Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 103

1.

Human UDP-glucuronosyltransferase (UGT) 2B10 in drug N-glucuronidation: substrate screening and comparison with UGT1A3 and UGT1A4.

Kato Y, Izukawa T, Oda S, Fukami T, Finel M, Yokoi T, Nakajima M.

Drug Metab Dispos. 2013 Jul;41(7):1389-97. doi: 10.1124/dmd.113.051565. Epub 2013 Apr 23.

2.

Role of human UGT2B10 in N-glucuronidation of tricyclic antidepressants, amitriptyline, imipramine, clomipramine, and trimipramine.

Zhou D, Guo J, Linnenbach AJ, Booth-Genthe CL, Grimm SW.

Drug Metab Dispos. 2010 May;38(5):863-70. doi: 10.1124/dmd.109.030981. Epub 2010 Feb 4.

3.

Regio- and stereospecific N-glucuronidation of medetomidine: the differences between UDP glucuronosyltransferase (UGT) 1A4 and UGT2B10 account for the complex kinetics of human liver microsomes.

Kaivosaari S, Toivonen P, Aitio O, Sipilä J, Koskinen M, Salonen JS, Finel M.

Drug Metab Dispos. 2008 Aug;36(8):1529-37. doi: 10.1124/dmd.108.021709. Epub 2008 May 12.

4.

Nicotine glucuronidation and the human UDP-glucuronosyltransferase UGT2B10.

Kaivosaari S, Toivonen P, Hesse LM, Koskinen M, Court MH, Finel M.

Mol Pharmacol. 2007 Sep;72(3):761-8. Epub 2007 Jun 18.

5.

Glucuronidation of amines and other xenobiotics catalyzed by expressed human UDP-glucuronosyltransferase 1A3.

Green MD, King CD, Mojarrabi B, Mackenzie PI, Tephly TR.

Drug Metab Dispos. 1998 Jun;26(6):507-12.

6.
7.

Influence of N-terminal domain histidine and proline residues on the substrate selectivities of human UDP-glucuronosyltransferase 1A1, 1A6, 1A9, 2B7, and 2B10.

Kerdpin O, Mackenzie PI, Bowalgaha K, Finel M, Miners JO.

Drug Metab Dispos. 2009 Sep;37(9):1948-55. doi: 10.1124/dmd.109.028225. Epub 2009 Jun 1.

8.

Imipramine N-glucuronidation in human liver microsomes: biphasic kinetics and characterization of UDP-glucuronosyltransferase isoforms.

Nakajima M, Tanaka E, Kobayashi T, Ohashi N, Kume T, Yokoi T.

Drug Metab Dispos. 2002 Jun;30(6):636-42.

10.

Critical roles of residues 36 and 40 in the phenol and tertiary amine aglycone substrate selectivities of UDP-glucuronosyltransferases 1A3 and 1A4.

Kubota T, Lewis BC, Elliot DJ, Mackenzie PI, Miners JO.

Mol Pharmacol. 2007 Oct;72(4):1054-62. Epub 2007 Jul 17.

11.

Olanzapine metabolism and the significance of UGT1A448V and UGT2B1067Y variants.

Erickson-Ridout KK, Zhu J, Lazarus P.

Pharmacogenet Genomics. 2011 Sep;21(9):539-51. doi: 10.1097/FPC.0b013e328348c76b.

PMID:
21750471
12.

Glucuronidation of tobacco-specific nitrosamines by UGT2B10.

Chen G, Dellinger RW, Sun D, Spratt TE, Lazarus P.

Drug Metab Dispos. 2008 May;36(5):824-30. doi: 10.1124/dmd.107.019406. Epub 2008 Jan 31.

14.

N-glucuronidation catalyzed by UGT1A4 and UGT2B10 in human liver microsomes: Assay optimization and substrate identification.

Lu D, Xie Q, Wu B.

J Pharm Biomed Anal. 2017 Oct 25;145:692-703. doi: 10.1016/j.jpba.2017.07.037. Epub 2017 Aug 4.

PMID:
28803208
15.

Characterization of rabbit UDP-glucuronosyltransferase UGT1A7: tertiary amine glucuronidation is catalyzed by UGT1A7 and UGT1A4.

Bruck M, Li Q, Lamb JG, Tukey RH.

Arch Biochem Biophys. 1997 Dec 15;348(2):357-64.

PMID:
9463278
16.

Characterization of rabbit UDP-glucuronosyltransferase UGT1A7: tertiary amine glucuronidation is catalyzed by UGT1A7 and UGT1A4.

Bruck M, Li Q, Lamb JG, Tukey RH.

Arch Biochem Biophys. 1997 Aug 15;344(2):357-64. Corrected and republished in: Arch Biochem Biophys. 1997 Dec 15;348(2):357-64.

PMID:
9264550
17.

Cloning and expression of human UDP-glucuronosyltransferase 1A4 in Bac-to-Bac system.

Qian M, Chen S, Li X, Zeng S.

Biochem Biophys Res Commun. 2004 Jun 25;319(2):386-92.

PMID:
15178418
19.

N-glucuronidation of drugs and other xenobiotics by human and animal UDP-glucuronosyltransferases.

Kaivosaari S, Finel M, Koskinen M.

Xenobiotica. 2011 Aug;41(8):652-69. doi: 10.3109/00498254.2011.563327. Epub 2011 Mar 24. Review.

PMID:
21434773

Supplemental Content

Support Center