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Items: 1 to 20 of 100

1.

2-(2-Methylfuran-3-carboxamido)-3-phenylpropanoic acid, a potential CYP26A1 inhibitor to enhance all-trans retinoic acid-induced leukemia cell differentiation based on virtual screening and biological evaluation.

Li F, Zhao D, Ren J, Hao F, Liu G, Jin S, Jing Y, Cheng M.

Bioorg Med Chem. 2013 Jun 1;21(11):3256-61. doi: 10.1016/j.bmc.2013.03.044. Epub 2013 Apr 3.

PMID:
23601821
2.

Molecular recognition of CYP26A1 binding pockets and structure-activity relationship studies for design of potent and selective retinoic acid metabolism blocking agents.

Sun B, Song S, Hao CZ, Huang WX, Liu CC, Xie HL, Lin B, Cheng MS, Zhao DM.

J Mol Graph Model. 2015 Mar;56:10-9. doi: 10.1016/j.jmgm.2014.11.014. Epub 2014 Dec 8.

PMID:
25541526
3.

Synthesis and biological evaluation of 3-phenyl-3-aryl carboxamido propanoic acid derivatives as small molecule inhibitors of retinoic acid 4-hydroxylase (CYP26A1).

Zhao D, Sun B, Ren J, Li F, Song S, Lv X, Hao C, Cheng M.

Bioorg Med Chem. 2015 Mar 15;23(6):1356-65. doi: 10.1016/j.bmc.2014.11.036. Epub 2015 Jan 21.

PMID:
25684424
6.

Src family kinase inhibitor PP2 enhances differentiation of acute promyelocytic leukemia cell line induced by combination of all-trans-retinoic acid and arsenic trioxide.

Jung YS, Cheong HJ, Kim SJ, Kim KH, Lee N, Park HS, Won JH.

Leuk Res. 2014 Aug;38(8):977-82. doi: 10.1016/j.leukres.2014.05.019. Epub 2014 Jun 4.

PMID:
24953245
7.

Granulocytic differentiation of human NB4 promyelocytic leukemia cells induced by all-trans retinoic acid metabolites.

Idres N, Benoît G, Flexor MA, Lanotte M, Chabot GG.

Cancer Res. 2001 Jan 15;61(2):700-5.

8.

Design, synthesis, and biological evaluation of amide imidazole derivatives as novel metabolic enzyme CYP26A1 inhibitors.

Sun B, Liu K, Han J, Zhao LY, Su X, Lin B, Zhao DM, Cheng MS.

Bioorg Med Chem. 2015 Oct 15;23(20):6763-73. doi: 10.1016/j.bmc.2015.08.019. Epub 2015 Aug 20.

PMID:
26365710
9.

Effect of NADPH-cytochrome P450 reductase on all-trans-retinoic acid efficacy and cytochrome P450 26A1 expression in human myeloid leukaemia HL-60 cells.

Hu L, Lv JF, Zhuo W, Zhang CM, Zhou HH, Fan L.

J Pharm Pharmacol. 2016 Sep;68(9):1193-202. doi: 10.1111/jphp.12591. Epub 2016 Jul 1.

PMID:
27366899
10.
11.

Regulation of CYP26A1 expression by selective RAR and RXR agonists in human NB4 promyelocytic leukemia cells.

Idres N, Marill J, Chabot GG.

Biochem Pharmacol. 2005 Jun 1;69(11):1595-601. Epub 2005 Apr 2.

PMID:
15896339
12.
13.
14.

Neplanocin A, a potent inhibitor of S-adenosylhomocysteine hydrolase, potentiates granulocytic differentiation of acute promyelocytic leukemia cells induced by all-trans retinoic acid.

Niitsu N, Yamamoto-Yamaguchi Y, Kanatani Y, Shuto S, Matsuda A, Umeda M, Honma Y.

Exp Hematol. 1997 Nov;25(12):1296-303.

PMID:
9357974
15.

WEB-2086 and WEB-2170 trigger apoptosis in both ATRA-sensitive and -resistant promyelocytic leukemia cells and greatly enhance ATRA differentiation potential.

Laurenzana A, Cellai C, Vannucchi AM, Pancrazzi A, Romanelli MN, Paoletti F.

Leukemia. 2005 Mar;19(3):390-5.

PMID:
15674364
16.

Matrix and serine protease expression during leukemic cell differentiation induced by aclacinomycin and all-trans-retinoic acid.

Devy L, Hollender P, Munaut C, Colige A, Garnotel R, Foidart JM, Noël A, Jeannesson P.

Biochem Pharmacol. 2002 Jan 15;63(2):179-89.

17.

Andrographolide inhibits growth of acute promyelocytic leukaemia cells by inducing retinoic acid receptor-independent cell differentiation and apoptosis.

Manikam SD, Stanslas J.

J Pharm Pharmacol. 2009 Jan;61(1):69-78. doi: 10.1211/jpp/61.01.0010. Erratum in: J Pharm Pharmacol. 2009 May;61(5):687. Manikam, Shiamala T [corrected to Manikam, Shiamala T].

PMID:
19126299
18.

Common defects of different retinoic acid resistant promyelocytic leukemia cells are persistent telomerase activity and nuclear body disorganization.

Nason-Burchenal K, Maerz W, Albanell J, Allopenna J, Martin P, Moore MA, Dmitrovsky E.

Differentiation. 1997 Aug;61(5):321-31.

PMID:
9342843
20.

Pharmacogenomic analysis of acute promyelocytic leukemia cells highlights CYP26 cytochrome metabolism in differential all-trans retinoic acid sensitivity.

Quere R, Baudet A, Cassinat B, Bertrand G, Marti J, Manchon L, Piquemal D, Chomienne C, Commes T.

Blood. 2007 May 15;109(10):4450-60. Epub 2007 Jan 11.

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