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Prx1 modulates the chemosensitivity of lung cancer to docetaxel through suppression of FOXO1-induced apoptosis.

Hwang KE, Park DS, Kim YS, Kim BR, Park SN, Lee MK, Park SH, Yoon KH, Jeong ET, Kim HR.

Int J Oncol. 2013 Jul;43(1):72-8. doi: 10.3892/ijo.2013.1918. Epub 2013 Apr 24.


Elevated prx1 provides resistance to docetaxel, but is not associated with predictive significance in lung cancer.

Hwang KE, Park C, Seol CH, Hwang YR, Hwang JS, Jung JW, Choi KH, Jeong ET, Kim HR.

Tuberc Respir Dis (Seoul). 2013 Aug;75(2):59-66. doi: 10.4046/trd.2013.75.2.59. Epub 2013 Aug 30.


MMP9 activation triggered by epidermal growth factor induced FoxO1 nuclear exclusion in non-small cell lung cancer.

Pei J, Lou Y, Zhong R, Han B.

Tumour Biol. 2014 Jul;35(7):6673-8. doi: 10.1007/s13277-014-1850-z. Epub 2014 Apr 6.


Knockdown of the M2 Isoform of Pyruvate Kinase (PKM2) with shRNA Enhances the Effect of Docetaxel in Human NSCLC Cell Lines In Vitro.

Yuan S, Qiao T, Zhuang X, Chen W, Xing N, Zhang Q.

Yonsei Med J. 2016 Nov;57(6):1312-23. doi: 10.3349/ymj.2016.57.6.1312.


FoxM1 inhibition enhances chemosensitivity of docetaxel-resistant A549 cells to docetaxel via activation of JNK/mitochondrial pathway.

Wang K, Zhu X, Zhang K, Zhu L, Zhou F.

Acta Biochim Biophys Sin (Shanghai). 2016 Sep;48(9):804-9. doi: 10.1093/abbs/gmw072. Epub 2016 Aug 12.


Exisulind-induced apoptosis in a non-small cell lung cancer orthotopic lung tumor model augments docetaxel treatment and contributes to increased survival.

Whitehead CM, Earle KA, Fetter J, Xu S, Hartman T, Chan DC, Zhao TL, Piazza G, Klein-Szanto AJ, Pamukcu R, Alila H, Bunn PA Jr, Thompson WJ.

Mol Cancer Ther. 2003 May;2(5):479-88.


The forkhead transcription factor FOXO1 mediates cisplatin resistance in gastric cancer cells by activating phosphoinositide 3-kinase/Akt pathway.

Park J, Ko YS, Yoon J, Kim MA, Park JW, Kim WH, Choi Y, Kim JH, Cheon Y, Lee BL.

Gastric Cancer. 2014;17(3):423-30. doi: 10.1007/s10120-013-0314-2. Epub 2013 Nov 8.


Fibronectin protects lung cancer cells against docetaxel-induced apoptosis by promoting Src and caspase-8 phosphorylation.

Qin S, Zhang B, Xiao G, Sun X, Li G, Huang G, Gao X, Li X, Wang H, Yang C, Ren H.

Tumour Biol. 2016 Oct;37(10):13509-13520. Epub 2016 Jul 28.


Expression and localization of FOXO1 in non-small cell lung cancer.

Maekawa T, Maniwa Y, Doi T, Nishio W, Yoshimura M, Ohbayashi C, Hayashi Y, Okita Y.

Oncol Rep. 2009 Jul;22(1):57-64.


Protective action of liraglutide in beta cells under lipotoxic stress via PI3K/Akt/FoxO1 pathway.

Shao S, Nie M, Chen C, Chen X, Zhang M, Yuan G, Yu X, Yang Y.

J Cell Biochem. 2014 Jun;115(6):1166-75. doi: 10.1002/jcb.24763.


Knockdown of CABYR-a/b increases chemosensitivity of human non-small cell lung cancer cells through inactivation of Akt.

Qian Z, Li M, Wang R, Xiao Q, Wang J, Li M, He D, Xiao X.

Mol Cancer Res. 2014 Mar;12(3):335-47. doi: 10.1158/1541-7786.MCR-13-0391. Epub 2013 Dec 20.


FOXO1-dependent DNA damage repair is regulated by JNK in lung cancer cells.

Ju Y, Xu T, Zhang H, Yu A.

Int J Oncol. 2014 Apr;44(4):1284-92. doi: 10.3892/ijo.2014.2269. Epub 2014 Jan 21.


KDM6B Elicits Cell Apoptosis by Promoting Nuclear Translocation of FOXO1 in Non-Small Cell Lung Cancer.

Ma J, Wang N, Zhang Y, Wang C, Ge T, Jin H, Deng X, Huo X, Gu D, Ge Z, Chu W, Jiang L, Qin W.

Cell Physiol Biochem. 2015;37(1):201-13. doi: 10.1159/000430345. Epub 2015 Aug 20.


15-Deoxy-Delta12,14-prostaglandin J2 enhances docetaxel anti-tumor activity against A549 and H460 non-small-cell lung cancer cell lines and xenograft tumors.

Fulzele SV, Chatterjee A, Shaik MS, Jackson T, Ichite N, Singh M.

Anticancer Drugs. 2007 Jan;18(1):65-78.


The 3p21.3 tumor suppressor RBM5 resensitizes cisplatin-resistant human non-small cell lung cancer cells to cisplatin.

Li P, Wang K, Zhang J, Zhao L, Liang H, Shao C, Sutherland LC.

Cancer Epidemiol. 2012 Oct;36(5):481-9. doi: 10.1016/j.canep.2012.04.004. Epub 2012 May 18.


[Sequence-dependent effect of docetaxel with gefitinib on the proliferation and signal protein expression of human lung adenocarcinoma cell SPC-A1].

Zhang W, Zhang W, Wang L, Zheng J, Xiao F.

Zhongguo Fei Ai Za Zhi. 2011 May;14(5):385-90. doi: 10.3779/j.issn.1009-3419.2011.05.01. Chinese.


NFV, an HIV-1 protease inhibitor, induces growth arrest, reduced Akt signalling, apoptosis and docetaxel sensitisation in NSCLC cell lines.

Yang Y, Ikezoe T, Nishioka C, Bandobashi K, Takeuchi T, Adachi Y, Kobayashi M, Takeuchi S, Koeffler HP, Taguchi H.

Br J Cancer. 2006 Dec 18;95(12):1653-62. Epub 2006 Nov 28.


Targeting the Vav3 oncogene enhances docetaxel-induced apoptosis through the inhibition of androgen receptor phosphorylation in LNCaP prostate cancer cells under chronic hypoxia.

Nomura T, Yamasaki M, Hirai K, Inoue T, Sato R, Matsuura K, Moriyama M, Sato F, Mimata H.

Mol Cancer. 2013 Apr 8;12:27. doi: 10.1186/1476-4598-12-27.

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