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Items: 1 to 20 of 142

1.

Large lateral movement of transmembrane helix S5 is not required for substrate access to the active site of rhomboid intramembrane protease.

Xue Y, Ha Y.

J Biol Chem. 2013 Jun 7;288(23):16645-54. doi: 10.1074/jbc.M112.438127. Epub 2013 Apr 22.

2.

Structural analysis of a rhomboid family intramembrane protease reveals a gating mechanism for substrate entry.

Wu Z, Yan N, Feng L, Oberstein A, Yan H, Baker RP, Gu L, Jeffrey PD, Urban S, Shi Y.

Nat Struct Mol Biol. 2006 Dec;13(12):1084-91. Epub 2006 Nov 10.

PMID:
17099694
3.

Enzymatic analysis of a rhomboid intramembrane protease implicates transmembrane helix 5 as the lateral substrate gate.

Baker RP, Young K, Feng L, Shi Y, Urban S.

Proc Natl Acad Sci U S A. 2007 May 15;104(20):8257-62. Epub 2007 Apr 26.

4.
5.

Substrate binding and specificity of rhomboid intramembrane protease revealed by substrate-peptide complex structures.

Zoll S, Stanchev S, Began J, Skerle J, Lepšík M, Peclinovská L, Majer P, Strisovsky K.

EMBO J. 2014 Oct 16;33(20):2408-21. doi: 10.15252/embj.201489367. Epub 2014 Sep 12.

6.

Structure and mechanism of rhomboid protease.

Ha Y, Akiyama Y, Xue Y.

J Biol Chem. 2013 May 31;288(22):15430-6. doi: 10.1074/jbc.R112.422378. Epub 2013 Apr 12. Review.

7.

Crystal structure of a rhomboid family intramembrane protease.

Wang Y, Zhang Y, Ha Y.

Nature. 2006 Nov 9;444(7116):179-80. Epub 2006 Oct 11.

PMID:
17051161
8.

Domain swapping in the cytoplasmic domain of the Escherichia coli rhomboid protease.

Lazareno-Saez C, Arutyunova E, Coquelle N, Lemieux MJ.

J Mol Biol. 2013 Apr 12;425(7):1127-42. doi: 10.1016/j.jmb.2013.01.019. Epub 2013 Jan 23.

PMID:
23353827
9.

An internal water-retention site in the rhomboid intramembrane protease GlpG ensures catalytic efficiency.

Zhou Y, Moin SM, Urban S, Zhang Y.

Structure. 2012 Jul 3;20(7):1255-63. doi: 10.1016/j.str.2012.04.022. Epub 2012 Jun 14.

10.

Untangling structure-function relationships in the rhomboid family of intramembrane proteases.

Brooks CL, Lemieux MJ.

Biochim Biophys Acta. 2013 Dec;1828(12):2862-72. doi: 10.1016/j.bbamem.2013.05.003. Review.

11.

Open-cap conformation of intramembrane protease GlpG.

Wang Y, Ha Y.

Proc Natl Acad Sci U S A. 2007 Feb 13;104(7):2098-102. Epub 2007 Feb 2.

12.
13.

The structural basis for catalysis and substrate specificity of a rhomboid protease.

Vinothkumar KR, Strisovsky K, Andreeva A, Christova Y, Verhelst S, Freeman M.

EMBO J. 2010 Nov 17;29(22):3797-809. doi: 10.1038/emboj.2010.243. Epub 2010 Oct 1.

14.

The role of L1 loop in the mechanism of rhomboid intramembrane protease GlpG.

Wang Y, Maegawa S, Akiyama Y, Ha Y.

J Mol Biol. 2007 Dec 7;374(4):1104-13. Epub 2007 Oct 11.

15.

Activity Assays for Rhomboid Proteases.

Arutyunova E, Strisovsky K, Lemieux MJ.

Methods Enzymol. 2017;584:395-437. doi: 10.1016/bs.mie.2016.11.002. Epub 2016 Dec 8.

PMID:
28065272
16.

Structural basis for intramembrane proteolysis by rhomboid serine proteases.

Ben-Shem A, Fass D, Bibi E.

Proc Natl Acad Sci U S A. 2007 Jan 9;104(2):462-6. Epub 2006 Dec 26.

18.

Proteolytic action of GlpG, a rhomboid protease in the Escherichia coli cytoplasmic membrane.

Maegawa S, Ito K, Akiyama Y.

Biochemistry. 2005 Oct 18;44(41):13543-52.

PMID:
16216077
19.

How does the exosite of rhomboid protease affect substrate processing and inhibition?

Shokhen M, Albeck A.

Protein Sci. 2017 Dec;26(12):2355-2366. doi: 10.1002/pro.3294. Epub 2017 Oct 24.

PMID:
28884847
20.

Conformational change in rhomboid protease GlpG induced by inhibitor binding to its S' subsites.

Xue Y, Chowdhury S, Liu X, Akiyama Y, Ellman J, Ha Y.

Biochemistry. 2012 May 8;51(18):3723-31. doi: 10.1021/bi300368b. Epub 2012 Apr 24.

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