Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 74

1.

5-HT6 receptors and Alzheimer's disease.

Ramírez MJ.

Alzheimers Res Ther. 2013 Apr 22;5(2):15. doi: 10.1186/alzrt169. eCollection 2013. Review.

2.

Serotonin 5-HT6 Receptor Antagonists in Alzheimer's Disease: Therapeutic Rationale and Current Development Status.

Ferrero H, Solas M, Francis PT, Ramirez MJ.

CNS Drugs. 2017 Jan;31(1):19-32. doi: 10.1007/s40263-016-0399-3. Review.

PMID:
27914038
3.

Investigational drugs targeting 5-HT6 receptors for the treatment of Alzheimer's disease.

Wicke K, Haupt A, Bespalov A.

Expert Opin Investig Drugs. 2015;24(12):1515-28. doi: 10.1517/13543784.2015.1102884. Epub 2015 Nov 7. Review.

PMID:
26548316
4.

Antagonism of the 5-HT6 receptor - Preclinical rationale for the treatment of Alzheimer's disease.

de Jong IEM, Mørk A.

Neuropharmacology. 2017 Oct;125:50-63. doi: 10.1016/j.neuropharm.2017.07.010. Epub 2017 Jul 12. Review.

PMID:
28711518
5.

The procognitive effects of 5-HT6 receptor ligands in animal models of schizophrenia.

Nikiforuk A.

Rev Neurosci. 2014;25(3):367-82. doi: 10.1515/revneuro-2014-0005. Review.

PMID:
24501158
6.

The Role of 5 HT6-Receptor Antagonists in Alzheimer's Disease: An Update.

Khoury R, Grysman N, Gold J, Patel K, Grossberg GT.

Expert Opin Investig Drugs. 2018 May 31. doi: 10.1080/13543784.2018.1483334. [Epub ahead of print]

PMID:
29848076
7.

5-HT6 receptor memory and amnesia: behavioral pharmacology--learning and memory processes.

Meneses A, Pérez-García G, Ponce-Lopez T, Castillo C.

Int Rev Neurobiol. 2011;96:27-47. doi: 10.1016/B978-0-12-385902-0.00002-4. Review.

PMID:
21329783
8.

5-HT(6) receptor and cognition.

Codony X, Vela JM, Ramírez MJ.

Curr Opin Pharmacol. 2011 Feb;11(1):94-100. doi: 10.1016/j.coph.2011.01.004. Epub 2011 Feb 15. Review.

PMID:
21330210
9.

Memory formation and memory alterations: 5-HT6 and 5-HT7 receptors, novel alternative.

Meneses A.

Rev Neurosci. 2014;25(3):325-56. doi: 10.1515/revneuro-2014-0001. Review.

PMID:
24698823
10.

5-HT6 receptor antagonists as novel cognitive enhancing agents for Alzheimer's disease.

Upton N, Chuang TT, Hunter AJ, Virley DJ.

Neurotherapeutics. 2008 Jul;5(3):458-69. doi: 10.1016/j.nurt.2008.05.008. Review.

11.

The serotonin 5-HT6 receptor: a viable drug target for treating cognitive deficits in Alzheimer's disease.

Geldenhuys WJ, Van der Schyf CJ.

Expert Rev Neurother. 2009 Jul;9(7):1073-85. doi: 10.1586/ern.09.51. Review.

PMID:
19589055
12.

Selective 5-HT6 receptor ligands: progress in the development of a novel pharmacological approach to the treatment of obesity and related metabolic disorders.

Heal DJ, Smith SL, Fisas A, Codony X, Buschmann H.

Pharmacol Ther. 2008 Feb;117(2):207-31. Epub 2007 Oct 30. Review.

PMID:
18068807
13.

Effects of 5-HT6 antagonists, Ro-4368554 and SB-258585, in tests used for the detection of cognitive enhancement and antipsychotic-like activity.

Gravius A, Laszy J, Pietraszek M, Sághy K, Nagel J, Chambon C, Wegener N, Valastro B, Danysz W, Gyertyán I.

Behav Pharmacol. 2011 Apr;22(2):122-35. doi: 10.1097/FBP.0b013e328343d804.

PMID:
21301322
14.

Serotonin 5-HT6 receptor antagonists for the treatment of cognitive deficiency in Alzheimer's disease.

Benhamú B, Martín-Fontecha M, Vázquez-Villa H, Pardo L, López-Rodríguez ML.

J Med Chem. 2014 Sep 11;57(17):7160-81. doi: 10.1021/jm5003952. Epub 2014 Jun 3. Review.

PMID:
24850589
15.

5-HT6 receptors: a novel target for cognitive enhancement.

Mitchell ES, Neumaier JF.

Pharmacol Ther. 2005 Dec;108(3):320-33. Epub 2005 Jul 7. Review.

PMID:
16005519
16.

Computational approaches to the design of novel 5-HT6 R ligands.

Ivanenkov YA, Majouga AG, Veselov MS, Chufarova NV, Baranovsky SS, Filkov GI.

Rev Neurosci. 2014;25(3):451-67. doi: 10.1515/revneuro-2014-0030. Review.

PMID:
24867282
17.

A new serotonin 5-HT6 receptor antagonist with procognitive activity - Importance of a halogen bond interaction to stabilize the binding.

González-Vera JA, Medina RA, Martín-Fontecha M, Gonzalez A, de la Fuente T, Vázquez-Villa H, García-Cárceles J, Botta J, McCormick PJ, Benhamú B, Pardo L, López-Rodríguez ML.

Sci Rep. 2017 Jan 24;7:41293. doi: 10.1038/srep41293.

18.

5-HT6 receptor agonist EMD386088 impairs behavioral flexibility and working memory.

Amodeo DA, Peterson S, Pahua A, Posadas R, Hernandez A, Hefner E, Qi D, Vega J.

Behav Brain Res. 2018 Sep 3;349:8-15. doi: 10.1016/j.bbr.2018.04.032. Epub 2018 Apr 30.

PMID:
29715539
19.

Signalling pathways associated with 5-HT6 receptors: relevance for cognitive effects.

Marcos B, Cabero M, Solas M, Aisa B, Ramirez MJ.

Int J Neuropsychopharmacol. 2010 Jul;13(6):775-84. doi: 10.1017/S146114570999054X. Epub 2009 Sep 9.

PMID:
19737440
20.

Neuropharmacological profile of novel and selective 5-HT6 receptor agonists: WAY-181187 and WAY-208466.

Schechter LE, Lin Q, Smith DL, Zhang G, Shan Q, Platt B, Brandt MR, Dawson LA, Cole D, Bernotas R, Robichaud A, Rosenzweig-Lipson S, Beyer CE.

Neuropsychopharmacology. 2008 May;33(6):1323-35. Epub 2007 Jul 11.

Supplemental Content

Support Center