Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 77


Lipid IVa incompletely activates MyD88-independent Toll-like receptor 4 signaling in mouse macrophage cell lines.

Ogura N, Muroi M, Sugiura Y, Tanamoto K.

Pathog Dis. 2013 Apr;67(3):199-205. doi: 10.1111/2049-632X.12031. Epub 2013 Mar 4.


Differential induction of the toll-like receptor 4-MyD88-dependent and -independent signaling pathways by endotoxins.

Zughaier SM, Zimmer SM, Datta A, Carlson RW, Stephens DS.

Infect Immun. 2005 May;73(5):2940-50. Erratum in: Infect Immun. 2006 May;74(5):3077.


MyD88-dependent SHIP1 regulates proinflammatory signaling pathways in dendritic cells after monophosphoryl lipid A stimulation of TLR4.

Cekic C, Casella CR, Sag D, Antignano F, Kolb J, Suttles J, Hughes MR, Krystal G, Mitchell TC.

J Immunol. 2011 Apr 1;186(7):3858-65. doi: 10.4049/jimmunol.1001034. Epub 2011 Feb 21.


Melatonin modulates TLR4-mediated inflammatory genes through MyD88- and TRIF-dependent signaling pathways in lipopolysaccharide-stimulated RAW264.7 cells.

Xia MZ, Liang YL, Wang H, Chen X, Huang YY, Zhang ZH, Chen YH, Zhang C, Zhao M, Xu DX, Song LH.

J Pineal Res. 2012 Nov;53(4):325-34. doi: 10.1111/j.1600-079X.2012.01002.x. Epub 2012 Apr 27.


Structural regions of MD-2 that determine the agonist-antagonist activity of lipid IVa.

Muroi M, Tanamoto K.

J Biol Chem. 2006 Mar 3;281(9):5484-91. Epub 2005 Dec 31.


Uropathogenic Escherichia coli block MyD88-dependent and activate MyD88-independent signaling pathways in rat testicular cells.

Bhushan S, Tchatalbachev S, Klug J, Fijak M, Pineau C, Chakraborty T, Meinhardt A.

J Immunol. 2008 Apr 15;180(8):5537-47.


Lipid A antagonist, lipid IVa, is distinct from lipid A in interaction with Toll-like receptor 4 (TLR4)-MD-2 and ligand-induced TLR4 oligomerization.

Saitoh S, Akashi S, Yamada T, Tanimura N, Kobayashi M, Konno K, Matsumoto F, Fukase K, Kusumoto S, Nagai Y, Kusumoto Y, Kosugi A, Miyake K.

Int Immunol. 2004 Jul;16(7):961-9. Epub 2004 Jun 7.


The critical role of toll-like receptor (TLR) 4 in alcoholic liver disease is independent of the common TLR adapter MyD88.

Hritz I, Mandrekar P, Velayudham A, Catalano D, Dolganiuc A, Kodys K, Kurt-Jones E, Szabo G.

Hepatology. 2008 Oct;48(4):1224-31. doi: 10.1002/hep.22470.


The scaffold MyD88 acts to couple protein kinase Cepsilon to Toll-like receptors.

Faisal A, Saurin A, Gregory B, Foxwell B, Parker PJ.

J Biol Chem. 2008 Jul 4;283(27):18591-600. doi: 10.1074/jbc.M710330200. Epub 2008 May 5.


PKC-alpha controls MYD88-dependent TLR/IL-1R signaling and cytokine production in mouse and human dendritic cells.

Langlet C, Springael C, Johnson J, Thomas S, Flamand V, Leitges M, Goldman M, Aksoy E, Willems F.

Eur J Immunol. 2010 Feb;40(2):505-15. doi: 10.1002/eji.200939391.


Role for MyD88-independent, TRIF pathway in lipid A/TLR4-induced endotoxin tolerance.

Biswas SK, Bist P, Dhillon MK, Kajiji T, Del Fresno C, Yamamoto M, Lopez-Collazo E, Akira S, Tergaonkar V.

J Immunol. 2007 Sep 15;179(6):4083-92.


MyD88-dependent Toll-like receptor signaling is required for murine macrophages response to IS2.

Li H, Kim WJ, Jiang J, Lee SH, Youn HS, Moon EY, Kim TJ, Ye SK, Ryu JH, Kang TB, Koppula S, Park PJ, Choi DK, Lee KH.

Int Immunopharmacol. 2011 Oct;11(10):1578-83. doi: 10.1016/j.intimp.2011.05.017. Epub 2011 May 31.


Inhibition of TIR domain signaling by TcpC: MyD88-dependent and independent effects on Escherichia coli virulence.

Yadav M, Zhang J, Fischer H, Huang W, Lutay N, Cirl C, Lum J, Miethke T, Svanborg C.

PLoS Pathog. 2010 Sep 23;6(9):e1001120. doi: 10.1371/journal.ppat.1001120.


The induction of macrophage gene expression by LPS predominantly utilizes Myd88-independent signaling cascades.

Björkbacka H, Fitzgerald KA, Huet F, Li X, Gregory JA, Lee MA, Ordija CM, Dowley NE, Golenbock DT, Freeman MW.

Physiol Genomics. 2004 Nov 17;19(3):319-30. Epub 2004 Sep 14.


Toll-like receptor interactions: tolerance of MyD88-dependent cytokines but enhancement of MyD88-independent interferon-beta production.

Broad A, Kirby JA, Jones DE; Applied Immunology and Transplantation Research Group.

Immunology. 2007 Jan;120(1):103-11. Epub 2006 Oct 11. Erratum in: Immunology. 2007 Mar;120(3):433.

Supplemental Content

Support Center