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Items: 1 to 20 of 89

1.

Single tryptophan of disordered loop from Plasmodium falciparum purine nucleoside phosphorylase: involvement in catalysis and microenvironment.

Suthar MK, Verma A, Doharey PK, Singh SV, Saxena JK.

Appl Biochem Biotechnol. 2013 Jun;170(4):868-79. doi: 10.1007/s12010-013-0228-9. Epub 2013 Apr 25.

PMID:
23615735
2.

Expression of human malaria parasite purine nucleoside phosphorylase in host enzyme-deficient erythrocyte culture. Enzyme characterization and identification of novel inhibitors.

Daddona PE, Wiesmann WP, Milhouse W, Chern JW, Townsend LB, Hershfield MS, Webster HK.

J Biol Chem. 1986 Sep 5;261(25):11667-73.

3.

Behavior of Plasmodium falciparum purine nucleoside phosphorylase in macromolecular crowded environment.

Suthar MK, Doharey PK, Verma A, Saxena JK.

Int J Biol Macromol. 2013 Nov;62:657-62. doi: 10.1016/j.ijbiomac.2013.09.036. Epub 2013 Oct 1.

PMID:
24095713
4.

Transition state analogue inhibitors of purine nucleoside phosphorylase from Plasmodium falciparum.

Kicska GA, Tyler PC, Evans GB, Furneaux RH, Kim K, Schramm VL.

J Biol Chem. 2002 Feb 1;277(5):3219-25. Epub 2001 Nov 13.

5.

Structures of Plasmodium falciparum purine nucleoside phosphorylase complexed with sulfate and its natural substrate inosine.

Schnick C, Robien MA, Brzozowski AM, Dodson EJ, Murshudov GN, Anderson L, Luft JR, Mehlin C, Hol WG, Brannigan JA, Wilkinson AJ.

Acta Crystallogr D Biol Crystallogr. 2005 Sep;61(Pt 9):1245-54. Epub 2005 Aug 16.

PMID:
16131758
6.

Plasmodium falciparum purine nucleoside phosphorylase: crystal structures, immucillin inhibitors, and dual catalytic function.

Shi W, Ting LM, Kicska GA, Lewandowicz A, Tyler PC, Evans GB, Furneaux RH, Kim K, Almo SC, Schramm VL.

J Biol Chem. 2004 Apr 30;279(18):18103-6. Epub 2004 Feb 23.

7.

Transition state analysis for human and Plasmodium falciparum purine nucleoside phosphorylases.

Lewandowicz A, Schramm VL.

Biochemistry. 2004 Feb 17;43(6):1458-68.

PMID:
14769022
8.
9.

Structural determinants of the 5'-methylthioinosine specificity of Plasmodium purine nucleoside phosphorylase.

Donaldson TM, Ting LM, Zhan C, Shi W, Zheng R, Almo SC, Kim K.

PLoS One. 2014 Jan 8;9(1):e84384. doi: 10.1371/journal.pone.0084384. eCollection 2014.

10.
11.

Energetic mapping of transition state analogue interactions with human and Plasmodium falciparum purine nucleoside phosphorylases.

Lewandowicz A, Ringia EA, Ting LM, Kim K, Tyler PC, Evans GB, Zubkova OV, Mee S, Painter GF, Lenz DH, Furneaux RH, Schramm VL.

J Biol Chem. 2005 Aug 26;280(34):30320-8. Epub 2005 Jun 16.

12.

Plasmodium falciparum purine nucleoside phosphorylase is critical for viability of malaria parasites.

Madrid DC, Ting LM, Waller KL, Schramm VL, Kim K.

J Biol Chem. 2008 Dec 19;283(51):35899-907. doi: 10.1074/jbc.M807218200. Epub 2008 Oct 28.

13.

Conservation of structure and activity in Plasmodium purine nucleoside phosphorylases.

Chaikuad A, Brady RL.

BMC Struct Biol. 2009 Jul 3;9:42. doi: 10.1186/1472-6807-9-42.

14.

Tryptophan-free human PNP reveals catalytic site interactions.

Ghanem M, Saen-oon S, Zhadin N, Wing C, Cahill SM, Schwartz SD, Callender R, Schramm VL.

Biochemistry. 2008 Mar 11;47(10):3202-15. doi: 10.1021/bi702491d. Epub 2008 Feb 13.

PMID:
18269249
15.

Structural analyses reveal two distinct families of nucleoside phosphorylases.

Pugmire MJ, Ealick SE.

Biochem J. 2002 Jan 1;361(Pt 1):1-25. Review.

16.

Purine-less death in Plasmodium falciparum induced by immucillin-H, a transition state analogue of purine nucleoside phosphorylase.

Kicska GA, Tyler PC, Evans GB, Furneaux RH, Schramm VL, Kim K.

J Biol Chem. 2002 Feb 1;277(5):3226-31. Epub 2001 Nov 12.

17.

Isolation and functional characterization of the PfNT1 nucleoside transporter gene from Plasmodium falciparum.

Carter NS, Ben Mamoun C, Liu W, Silva EO, Landfear SM, Goldberg DE, Ullman B.

J Biol Chem. 2000 Apr 7;275(14):10683-91.

18.

Targeting a novel Plasmodium falciparum purine recycling pathway with specific immucillins.

Ting LM, Shi W, Lewandowicz A, Singh V, Mwakingwe A, Birck MR, Ringia EA, Bench G, Madrid DC, Tyler PC, Evans GB, Furneaux RH, Schramm VL, Kim K.

J Biol Chem. 2005 Mar 11;280(10):9547-54. Epub 2004 Dec 2.

19.
20.

Evolutionary and mechanistic insights into substrate and product accommodation of CTP:phosphocholine cytidylyltransferase from Plasmodium falciparum.

Nagy GN, Marton L, Krámos B, Oláh J, Révész Á, Vékey K, Delsuc F, Hunyadi-Gulyás É, Medzihradszky KF, Lavigne M, Vial H, Cerdan R, Vértessy BG.

FEBS J. 2013 Jul;280(13):3132-48. doi: 10.1111/febs.12282. Epub 2013 May 24.

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