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23617482,19936752,24635675,20160602,24113431,19000867,25794062,8310908,21382681,16389980,24598443,16608057,19896069,23341178,15935966,12468069,20807851,18496038,23480965,27842670,24119347,19034026,11930067,22977323,14736690,17721333,3289096,21512042,19394873,18356433,22482621,29206596,25478740,25592026,29336601,24625084,20599062,18562756,16979068,21776798,10580945,8320065,24074648,17885070,15132504,23239691,31714194,17386991,22960243,27439324,21493789,18664845,20152726,12034953,27549084,17899105,34706849,12468068,26337439,16843852,20437132,19561261,7618538,21621935,19524456,14752180,18280930,16898468,15537839,32198572,21982461,31822774,17945689,26443601,28454640,19204454,20346728,19748002,16685910,7824718,21232683,26780639,14626305,23255744,22447377,19104438,20042351,22763504,9304567,24475812,18423313,22021501,34983100,19843717,21946054,21512043,17763856,32350657,25226989,21227621,22573302,19760237,34663260,24594424,18425520,18383684,12462722,27249174,17929026,31521323,24789046,30251934,7858017,25892052,19030967,30048344,17581707,31084482,20966775,19268859,30269955,33439320,21718956,24304703,29948089,32940850,28095493,32592003,32681587,28338536,36944548,21978447,24045247,18239963,23206609,26994093,28732268,20354756,33754828,17964464,33310553,34404517,24331262,19064209,32052750,12819915,17874330,23592767,25249448,34871936,20171819,34964851,22710985,34349135,19418048,16958413,27897029,10659737,23827799,20574707,28914743,29063257,36749213,25247691,36121622,16752573,15235812,22920355,21963532,21618054,7734535,10696599,30097402,21307781,22993220,20879340,25533196,23344916,31385049,31748854,25168020,22327922,21430930,26071244,28914745,36719681,33879750,24481755,16872098,22422390,23601768,20680290,29860192,30536611,15035515,28687285,31352639,23239692,25279774,34463551,23177084,11724042,21225269,24463780,36747927,23965786,26783697,32305166,22744323,36266099,26769904,32615493,25844978,16274004,16632719,16875305,24480168,16585729,26774737,23880041,24481756,15035518,1607261,11695768,27879399,23059738,28301584,28299236,17354808,35059804,25757629,18278373,9419461,24834889,22919013,18383680,9419471,10342250,15789582,28800950,34023068,20879456,15895587,20473605,30803897,26153580,32797309,19421813,12494950,23515916,15000360,16049406,31583870,19000872,20077046,23756324,23193306,30415174,23096210,7734544,12009184,2233573,24647055,22824118,22573300,2654595,30848498,10036665,17985636,16086181,18085401,18415648,9059410,8883514,22999524,3154652,22255505,3841098,9561264,30292273,34603989,30062525,24119266,21113748,34164165,28594923,22476393,32692300,9484539,20837383,16878569,9061081,34491128,8375997,26688067,28678671,22573296,22958720,30523140,34264351,2807801,22422436,11016758,12520223,27016368,10984239,22386166,23473723,25018075,3519523,28301779,20386949,12201421,25833276,2299703,12077573,21917487,18196808,26582331,17985637,10847358,25764733,17047961,21498301,30706143,16819607,16467210,31793848,24710435,29671208,21170689,30457988,10988180,17492289,22139721,24043613,23664399,20693106,27589577,15578184,2394573,26775736,10565509,2394571,19616909,34531429,21859026,32186414,36725356,30134902,8761397,32796198,28290335,1441929,8439582,26774736,8496031,8892259,2668346,16132028,31900698,8700023,16964489,33733827,19937084,26363824,22526116,26930386,30901052,19965010,24132005,20095280,19910216,7033756,22627615,27578931,9399168,18292998,15273610,32218458,24962823,18310996,9750890,6378985,10587911,30460476,8139837,11797942,23527241,36419044,28293771,26981449,1574677,15841739,34115023,25706581,1601603,22369530,9165420,3980173,19020936,28549868,29990381,31946070,29489595,33284983,30399157,12973297,26842827,35819922,34173973,27126741,32032249,32195958,3980184,8521113,8946368,8276583,33060837,20821140,15255518,25247972,10846136,30187317,28488239,12945920,15559126,36788769,22606675,3546401,9484540,8478167,36731328,15472663,8208221,10069054,11522420,24462387,31407523,12238545,1291302,34903808,8462582,1830564,31439238,26916249,24697724,30802232,35032722,10505863,24414539,25370651,36426577,10505862,31273458,12753368,2394572,15147016,10435534,7643802,23103185,33181168,9156229,7970605,3514175,11675166,9261456,16715659,33090731,10772355,26616209,9894954,7203903,35866566,19070238,32275586,36980397,31341514,25996917,25842163,9676455,10674457,28660305,2644313,27372536,26687748,30802231,30255391,10634663,3908387,22088998,2488037,1885270,28161024,25163057,27571965,8413042,2191935,26158028,34679547,9442202,18431577,31199712,26123980,3840457,26795300,36580596,25966290,31579657,11131054,27266374,3480566,14983118,19926496,28154988,31773501,11216912,7076447,22271817,10696596,22802764,2032824,2394569,22729550,21306373,32807855,33283889,16049413,24313347,31388865,27277055,22033725,9035277,21966613,36118268,28336945,31110895,32288148,24049870,35405724,20734197,25005866,31147237,34403144,27239987,8332421,2011919,17281694,3733381,32096940,19953192,31297630,35785555,26811839[uid]

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Comparison of dual-energy subtraction and electronic bone suppression combined with computer-aided detection on chest radiographs: effect on human observers' performance in nodule detection.

Szucs-Farkas Z, Schick A, Cullmann JL, Ebner L, Megyeri B, Vock P, Christe A. Szucs-Farkas Z, et al. AJR Am J Roentgenol. 2013 May;200(5):1006-13. doi: 10.2214/AJR.12.8877. AJR Am J Roentgenol. 2013. PMID: 23617482 Free article. Clinical Trial.

Improved detection of pulmonary nodules on energy-subtracted chest radiographs with a commercial computer-aided diagnosis software: comparison with human observers.

Szucs-Farkas Z, Patak MA, Yuksel-Hatz S, Ruder T, Vock P. Szucs-Farkas Z, et al. Eur Radiol. 2010 Jun;20(6):1289-96. doi: 10.1007/s00330-009-1667-0. Epub 2009 Nov 21. Eur Radiol. 2010. PMID: 19936752 Free article.

Computer-aided detection improves detection of pulmonary nodules in chest radiographs beyond the support by bone-suppressed images.

Schalekamp S, van Ginneken B, Koedam E, Snoeren MM, Tiehuis AM, Wittenberg R, Karssemeijer N, Schaefer-Prokop CM. Schalekamp S, et al. Radiology. 2014 Jul;272(1):252-61. doi: 10.1148/radiol.14131315. Epub 2014 Mar 12. Radiology. 2014. PMID: 24635675

Dual energy subtraction digital radiography improves performance of a next generation computer-aided detection program.

Balkman JD, Mehandru S, DuPont E, Novak RD, Gilkeson RC. Balkman JD, et al. J Thorac Imaging. 2010 Feb;25(1):41-7. doi: 10.1097/RTI.0b013e3181aa34ed. J Thorac Imaging. 2010. PMID: 20160602

Bone suppressed images improve radiologists' detection performance for pulmonary nodules in chest radiographs.

Schalekamp S, van Ginneken B, Meiss L, Peters-Bax L, Quekel LG, Snoeren MM, Tiehuis AM, Wittenberg R, Karssemeijer N, Schaefer-Prokop CM. Schalekamp S, et al. Eur J Radiol. 2013 Dec;82(12):2399-405. doi: 10.1016/j.ejrad.2013.09.016. Epub 2013 Sep 25. Eur J Radiol. 2013. PMID: 24113431

Evaluation of computer-aided diagnosis (CAD) software for the detection of lung nodules on multidetector row computed tomography (MDCT): JAFROC study for the improvement in radiologists' diagnostic accuracy.

Hirose T, Nitta N, Shiraishi J, Nagatani Y, Takahashi M, Murata K. Hirose T, et al. Acad Radiol. 2008 Dec;15(12):1505-12. doi: 10.1016/j.acra.2008.06.009. Acad Radiol. 2008. PMID: 19000867

Lung nodule detection by microdose CT versus chest radiography (standard and dual-energy subtracted).

Ebner L, Bütikofer Y, Ott D, Huber A, Landau J, Roos JE, Heverhagen JT, Christe A. Ebner L, et al. AJR Am J Roentgenol. 2015 Apr;204(4):727-35. doi: 10.2214/AJR.14.12921. AJR Am J Roentgenol. 2015. PMID: 25794062

Conventional chest radiography vs dual-energy computed radiography in the detection and characterization of pulmonary nodules.

Kelcz F, Zink FE, Peppler WW, Kruger DG, Ergun DL, Mistretta CA. Kelcz F, et al. AJR Am J Roentgenol. 1994 Feb;162(2):271-8. doi: 10.2214/ajr.162.2.8310908. AJR Am J Roentgenol. 1994. PMID: 8310908

Usefulness of computerized method for lung nodule detection on digital chest radiographs using similar subtraction images from different patients.

Aoki T, Oda N, Yamashita Y, Yamamoto K, Korogi Y. Aoki T, et al. Eur J Radiol. 2012 May;81(5):1062-7. doi: 10.1016/j.ejrad.2011.02.010. Epub 2011 Mar 5. Eur J Radiol. 2012. PMID: 21382681

Clinical evaluation of pulmonary nodules with dual-exposure dual-energy subtraction chest radiography.

Uemura M, Miyagawa M, Yasuhara Y, Murakami T, Ikura H, Sakamoto K, Tagashira H, Arakawa K, Mochizuki T. Uemura M, et al. Radiat Med. 2005 Sep;23(6):391-7. Radiat Med. 2005. PMID: 16389980 Clinical Trial.

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