona M.

J Cell Mol Med. 2016 Sep;20(9):1686-95. doi: 10.1111/jcmm.12863. Epub 2016 May 20.

8.

Expression of a truncated form of the endoplasmic reticulum chaperone protein, σ1 receptor, promotes mitochondrial energy depletion and apoptosis.

Shioda N, Ishikawa K, Tagashira H, Ishizuka T, Yawo H, Fukunaga K.

J Biol Chem. 2012 Jul 6;287(28):23318-31. doi: 10.1074/jbc.M112.349142. Epub 2012 May 22.

9.

Nicastrin, presenilin, APH-1, and PEN-2 form active gamma-secretase complexes in mitochondria.

Hansson CA, Frykman S, Farmery MR, Tjernberg LO, Nilsberth C, Pursglove SE, Ito A, Winblad B, Cowburn RF, Thyberg J, Ankarcrona M.

J Biol Chem. 2004 Dec 3;279(49):51654-60. Epub 2004 Sep 28.

10.

Interactions of endoplasmic reticulum and mitochondria Ca(2+) stores with capacitative calcium entry.

Huang HM, Chen HL, Gibson GE.

Metab Brain Dis. 2014 Dec;29(4):1083-93. doi: 10.1007/s11011-014-9541-4. Epub 2014 Apr 22.

11.

On the Pathogenesis of Alzheimer's Disease: The MAM Hypothesis.

Area-Gomez E, Schon EA.

FASEB J. 2017 Mar;31(3):864-867. doi: 10.1096/fj.201601309. Review.

PMID:
28246299
12.

Mitochondrial amyloid-beta levels are associated with the extent of mitochondrial dysfunction in different brain regions and the degree of cognitive impairment in Alzheimer's transgenic mice.

Dragicevic N, Mamcarz M, Zhu Y, Buzzeo R, Tan J, Arendash GW, Bradshaw PC.

J Alzheimers Dis. 2010;20 Suppl 2:S535-50. doi: 10.3233/JAD-2010-100342.

PMID:
20463404
13.

Perturbed endoplasmic reticulum function, synaptic apoptosis and the pathogenesis of Alzheimer's disease.

Mattson MP, Gary DS, Chan SL, Duan W.

Biochem Soc Symp. 2001;(67):151-62. Review.

PMID:
11447832
14.

Melatonin treatment restores mitochondrial function in Alzheimer's mice: a mitochondrial protective role of melatonin membrane receptor signaling.

Dragicevic N, Copes N, O'Neal-Moffitt G, Jin J, Buzzeo R, Mamcarz M, Tan J, Cao C, Olcese JM, Arendash GW, Bradshaw PC.

J Pineal Res. 2011 Aug;51(1):75-86. doi: 10.1111/j.1600-079X.2011.00864.x. Epub 2011 Mar 1.

PMID:
21355879
15.

Feature Article: mTOR complex 2-Akt signaling at mitochondria-associated endoplasmic reticulum membranes (MAM) regulates mitochondrial physiology.

Betz C, Stracka D, Prescianotto-Baschong C, Frieden M, Demaurex N, Hall MN.

Proc Natl Acad Sci U S A. 2013 Jul 30;110(31):12526-34. doi: 10.1073/pnas.1302455110. Epub 2013 Jul 12.

16.

Amyloid-β peptides are generated in mitochondria-associated endoplasmic reticulum membranes.

Schreiner B, Hedskog L, Wiehager B, Ankarcrona M.

J Alzheimers Dis. 2015;43(2):369-74. doi: 10.3233/JAD-132543.

PMID:
25096627
17.

An endoplasmic-reticulum-specific apoptotic pathway is involved in prion and amyloid-beta peptides neurotoxicity.

Ferreiro E, Resende R, Costa R, Oliveira CR, Pereira CM.

Neurobiol Dis. 2006 Sep;23(3):669-78. Epub 2006 Jul 17.

PMID:
16844381
18.

Detergent-resistant microdomains determine the localization of sigma-1 receptors to the endoplasmic reticulum-mitochondria junction.

Hayashi T, Fujimoto M.

Mol Pharmacol. 2010 Apr;77(4):517-28. doi: 10.1124/mol.109.062539. Epub 2010 Jan 6.

19.

Ca2+ dysregulation in neurons from transgenic mice expressing mutant presenilin 2.

Kipanyula MJ, Contreras L, Zampese E, Lazzari C, Wong AK, Pizzo P, Fasolato C, Pozzan T.

Aging Cell. 2012 Oct;11(5):885-93. doi: 10.1111/j.1474-9726.2012.00858.x. Epub 2012 Aug 7.

20.

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