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Items: 1 to 20 of 94

1.

Analysis of heterogeneity in nonspecific PEGylation reactions of biomolecules.

Hakem IF, Leech AM, Bohn J, Walker JP, Bockstaller MR.

Biopolymers. 2013 Jul;99(7):427-35. doi: 10.1002/bip.22193.

PMID:
23616211
2.

Protein carboxyl amidation increases the potential extent of protein polyethylene glycol conjugation.

Li S, Yang Z, Sun X, Tan Y, Yagi S, Hoffman RM.

Anal Biochem. 2004 Jul 15;330(2):264-71.

PMID:
15203332
3.

Site-specific PEGylation of bone morphogenetic protein-2 cysteine analogues.

Hu J, Duppatla V, Harth S, Schmitz W, Sebald W.

Bioconjug Chem. 2010 Oct 20;21(10):1762-72. doi: 10.1021/bc9005706.

PMID:
20886828
4.

Characterization of site-specific ScFv PEGylation for tumor-targeting pharmaceuticals.

Natarajan A, Xiong CY, Albrecht H, DeNardo GL, DeNardo SJ.

Bioconjug Chem. 2005 Jan-Feb;16(1):113-21.

PMID:
15656582
5.

PEG chain length impacts yield of solid-phase protein PEGylation and efficiency of PEGylated protein separation by ion-exchange chromatography: insights of mechanistic models.

Yoshimoto N, Isakari Y, Itoh D, Yamamoto S.

Biotechnol J. 2013 Jul;8(7):801-10. doi: 10.1002/biot.201200325. Epub 2013 Jun 21.

PMID:
23788446
6.

PEGylation of proteins and liposomes: a powerful and flexible strategy to improve the drug delivery.

Milla P, Dosio F, Cattel L.

Curr Drug Metab. 2012 Jan;13(1):105-19. Review.

PMID:
21892917
7.

Obstacles and pitfalls in the PEGylation of therapeutic proteins.

Gaberc-Porekar V, Zore I, Podobnik B, Menart V.

Curr Opin Drug Discov Devel. 2008 Mar;11(2):242-50. Review.

PMID:
18283612
8.

Optimization of random PEGylation reactions by means of high throughput screening.

Maiser B, Dismer F, Hubbuch J.

Biotechnol Bioeng. 2014 Jan;111(1):104-14. doi: 10.1002/bit.25000. Epub 2013 Aug 12.

PMID:
23939788
9.

PEGylation of cytokines and other therapeutic proteins and peptides: the importance of biological optimisation of coupling techniques.

Francis GE, Fisher D, Delgado C, Malik F, Gardiner A, Neale D.

Int J Hematol. 1998 Jul;68(1):1-18. Review.

PMID:
9713164
10.

The impact of PEGylation on biological therapies.

Veronese FM, Mero A.

BioDrugs. 2008;22(5):315-29. Review.

PMID:
18778113
11.

N-terminal specificity of PEGylation of human bone morphogenetic protein-2 at acidic pH.

Hu J, Sebald W.

Int J Pharm. 2011 Jul 15;413(1-2):140-6. doi: 10.1016/j.ijpharm.2011.04.043. Epub 2011 Apr 22.

PMID:
21539904
12.

Purification of pegylated proteins.

Fee CJ, Van Alstine JM.

Methods Biochem Anal. 2011;54:339-62. Review.

PMID:
21954785
13.

Chemical modification of protein A chromatography ligands with polyethylene glycol. I: Effects on IgG adsorption equilibrium, kinetics, and transport.

Weinberg J, Zhang S, Crews G, Carta G, Przybycien T.

J Chromatogr A. 2018 Apr 20;1546:77-88. doi: 10.1016/j.chroma.2018.03.011. Epub 2018 Mar 9.

PMID:
29551236
14.

Characterization of PEGylated biopharmaceutical products by LC/MS and LC/MS/MS.

Huang L, Gough PC.

Methods Mol Biol. 2012;899:351-63. doi: 10.1007/978-1-61779-921-1_22.

PMID:
22735964
16.

Chemical and enzymatic site specific PEGylation of hGH.

da Silva Freitas D, Mero A, Pasut G.

Bioconjug Chem. 2013 Mar 20;24(3):456-63. doi: 10.1021/bc300594y. Epub 2013 Mar 4.

PMID:
23432141
17.
18.

Anti-PEG antibodies in the clinic: Current issues and beyond PEGylation.

Zhang P, Sun F, Liu S, Jiang S.

J Control Release. 2016 Dec 28;244(Pt B):184-193. doi: 10.1016/j.jconrel.2016.06.040. Epub 2016 Jun 28. Review.

19.

Elucidation of PEGylation site with a combined approach of in-source fragmentation and CID MS/MS.

Lu X, Gough PC, DeFelippis MR, Huang L.

J Am Soc Mass Spectrom. 2010 May;21(5):810-8. doi: 10.1016/j.jasms.2010.01.011. Epub 2010 Jan 25.

20.

Self-Assembly PEGylation Retaining Activity (SPRA) Technology via a Host-Guest Interaction Surpassing Conventional PEGylation Methods of Proteins.

Hirotsu T, Higashi T, Abu Hashim II, Misumi S, Wada K, Motoyama K, Arima H.

Mol Pharm. 2017 Feb 6;14(2):368-376. doi: 10.1021/acs.molpharmaceut.6b00678. Epub 2017 Jan 12.

PMID:
28032772

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