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Items: 1 to 20 of 94

1.

A conserved gammaherpesvirus protein kinase targets histone deacetylases 1 and 2 to facilitate viral replication in primary macrophages.

Mounce BC, Mboko WP, Bigley TM, Terhune SS, Tarakanova VL.

J Virol. 2013 Jul;87(13):7314-25. doi: 10.1128/JVI.02713-12. Epub 2013 Apr 24. Erratum in: J Virol. 2017 Dec 14;92 (1):.

2.

Primary macrophages rely on histone deacetylase 1 and 2 expression to induce type I interferon in response to gammaherpesvirus infection.

Mounce BC, Mboko WP, Kanack AJ, Tarakanova VL.

J Virol. 2014 Feb;88(4):2268-78. doi: 10.1128/JVI.03278-13. Epub 2013 Dec 11.

3.

Gammaherpesvirus gene expression and DNA synthesis are facilitated by viral protein kinase and histone variant H2AX.

Mounce BC, Tsan FC, Droit L, Kohler S, Reitsma JM, Cirillo LA, Tarakanova VL.

Virology. 2011 Nov 25;420(2):73-81. doi: 10.1016/j.virol.2011.08.019. Epub 2011 Sep 22.

4.

Conserved gammaherpesvirus kinase and histone variant H2AX facilitate gammaherpesvirus latency in vivo.

Tarakanova VL, Stanitsa E, Leonardo SM, Bigley TM, Gauld SB.

Virology. 2010 Sep 15;405(1):50-61. doi: 10.1016/j.virol.2010.05.027. Epub 2010 Jun 16.

5.

MHV68 complement regulatory protein facilitates MHV68 replication in primary macrophages in a complement independent manner.

Tarakanova VL, Molleston JM, Goodwin M, Virgin HW 4th.

Virology. 2010 Jan 20;396(2):323-8. doi: 10.1016/j.virol.2009.10.030. Epub 2009 Nov 11.

6.

Virus-encoded microRNAs facilitate gammaherpesvirus latency and pathogenesis in vivo.

Feldman ER, Kara M, Coleman CB, Grau KR, Oko LM, Krueger BJ, Renne R, van Dyk LF, Tibbetts SA.

MBio. 2014 May 27;5(3):e00981-14. doi: 10.1128/mBio.00981-14.

7.

Identification of alternative transcripts encoding the essential murine gammaherpesvirus lytic transactivator RTA.

Wakeman BS, Johnson LS, Paden CR, Gray KS, Virgin HW, Speck SH.

J Virol. 2014 May;88(10):5474-90. doi: 10.1128/JVI.03110-13. Epub 2014 Feb 26.

8.

Histone deacetylases and the nuclear receptor corepressor regulate lytic-latent switch gene 50 in murine gammaherpesvirus 68-infected macrophages.

Goodwin MM, Molleston JM, Canny S, Abou El Hassan M, Willert EK, Bremner R, Virgin HW.

J Virol. 2010 Nov;84(22):12039-47. doi: 10.1128/JVI.00396-10. Epub 2010 Aug 18.

9.

The murine gammaherpesvirus immediate-early Rta synergizes with IRF4, targeting expression of the viral M1 superantigen to plasma cells.

O'Flaherty BM, Soni T, Wakeman BS, Speck SH.

PLoS Pathog. 2014 Aug 7;10(8):e1004302. doi: 10.1371/journal.ppat.1004302. eCollection 2014 Aug.

10.

The gammaherpesviruses Kaposi's sarcoma-associated herpesvirus and murine gammaherpesvirus 68 modulate the Toll-like receptor-induced proinflammatory cytokine response.

Bussey KA, Reimer E, Todt H, Denker B, Gallo A, Konrad A, Ottinger M, Adler H, St├╝rzl M, Brune W, Brinkmann MM.

J Virol. 2014 Aug;88(16):9245-59. doi: 10.1128/JVI.00841-14. Epub 2014 Jun 4.

11.

Gamma-herpesvirus kinase actively initiates a DNA damage response by inducing phosphorylation of H2AX to foster viral replication.

Tarakanova VL, Leung-Pineda V, Hwang S, Yang CW, Matatall K, Basson M, Sun R, Piwnica-Worms H, Sleckman BP, Virgin HW 4th.

Cell Host Microbe. 2007 Jun 14;1(4):275-86.

12.
13.

Phosphorylation of Kaposi's sarcoma-associated herpesvirus processivity factor ORF59 by a viral kinase modulates its ability to associate with RTA and oriLyt.

McDowell ME, Purushothaman P, Rossetto CC, Pari GS, Verma SC.

J Virol. 2013 Jul;87(14):8038-52. doi: 10.1128/JVI.03460-12. Epub 2013 May 15.

14.

Human cytomegalovirus pUL97 regulates the viral major immediate early promoter by phosphorylation-mediated disruption of histone deacetylase 1 binding.

Bigley TM, Reitsma JM, Mirza SP, Terhune SS.

J Virol. 2013 Jul;87(13):7393-408. doi: 10.1128/JVI.02825-12. Epub 2013 Apr 24.

15.

Human cytomegalovirus UL29/28 protein interacts with components of the NuRD complex which promote accumulation of immediate-early RNA.

Terhune SS, Moorman NJ, Cristea IM, Savaryn JP, Cuevas-Bennett C, Rout MP, Chait BT, Shenk T.

PLoS Pathog. 2010 Jun 24;6(6):e1000965. doi: 10.1371/journal.ppat.1000965.

16.

Alternatively initiated gene 50/RTA transcripts expressed during murine and human gammaherpesvirus reactivation from latency.

Gray KS, Allen RD 3rd, Farrell ML, Forrest JC, Speck SH.

J Virol. 2009 Jan;83(1):314-28. doi: 10.1128/JVI.01444-08. Epub 2008 Oct 29.

17.
18.

The de novo methyltransferases DNMT3a and DNMT3b target the murine gammaherpesvirus immediate-early gene 50 promoter during establishment of latency.

Gray KS, Forrest JC, Speck SH.

J Virol. 2010 May;84(10):4946-59. doi: 10.1128/JVI.00060-10. Epub 2010 Mar 3.

19.

ORF36 protein kinase of Kaposi's sarcoma herpesvirus activates the c-Jun N-terminal kinase signaling pathway.

Hamza MS, Reyes RA, Izumiya Y, Wisdom R, Kung HJ, Luciw PA.

J Biol Chem. 2004 Sep 10;279(37):38325-30. Epub 2004 Jul 5.

20.

Murine Gammaherpesvirus 68 LANA and SOX Homologs Counteract ATM-Driven p53 Activity during Lytic Viral Replication.

Sifford JM, Stahl JA, Salinas E, Forrest JC.

J Virol. 2015 Dec 16;90(5):2571-85. doi: 10.1128/JVI.02867-15.

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