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Items: 1 to 20 of 70

1.

PAK1 protein expression in the auditory cortex of schizophrenia subjects.

Deo AJ, Goldszer IM, Li S, DiBitetto JV, Henteleff R, Sampson A, Lewis DA, Penzes P, Sweet RA.

PLoS One. 2013 Apr 22;8(4):e59458. doi: 10.1371/journal.pone.0059458. Print 2013.

PMID:
23613712
2.

Abnormalities of the Duo/Ras-related C3 botulinum toxin substrate 1/p21-activated kinase 1 pathway drive myosin light chain phosphorylation in frontal cortex in schizophrenia.

Rubio MD, Haroutunian V, Meador-Woodruff JH.

Biol Psychiatry. 2012 May 15;71(10):906-14. doi: 10.1016/j.biopsych.2012.02.006. Epub 2012 Mar 27.

PMID:
22458949
3.

Altered expression of CDC42 signaling pathway components in cortical layer 3 pyramidal cells in schizophrenia.

Datta D, Arion D, Corradi JP, Lewis DA.

Biol Psychiatry. 2015 Dec 1;78(11):775-85. doi: 10.1016/j.biopsych.2015.03.030. Epub 2015 Apr 11.

PMID:
25981171
4.

Molecular mechanisms contributing to dendritic spine alterations in the prefrontal cortex of subjects with schizophrenia.

Hill JJ, Hashimoto T, Lewis DA.

Mol Psychiatry. 2006 Jun;11(6):557-66.

PMID:
16402129
5.

Increased expression of Kalirin-9 in the auditory cortex of schizophrenia subjects: its role in dendritic pathology.

Deo AJ, Cahill ME, Li S, Goldszer I, Henteleff R, Vanleeuwen JE, Rafalovich I, Gao R, Stachowski EK, Sampson AR, Lewis DA, Penzes P, Sweet RA.

Neurobiol Dis. 2012 Feb;45(2):796-803. doi: 10.1016/j.nbd.2011.11.003. Epub 2011 Nov 13.

PMID:
22120753
6.

Involvement of alpha-PAK-interacting exchange factor in the PAK1-c-Jun NH(2)-terminal kinase 1 activation and apoptosis induced by benzo[a]pyrene.

Yoshii S, Tanaka M, Otsuki Y, Fujiyama T, Kataoka H, Arai H, Hanai H, Sugimura H.

Mol Cell Biol. 2001 Oct;21(20):6796-807.

PMID:
11564864
7.

The p21-activated kinase PAK3 forms heterodimers with PAK1 in brain implementing trans-regulation of PAK3 activity.

Combeau G, Kreis P, Domenichini F, Amar M, Fossier P, Rousseau V, Barnier JV.

J Biol Chem. 2012 Aug 31;287(36):30084-96. doi: 10.1074/jbc.M112.355073. Epub 2012 Jul 19.

PMID:
22815483
8.

alphaPix stimulates p21-activated kinase activity through exchange factor-dependent and -independent mechanisms.

Daniels RH, Zenke FT, Bokoch GM.

J Biol Chem. 1999 Mar 5;274(10):6047-50. Erratum in: J Biol Chem 1999 May 21;274(21):15292.

PMID:
10037684
9.

Directional sensing requires G beta gamma-mediated PAK1 and PIX alpha-dependent activation of Cdc42.

Li Z, Hannigan M, Mo Z, Liu B, Lu W, Wu Y, Smrcka AV, Wu G, Li L, Liu M, Huang CK, Wu D.

Cell. 2003 Jul 25;114(2):215-27.

PMID:
12887923
10.

Intracortical excitatory and thalamocortical boutons are intact in primary auditory cortex in schizophrenia.

Moyer CE, Delevich KM, Fish KN, Asafu-Adjei JK, Sampson AR, Dorph-Petersen KA, Lewis DA, Sweet RA.

Schizophr Res. 2013 Sep;149(1-3):127-34. doi: 10.1016/j.schres.2013.06.024. Epub 2013 Jul 2.

PMID:
23830684
11.

Pak1 and PIX regulate contact inhibition during epithelial wound healing.

Zegers MM, Forget MA, Chernoff J, Mostov KE, ter Beest MB, Hansen SH.

EMBO J. 2003 Aug 15;22(16):4155-65.

PMID:
12912914
12.
13.

Reduced glutamate decarboxylase 65 protein within primary auditory cortex inhibitory boutons in schizophrenia.

Moyer CE, Delevich KM, Fish KN, Asafu-Adjei JK, Sampson AR, Dorph-Petersen KA, Lewis DA, Sweet RA.

Biol Psychiatry. 2012 Nov 1;72(9):734-43. doi: 10.1016/j.biopsych.2012.04.010. Epub 2012 May 23.

PMID:
22624794
14.

Adhesion stimulates direct PAK1/ERK2 association and leads to ERK-dependent PAK1 Thr212 phosphorylation.

Sundberg-Smith LJ, Doherty JT, Mack CP, Taylor JM.

J Biol Chem. 2005 Jan 21;280(3):2055-64. Epub 2004 Nov 12.

PMID:
15542607
15.
16.

Altered glutamate protein co-expression network topology linked to spine loss in the auditory cortex of schizophrenia.

MacDonald ML, Ding Y, Newman J, Hemby S, Penzes P, Lewis DA, Yates NA, Sweet RA.

Biol Psychiatry. 2015 Jun 1;77(11):959-68. doi: 10.1016/j.biopsych.2014.09.006. Epub 2014 Nov 26.

PMID:
25433904
17.

Abnormal kalirin signaling in neuropsychiatric disorders.

Remmers C, Sweet RA, Penzes P.

Brain Res Bull. 2014 Apr;103:29-38. doi: 10.1016/j.brainresbull.2013.12.006. Epub 2013 Dec 12. Review.

PMID:
24334022
18.

A PAK1-PIX-PKL complex is activated by the T-cell receptor independent of Nck, Slp-76 and LAT.

Ku GM, Yablonski D, Manser E, Lim L, Weiss A.

EMBO J. 2001 Feb 1;20(3):457-65.

PMID:
11157752
19.

Autophosphorylation-dependent degradation of Pak1, triggered by the Rho-family GTPase, Chp.

Weisz Hubsman M, Volinsky N, Manser E, Yablonski D, Aronheim A.

Biochem J. 2007 Jun 15;404(3):487-97.

PMID:
17355222
20.

Modulation of p21-activated kinase 1 alters the behavior of renal cell carcinoma.

O'Sullivan GC, Tangney M, Casey G, Ambrose M, Houston A, Barry OP.

Int J Cancer. 2007 Nov 1;121(9):1930-40.

PMID:
17621631

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