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Items: 1 to 20 of 107

1.

Oxidative stress in cardiovascular diseases and obesity: role of p66Shc and protein kinase C.

De Marchi E, Baldassari F, Bononi A, Wieckowski MR, Pinton P.

Oxid Med Cell Longev. 2013;2013:564961. doi: 10.1155/2013/564961. Review.

2.

Oxidative stress stimulates apoptosis and activates NF-kappaB in osteoblastic cells via a PKCbeta/p66shc signaling cascade: counter regulation by estrogens or androgens.

Almeida M, Han L, Ambrogini E, Bartell SM, Manolagas SC.

Mol Endocrinol. 2010 Oct;24(10):2030-7. doi: 10.1210/me.2010-0189.

3.

Apoptosis and oxidative stress-related diseases: the p66Shc connection.

Pellegrini M, Baldari CT.

Curr Mol Med. 2009 Apr;9(3):392-8. Review.

PMID:
19355920
4.

p66Shc-generated oxidative signal promotes fat accumulation.

Berniakovich I, Trinei M, Stendardo M, Migliaccio E, Minucci S, Bernardi P, Pelicci PG, Giorgio M.

J Biol Chem. 2008 Dec 5;283(49):34283-93. doi: 10.1074/jbc.M804362200.

5.

p66 Shc as the engine of vascular aging.

Paneni F, Cosentino F.

Curr Vasc Pharmacol. 2012 Nov;10(6):697-9. Review.

PMID:
23259557
6.

Canonical Wnt signaling induces vascular endothelial dysfunction via p66Shc-regulated reactive oxygen species.

Vikram A, Kim YR, Kumar S, Naqvi A, Hoffman TA, Kumar A, Miller FJ Jr, Kim CS, Irani K.

Arterioscler Thromb Vasc Biol. 2014 Oct;34(10):2301-9. doi: 10.1161/ATVBAHA.114.304338.

7.

The role of p66Shc deletion in age-associated arterial dysfunction and disease states.

Camici GG, Cosentino F, Tanner FC, Lüscher TF.

J Appl Physiol (1985). 2008 Nov;105(5):1628-31. doi: 10.1152/japplphysiol.90579.2008. Review.

8.

p66(Shc) protein, oxidative stress, and cardiovascular complications of diabetes: the missing link.

Francia P, Cosentino F, Schiavoni M, Huang Y, Perna E, Camici GG, Lüscher TF, Volpe M.

J Mol Med (Berl). 2009 Sep;87(9):885-91. doi: 10.1007/s00109-009-0499-3. Review.

PMID:
19590843
9.

[Role of the p66Shc protein in physiological state and in pathologies].

Lebiedzińska M, Suski J, Duszyński J, Wieckowski MR.

Postepy Biochem. 2010;56(2):165-73. Review. Polish.

PMID:
20873111
10.

Final common molecular pathways of aging and cardiovascular disease: role of the p66Shc protein.

Cosentino F, Francia P, Camici GG, Pelicci PG, Lüscher TF, Volpe M.

Arterioscler Thromb Vasc Biol. 2008 Apr;28(4):622-8. Review. Erratum in: Arterioscler Thromb Vasc Biol. 2008 Aug;28(8):e154. Volpe, Massimo [added].

11.

The interplay between p66Shc, reactive oxygen species and cancer cell metabolism.

Lebiedzinska-Arciszewska M, Oparka M, Vega-Naredo I, Karkucinska-Wieckowska A, Pinton P, Duszynski J, Wieckowski MR.

Eur J Clin Invest. 2015 Jan;45 Suppl 1:25-31. doi: 10.1111/eci.12364. Review.

PMID:
25524583
12.

The p66Shc protein controls redox signaling and oxidation-dependent DNA damage in human liver cells.

Perrini S, Tortosa F, Natalicchio A, Pacelli C, Cignarelli A, Palmieri VO, Caccioppoli C, De Stefano F, Porro S, Leonardini A, Ficarella R, De Fazio M, Cocco T, Puglisi F, Laviola L, Palasciano G, Giorgino F.

Am J Physiol Gastrointest Liver Physiol. 2015 Nov 15;309(10):G826-40. doi: 10.1152/ajpgi.00041.2015.

13.

Cardiovascular determinants of life span.

Shi Y, Camici GG, Lüscher TF.

Pflugers Arch. 2010 Jan;459(2):315-24. doi: 10.1007/s00424-009-0727-2. Review.

PMID:
19756718
14.

CRIF1 deficiency induces p66shc-mediated oxidative stress and endothelial activation.

Nagar H, Jung SB, Kwon SK, Park JB, Shong M, Song HJ, Jeon BH, Irani K, Kim CS.

PLoS One. 2014 Jun 6;9(6):e98670. doi: 10.1371/journal.pone.0098670.

15.

Disrupted ATP synthase activity and mitochondrial hyperpolarisation-dependent oxidative stress is associated with p66Shc phosphorylation in fibroblasts of NARP patients.

Lebiedzinska M, Karkucinska-Wieckowska A, Wojtala A, Suski JM, Szabadkai G, Wilczynski G, Wlodarczyk J, Diogo CV, Oliveira PJ, Tauber J, Ježek P, Pronicki M, Duszynski J, Pinton P, Wieckowski MR.

Int J Biochem Cell Biol. 2013 Jan;45(1):141-50. doi: 10.1016/j.biocel.2012.07.020.

PMID:
22885148
16.

Essential role of the redox-sensitive kinase p66shc in determining energetic and oxidative status and cell fate in neuronal preconditioning.

Brown JE, Zeiger SL, Hettinger JC, Brooks JD, Holt B, Morrow JD, Musiek ES, Milne G, McLaughlin B.

J Neurosci. 2010 Apr 14;30(15):5242-52. doi: 10.1523/JNEUROSCI.6366-09.2010.

17.

Chronic nicotine exposure augments renal oxidative stress and injury through transcriptional activation of p66shc.

Arany I, Clark J, Reed DK, Juncos LA.

Nephrol Dial Transplant. 2013 Jun;28(6):1417-25. doi: 10.1093/ndt/gfs596.

18.

[P66shc action on resistance of colon carcinoma RKO cells to oxidative stress].

Galimov ER, Sidorenko AS, Tereshkova AV, Pletiushkina OIu, Cherniak BV, Chumakov PM.

Mol Biol (Mosk). 2012 Jan-Feb;46(1):139-46. Russian.

PMID:
22642111
19.

p66Shc links alpha1-adrenergic receptors to a reactive oxygen species-dependent AKT-FOXO3A phosphorylation pathway in cardiomyocytes.

Guo J, Gertsberg Z, Ozgen N, Steinberg SF.

Circ Res. 2009 Mar 13;104(5):660-9. doi: 10.1161/CIRCRESAHA.108.186288.

20.

p66Shc, a multifaceted protein linking Erk signalling, glucose metabolism, and oxidative stress.

Natalicchio A, Tortosa F, Perrini S, Laviola L, Giorgino F.

Arch Physiol Biochem. 2011 Jul;117(3):116-24. doi: 10.3109/13813455.2011.562513. Review.

PMID:
21506908
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