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Items: 1 to 20 of 91

1.

Sparstolonin B suppresses lipopolysaccharide-induced inflammation in human umbilical vein endothelial cells.

Liang Q, Yu F, Cui X, Duan J, Wu Q, Nagarkatti P, Fan D.

Arch Pharm Res. 2013 Jul;36(7):890-6. doi: 10.1007/s12272-013-0120-8. Epub 2013 Apr 20.

2.

Sparstolonin B inhibits lipopolysaccharide-induced inflammation in 3T3-L1 adipocytes.

Wang M, Xiu L, Diao J, Wei L, Sun J.

Eur J Pharmacol. 2015 Dec 15;769:79-85. doi: 10.1016/j.ejphar.2015.10.050. Epub 2015 Oct 30.

PMID:
26522926
3.

Characterization of sparstolonin B, a Chinese herb-derived compound, as a selective Toll-like receptor antagonist with potent anti-inflammatory properties.

Liang Q, Wu Q, Jiang J, Duan J, Wang C, Smith MD, Lu H, Wang Q, Nagarkatti P, Fan D.

J Biol Chem. 2011 Jul 29;286(30):26470-9. doi: 10.1074/jbc.M111.227934. Epub 2011 Jun 10.

4.

Protective effects of Sparstolonin B, a selective TLR2 and TLR4 antagonist, on mouse endotoxin shock.

Liang Q, Dong S, Lei L, Liu J, Zhang J, Li J, Duan J, Fan D.

Cytokine. 2015 Oct;75(2):302-9. doi: 10.1016/j.cyto.2014.12.003. Epub 2015 Jan 5.

5.

Inhibition of p38 and ERK1/2 pathways by Sparstolonin B suppresses inflammation-induced melanoma metastasis.

Tang YM, Cao QY, Guo XY, Dong SH, Duan JA, Wu QN, Liang QL.

Biomed Pharmacother. 2018 Feb;98:382-389. doi: 10.1016/j.biopha.2017.12.047. Epub 2017 Dec 27.

PMID:
29276966
6.

Sparstolonin B suppresses rat vascular smooth muscle cell proliferation, migration, inflammatory response and lipid accumulation.

Liu Q, Li J, Liang Q, Wang D, Luo Y, Yu F, Janicki JS, Fan D.

Vascul Pharmacol. 2015 Apr-Jun;67-69:59-66. doi: 10.1016/j.vph.2015.03.015. Epub 2015 Apr 11.

7.

Sparstolonin B attenuates hypoxia-reoxygenation-induced cardiomyocyte inflammation.

Liu Q, Wang J, Liang Q, Wang D, Luo Y, Li J, Janicki JS, Fan D.

Exp Biol Med (Maywood). 2014 Mar;239(3):376-84. doi: 10.1177/1535370213517620. Epub 2014 Jan 29.

PMID:
24477822
8.

TAK-242 suppresses lipopolysaccharide-induced inflammation in human coronary artery endothelial cells.

Wei Z, Sun X, Xu Q, Zhang Y, Tian F, Sun H, Zheng H, Dai J.

Pharmazie. 2016 Oct 1;71(10):583-587. doi: 10.1691/ph.2016.6512.

PMID:
29441926
9.

Sparstolonin B attenuates early liver inflammation in experimental NASH by modulating TLR4 trafficking in lipid rafts via NADPH oxidase activation.

Dattaroy D, Seth RK, Das S, Alhasson F, Chandrashekaran V, Michelotti G, Fan D, Nagarkatti M, Nagarkatti P, Diehl AM, Chatterjee S.

Am J Physiol Gastrointest Liver Physiol. 2016 Apr 1;310(7):G510-25. doi: 10.1152/ajpgi.00259.2015. Epub 2015 Dec 30.

10.

Sparstolonin B inhibits pro-angiogenic functions and blocks cell cycle progression in endothelial cells.

Bateman HR, Liang Q, Fan D, Rodriguez V, Lessner SM.

PLoS One. 2013 Aug 5;8(8):e70500. doi: 10.1371/journal.pone.0070500. Print 2013.

11.

The dipeptidyl peptidase-IV inhibitor inhibits the expression of vascular adhesion molecules and inflammatory cytokines in HUVECs via Akt- and AMPK-dependent mechanisms.

Hwang HJ, Chung HS, Jung TW, Ryu JY, Hong HC, Seo JA, Kim SG, Kim NH, Choi KM, Choi DS, Baik SH, Yoo HJ.

Mol Cell Endocrinol. 2015 Apr 15;405:25-34. doi: 10.1016/j.mce.2015.01.025. Epub 2015 Feb 4.

PMID:
25661535
12.

Sparstolonin B attenuates hypoxia-induced apoptosis, necrosis and inflammation in cultured rat left ventricular tissue slices.

Liu Q, Li J, Jubair S, Wang D, Luo Y, Fan D, Janicki JS.

Cardiovasc Drugs Ther. 2014 Oct;28(5):433-9. doi: 10.1007/s10557-014-6545-6.

13.

Angiopoietin-1 inhibits toll-like receptor 4 signalling in cultured endothelial cells: role of miR-146b-5p.

Echavarria R, Mayaki D, Neel JC, Harel S, Sanchez V, Hussain SN.

Cardiovasc Res. 2015 Jun 1;106(3):465-77. doi: 10.1093/cvr/cvv120. Epub 2015 Mar 30.

PMID:
25824148
14.

Lipopolysaccharide and sphingosine-1-phosphate cooperate to induce inflammatory molecules and leukocyte adhesion in endothelial cells.

Fernández-Pisonero I, Dueñas AI, Barreiro O, Montero O, Sánchez-Madrid F, García-Rodríguez C.

J Immunol. 2012 Dec 1;189(11):5402-10. doi: 10.4049/jimmunol.1201309. Epub 2012 Oct 22.

15.

GEF-H1/RhoA signalling pathway mediates lipopolysaccharide-induced intercellular adhesion molecular-1 expression in endothelial cells via activation of p38 and NF-κB.

Guo F, Zhou Z, Dou Y, Tang J, Gao C, Huan J.

Cytokine. 2012 Mar;57(3):417-28. doi: 10.1016/j.cyto.2011.12.009. Epub 2012 Jan 9.

PMID:
22226621
16.

Vascular barrier protective effects of pellitorine in LPS-induced inflammation in vitro and in vivo.

Lee W, Ku SK, Min BW, Lee S, Jee JG, Kim JA, Bae JS.

Fitoterapia. 2014 Jan;92:177-87. doi: 10.1016/j.fitote.2013.11.006. Epub 2013 Nov 18.

PMID:
24262867
17.

Rhein inhibits the expression of vascular cell adhesion molecule 1 in human umbilical vein endothelial cells with or without lipopolysaccharide stimulation.

Hu G, Liu J, Zhen YZ, Wei J, Qiao Y, Lin YJ, Tu P.

Am J Chin Med. 2013;41(3):473-85. doi: 10.1142/S0192415X13500341.

PMID:
23711136
18.
19.

Sparstolonin B, a novel plant derived compound, arrests cell cycle and induces apoptosis in N-myc amplified and N-myc nonamplified neuroblastoma cells.

Kumar A, Fan D, Dipette DJ, Singh US.

PLoS One. 2014 May 1;9(5):e96343. doi: 10.1371/journal.pone.0096343. eCollection 2014. Erratum in: PLoS One. 2016;11(7):e0159082.

20.

The Chinese herb-derived Sparstolonin B suppresses HIV-1 transcription.

Deng X, Zhang Y, Jiang F, Chen R, Peng P, Wen B, Liang J.

Virol J. 2015 Jul 25;12:108. doi: 10.1186/s12985-015-0339-8.

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