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Items: 1 to 20 of 65

1.

The tyrosine phosphatase PTPN14 is a negative regulator of YAP activity.

Michaloglou C, Lehmann W, Martin T, Delaunay C, Hueber A, Barys L, Niu H, Billy E, Wartmann M, Ito M, Wilson CJ, Digan ME, Bauer A, Voshol H, Christofori G, Sellers WR, Hofmann F, Schmelzle T.

PLoS One. 2013 Apr 16;8(4):e61916. doi: 10.1371/journal.pone.0061916. Print 2013.

2.

PTPN14 forms a complex with Kibra and LATS1 proteins and negatively regulates the YAP oncogenic function.

Wilson KE, Li YW, Yang N, Shen H, Orillion AR, Zhang J.

J Biol Chem. 2014 Aug 22;289(34):23693-700. doi: 10.1074/jbc.M113.534701. Epub 2014 Jul 14.

3.

PTPN14 interacts with and negatively regulates the oncogenic function of YAP.

Liu X, Yang N, Figel SA, Wilson KE, Morrison CD, Gelman IH, Zhang J.

Oncogene. 2013 Mar 7;32(10):1266-73. doi: 10.1038/onc.2012.147. Epub 2012 Apr 23.

4.

YAP modifies cancer cell sensitivity to EGFR and survivin inhibitors and is negatively regulated by the non-receptor type protein tyrosine phosphatase 14.

Huang JM, Nagatomo I, Suzuki E, Mizuno T, Kumagai T, Berezov A, Zhang H, Karlan B, Greene MI, Wang Q.

Oncogene. 2013 Apr 25;32(17):2220-9. doi: 10.1038/onc.2012.231. Epub 2012 Jun 11.

5.

The PDZ-binding motif of Yes-associated protein is required for its co-activation of TEAD-mediated CTGF transcription and oncogenic cell transforming activity.

Shimomura T, Miyamura N, Hata S, Miura R, Hirayama J, Nishina H.

Biochem Biophys Res Commun. 2014 Jan 17;443(3):917-23. doi: 10.1016/j.bbrc.2013.12.100. Epub 2013 Dec 28.

PMID:
24380865
6.

PTPN14 is required for the density-dependent control of YAP1.

Wang W, Huang J, Wang X, Yuan J, Li X, Feng L, Park JI, Chen J.

Genes Dev. 2012 Sep 1;26(17):1959-71. doi: 10.1101/gad.192955.112.

7.

The p130 isoform of angiomotin is required for Yap-mediated hepatic epithelial cell proliferation and tumorigenesis.

Yi C, Shen Z, Stemmer-Rachamimov A, Dawany N, Troutman S, Showe LC, Liu Q, Shimono A, Sudol M, Holmgren L, Stanger BZ, Kissil JL.

Sci Signal. 2013 Sep 3;6(291):ra77. doi: 10.1126/scisignal.2004060.

8.

Both TEAD-binding and WW domains are required for the growth stimulation and oncogenic transformation activity of yes-associated protein.

Zhao B, Kim J, Ye X, Lai ZC, Guan KL.

Cancer Res. 2009 Feb 1;69(3):1089-98. doi: 10.1158/0008-5472.CAN-08-2997. Epub 2009 Jan 13.

9.

Hippo pathway-independent restriction of TAZ and YAP by angiomotin.

Chan SW, Lim CJ, Chong YF, Pobbati AV, Huang C, Hong W.

J Biol Chem. 2011 Mar 4;286(9):7018-26. doi: 10.1074/jbc.C110.212621. Epub 2011 Jan 11.

10.

The Hippo pathway target, YAP, promotes metastasis through its TEAD-interaction domain.

Lamar JM, Stern P, Liu H, Schindler JW, Jiang ZG, Hynes RO.

Proc Natl Acad Sci U S A. 2012 Sep 11;109(37):E2441-50. doi: 10.1073/pnas.1212021109. Epub 2012 Aug 13.

11.

E-cadherin mediates contact inhibition of proliferation through Hippo signaling-pathway components.

Kim NG, Koh E, Chen X, Gumbiner BM.

Proc Natl Acad Sci U S A. 2011 Jul 19;108(29):11930-5. doi: 10.1073/pnas.1103345108. Epub 2011 Jul 5.

12.

Targeting YAP and Hippo signaling pathway in liver cancer.

Liu AM, Xu MZ, Chen J, Poon RT, Luk JM.

Expert Opin Ther Targets. 2010 Aug;14(8):855-68. doi: 10.1517/14728222.2010.499361. Review.

PMID:
20545481
13.

Dual function of Yap in the regulation of lens progenitor cells and cellular polarity.

Song JY, Park R, Kim JY, Hughes L, Lu L, Kim S, Johnson RL, Cho SH.

Dev Biol. 2014 Feb 15;386(2):281-90. doi: 10.1016/j.ydbio.2013.12.037. Epub 2013 Dec 31.

14.

Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control.

Zhao B, Wei X, Li W, Udan RS, Yang Q, Kim J, Xie J, Ikenoue T, Yu J, Li L, Zheng P, Ye K, Chinnaiyan A, Halder G, Lai ZC, Guan KL.

Genes Dev. 2007 Nov 1;21(21):2747-61.

15.

Transforming properties of YAP, a candidate oncogene on the chromosome 11q22 amplicon.

Overholtzer M, Zhang J, Smolen GA, Muir B, Li W, Sgroi DC, Deng CX, Brugge JS, Haber DA.

Proc Natl Acad Sci U S A. 2006 Aug 15;103(33):12405-10. Epub 2006 Aug 7.

16.

A WW domain-containing yes-associated protein (YAP) is a novel transcriptional co-activator.

Yagi R, Chen LF, Shigesada K, Murakami Y, Ito Y.

EMBO J. 1999 May 4;18(9):2551-62.

17.
18.

Transcriptional output of the Salvador/warts/hippo pathway is controlled in distinct fashions in Drosophila melanogaster and mammalian cell lines.

Zhang X, Milton CC, Humbert PO, Harvey KF.

Cancer Res. 2009 Aug 1;69(15):6033-41. doi: 10.1158/0008-5472.CAN-08-4592. Epub 2009 Jul 7.

19.

The Hippo pathway and apico-basal cell polarity.

Genevet A, Tapon N.

Biochem J. 2011 Jun 1;436(2):213-24. doi: 10.1042/BJ20110217. Review.

PMID:
21568941
20.

TEAD mediates YAP-dependent gene induction and growth control.

Zhao B, Ye X, Yu J, Li L, Li W, Li S, Yu J, Lin JD, Wang CY, Chinnaiyan AM, Lai ZC, Guan KL.

Genes Dev. 2008 Jul 15;22(14):1962-71. doi: 10.1101/gad.1664408. Epub 2008 Jun 25.

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