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Items: 1 to 20 of 639

1.

Effect of the STAT3 inhibitor STX-0119 on the proliferation of cancer stem-like cells derived from recurrent glioblastoma.

Ashizawa T, Miyata H, Iizuka A, Komiyama M, Oshita C, Kume A, Nogami M, Yagoto M, Ito I, Oishi T, Watanabe R, Mitsuya K, Matsuno K, Furuya T, Okawara T, Otsuka M, Ogo N, Asai A, Nakasu Y, Yamaguchi K, Akiyama Y.

Int J Oncol. 2013 Jul;43(1):219-27. doi: 10.3892/ijo.2013.1916. Epub 2013 Apr 23.

PMID:
23612755
2.

Antitumor activity of a novel small molecule STAT3 inhibitor against a human lymphoma cell line with high STAT3 activation.

Ashizawa T, Miyata H, Ishii H, Oshita C, Matsuno K, Masuda Y, Furuya T, Okawara T, Otsuka M, Ogo N, Asai A, Akiyama Y.

Int J Oncol. 2011 May;38(5):1245-52. doi: 10.3892/ijo.2011.957. Epub 2011 Feb 28.

PMID:
21369699
3.

Effect of the STAT3 inhibitor STX-0119 on the proliferation of a temozolomide-resistant glioblastoma cell line.

Ashizawa T, Akiyama Y, Miyata H, Iizuka A, Komiyama M, Kume A, Omiya M, Sugino T, Asai A, Hayashi N, Mitsuya K, Nakasu Y, Yamaguchi K.

Int J Oncol. 2014 Jul;45(1):411-8. doi: 10.3892/ijo.2014.2439. Epub 2014 May 12.

PMID:
24820265
4.

On-target JAK2/STAT3 inhibition slows disease progression in orthotopic xenografts of human glioblastoma brain tumor stem cells.

Stechishin OD, Luchman HA, Ruan Y, Blough MD, Nguyen SA, Kelly JJ, Cairncross JG, Weiss S.

Neuro Oncol. 2013 Feb;15(2):198-207. doi: 10.1093/neuonc/nos302. Epub 2012 Dec 21.

5.

Resveratrol suppresses tumorigenicity and enhances radiosensitivity in primary glioblastoma tumor initiating cells by inhibiting the STAT3 axis.

Yang YP, Chang YL, Huang PI, Chiou GY, Tseng LM, Chiou SH, Chen MH, Chen MT, Shih YH, Chang CH, Hsu CC, Ma HI, Wang CT, Tsai LL, Yu CC, Chang CJ.

J Cell Physiol. 2012 Mar;227(3):976-93. doi: 10.1002/jcp.22806.

PMID:
21503893
6.

STAT3 as a Therapeutic Target for Glioblastoma.

Liu Y, Li C, Lin J.

Anticancer Agents Med Chem. 2010 Sep;10(7):512-9. Review.

PMID:
20879983
7.

STAT3 is required for proliferation and maintenance of multipotency in glioblastoma stem cells.

Sherry MM, Reeves A, Wu JK, Cochran BH.

Stem Cells. 2009 Oct;27(10):2383-92. doi: 10.1002/stem.185.

8.

Tanshinone IIA inhibits the growth, attenuates the stemness and induces the apoptosis of human glioma stem cells.

Yang L, Guo H, Dong L, Wang L, Liu C, Wang X.

Oncol Rep. 2014 Sep;32(3):1303-11. doi: 10.3892/or.2014.3293. Epub 2014 Jun 26.

PMID:
24970314
9.

Cardamonin induces apoptosis by suppressing STAT3 signaling pathway in glioblastoma stem cells.

Wu N, Liu J, Zhao X, Yan Z, Jiang B, Wang L, Cao S, Shi D, Lin X.

Tumour Biol. 2015 Dec;36(12):9667-76. doi: 10.1007/s13277-015-3673-y. Epub 2015 Jul 7.

PMID:
26150336
10.

Cyclopamine cooperates with EGFR inhibition to deplete stem-like cancer cells in glioblastoma-derived spheroid cultures.

Eimer S, Dugay F, Airiau K, Avril T, Quillien V, Belaud-Rotureau MA, Belloc F.

Neuro Oncol. 2012 Dec;14(12):1441-51. doi: 10.1093/neuonc/nos266. Epub 2012 Oct 26.

11.
12.

The interference of Notch1 target Hes1 affects cell growth, differentiation and invasiveness of glioblastoma stem cells through modulation of multiple oncogenic targets.

Cenciarelli C, Marei HE, Zonfrillo M, Casalbore P, Felsani A, Giannetti S, Trevisi G, Althani A, Mangiola A.

Oncotarget. 2017 Mar 14;8(11):17873-17886. doi: 10.18632/oncotarget.15013.

13.

Blockade of TGF-β signaling by the TGFβR-I kinase inhibitor LY2109761 enhances radiation response and prolongs survival in glioblastoma.

Zhang M, Kleber S, Röhrich M, Timke C, Han N, Tuettenberg J, Martin-Villalba A, Debus J, Peschke P, Wirkner U, Lahn M, Huber PE.

Cancer Res. 2011 Dec 1;71(23):7155-67. doi: 10.1158/0008-5472.CAN-11-1212. Epub 2011 Oct 17.

14.

Molecular heterogeneity in a patient-derived glioblastoma xenoline is regulated by different cancer stem cell populations.

Garner JM, Ellison DW, Finkelstein D, Ganguly D, Du Z, Sims M, Yang CH, Interiano RB, Davidoff AM, Pfeffer LM.

PLoS One. 2015 May 8;10(5):e0125838. doi: 10.1371/journal.pone.0125838. eCollection 2015. Erratum in: PLoS One. 2015;10(12):e0145052.

15.

Induction of cell-cycle arrest and apoptosis in glioblastoma stem-like cells by WP1193, a novel small molecule inhibitor of the JAK2/STAT3 pathway.

Sai K, Wang S, Balasubramaniyan V, Conrad C, Lang FF, Aldape K, Szymanski S, Fokt I, Dasgupta A, Madden T, Guan S, Chen Z, Alfred Yung WK, Priebe W, Colman H.

J Neurooncol. 2012 May;107(3):487-501. doi: 10.1007/s11060-011-0786-z. Epub 2012 Jan 17.

PMID:
22249692
16.

Effect of the JAK2/STAT3 inhibitor SAR317461 on human glioblastoma tumorspheres.

Mukthavaram R, Ouyang X, Saklecha R, Jiang P, Nomura N, Pingle SC, Guo F, Makale M, Kesari S.

J Transl Med. 2015 Aug 18;13:269. doi: 10.1186/s12967-015-0627-5.

17.

The small molecule, LLL12, inhibits STAT3 phosphorylation and induces apoptosis in medulloblastoma and glioblastoma cells.

Ball S, Li C, Li PK, Lin J.

PLoS One. 2011 Apr 19;6(4):e18820. doi: 10.1371/journal.pone.0018820.

18.

TRIM8 regulates stemness in glioblastoma through PIAS3-STAT3.

Zhang C, Mukherjee S, Tucker-Burden C, Ross JL, Chau MJ, Kong J, Brat DJ.

Mol Oncol. 2017 Mar;11(3):280-294. doi: 10.1002/1878-0261.12034. Epub 2017 Feb 15.

19.

NOTCH pathway blockade depletes CD133-positive glioblastoma cells and inhibits growth of tumor neurospheres and xenografts.

Fan X, Khaki L, Zhu TS, Soules ME, Talsma CE, Gul N, Koh C, Zhang J, Li YM, Maciaczyk J, Nikkhah G, Dimeco F, Piccirillo S, Vescovi AL, Eberhart CG.

Stem Cells. 2010 Jan;28(1):5-16. doi: 10.1002/stem.254.

20.

STAT3 is essential for the maintenance of neurosphere-initiating tumor cells in patients with glioblastomas: a potential for targeted therapy?

Villalva C, Martin-Lannerée S, Cortes U, Dkhissi F, Wager M, Le Corf A, Tourani JM, Dusanter-Fourt I, Turhan AG, Karayan-Tapon L.

Int J Cancer. 2011 Feb 15;128(4):826-38. doi: 10.1002/ijc.25416.

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