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Items: 1 to 20 of 57

1.

Concurrent regulation of the transcription factors Nrf2 and ATF4 mediates the enhancement of glutathione levels by the flavonoid fisetin.

Ehren JL, Maher P.

Biochem Pharmacol. 2013 Jun 15;85(12):1816-26. doi: 10.1016/j.bcp.2013.04.010. Epub 2013 Apr 22.

PMID:
23618921
2.

Gamma-tocopheryl quinone, not alpha-tocopheryl quinone, induces adaptive response through up-regulation of cellular glutathione and cysteine availability via activation of ATF4.

Ogawa Y, Saito Y, Nishio K, Yoshida Y, Ashida H, Niki E.

Free Radic Res. 2008 Jul;42(7):674-87. doi: 10.1080/10715760802277396.

PMID:
18654882
3.

Oxidized phospholipids regulate expression of ATF4 and VEGF in endothelial cells via NRF2-dependent mechanism: novel point of convergence between electrophilic and unfolded protein stress pathways.

Afonyushkin T, Oskolkova OV, Philippova M, Resink TJ, Erne P, Binder BR, Bochkov VN.

Arterioscler Thromb Vasc Biol. 2010 May;30(5):1007-13. doi: 10.1161/ATVBAHA.110.204354. Epub 2010 Feb 25.

4.

Transcriptional regulation of activating transcription factor 4 under oxidative stress in retinal pigment epithelial ARPE-19/HPV-16 cells.

Miyamoto N, Izumi H, Miyamoto R, Bin H, Kondo H, Tawara A, Sasaguri Y, Kohno K.

Invest Ophthalmol Vis Sci. 2011 Mar 2;52(3):1226-34. doi: 10.1167/iovs.10-5775.

PMID:
21087962
6.

Nrf2-regulated glutathione recycling independent of biosynthesis is critical for cell survival during oxidative stress.

Harvey CJ, Thimmulappa RK, Singh A, Blake DJ, Ling G, Wakabayashi N, Fujii J, Myers A, Biswal S.

Free Radic Biol Med. 2009 Feb 15;46(4):443-53. doi: 10.1016/j.freeradbiomed.2008.10.040. Epub 2008 Nov 5.

7.

Activation of Nrf2-mediated oxidative stress response in macrophages by hypochlorous acid.

Pi J, Zhang Q, Woods CG, Wong V, Collins S, Andersen ME.

Toxicol Appl Pharmacol. 2008 Feb 1;226(3):236-43. Epub 2007 Sep 26.

PMID:
17980396
8.
9.

Endogenous hydrogen peroxide regulates glutathione redox via nuclear factor erythroid 2-related factor 2 downstream of phosphatidylinositol 3-kinase during muscle differentiation.

Ding Y, Choi KJ, Kim JH, Han X, Piao Y, Jeong JH, Choe W, Kang I, Ha J, Forman HJ, Lee J, Yoon KS, Kim SS.

Am J Pathol. 2008 Jun;172(6):1529-41. doi: 10.2353/ajpath.2008.070429. Epub 2008 May 5.

10.

Transcription factor Nrf2 protects HepG2 cells against CYP2E1 plus arachidonic acid-dependent toxicity.

Gong P, Cederbaum AI.

J Biol Chem. 2006 May 26;281(21):14573-9. Epub 2006 Mar 21.

11.
12.

Significance of the rapid increase in GSH levels in the protective response to cadmium exposure through phosphorylated Nrf2 signaling in Jurkat T-cells.

Ogasawara Y, Takeda Y, Takayama H, Nishimoto S, Ichikawa K, Ueki M, Suzuki T, Ishii K.

Free Radic Biol Med. 2014 Apr;69:58-66. doi: 10.1016/j.freeradbiomed.2014.01.005. Epub 2014 Jan 15.

PMID:
24440467
13.

Control of redox state and redox signaling by neural antioxidant systems.

Lewerenz J, Maher P.

Antioxid Redox Signal. 2011 Apr 15;14(8):1449-65. doi: 10.1089/ars.2010.3600. Epub 2011 Feb 3. Review.

PMID:
20812872
14.

Integrated stress response modulates cellular redox state via induction of cystathionine γ-lyase: cross-talk between integrated stress response and thiol metabolism.

Dickhout JG, Carlisle RE, Jerome DE, Mohammed-Ali Z, Jiang H, Yang G, Mani S, Garg SK, Banerjee R, Kaufman RJ, Maclean KN, Wang R, Austin RC.

J Biol Chem. 2012 Mar 2;287(10):7603-14. doi: 10.1074/jbc.M111.304576. Epub 2012 Jan 3.

15.

Coordinate regulation of glutathione metabolism in astrocytes by Nrf2.

Sun X, Erb H, Murphy TH.

Biochem Biophys Res Commun. 2005 Jan 14;326(2):371-7.

PMID:
15582588
16.

Nrf2 and antioxidant defense against CYP2E1 toxicity.

Cederbaum A.

Expert Opin Drug Metab Toxicol. 2009 Oct;5(10):1223-44. doi: 10.1517/17425250903143769. Review.

PMID:
19671018
17.

Review of molecular mechanisms involved in the activation of the Nrf2-ARE signaling pathway by chemopreventive agents.

Giudice A, Arra C, Turco MC.

Methods Mol Biol. 2010;647:37-74. doi: 10.1007/978-1-60761-738-9_3. Review.

PMID:
20694660
18.

Flavonoids protect cerebrovascular endothelial cells through Nrf2 and PI3K from β-amyloid peptide-induced oxidative damage.

Xi YD, Yu HL, Ding J, Ma WW, Yuan LH, Feng JF, Xiao YX, Xiao R.

Curr Neurovasc Res. 2012 Feb;9(1):32-41.

PMID:
22272764
19.

Mutation of ATF4 mediates resistance of neuronal cell lines against oxidative stress by inducing xCT expression.

Lewerenz J, Sato H, Albrecht P, Henke N, Noack R, Methner A, Maher P.

Cell Death Differ. 2012 May;19(5):847-58. doi: 10.1038/cdd.2011.165. Epub 2011 Nov 18.

20.

Deletion of nuclear factor-E2-related factor-2 leads to rapid onset and progression of nutritional steatohepatitis in mice.

Sugimoto H, Okada K, Shoda J, Warabi E, Ishige K, Ueda T, Taguchi K, Yanagawa T, Nakahara A, Hyodo I, Ishii T, Yamamoto M.

Am J Physiol Gastrointest Liver Physiol. 2010 Feb;298(2):G283-94. doi: 10.1152/ajpgi.00296.2009. Epub 2009 Nov 19.

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