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Items: 1 to 20 of 88

1.

Opioid receptors: toward separation of analgesic from undesirable effects.

Law PY, Reggio PH, Loh HH.

Trends Biochem Sci. 2013 Jun;38(6):275-82. doi: 10.1016/j.tibs.2013.03.003. Epub 2013 Apr 16. Review.

2.

A heterodimer-selective agonist shows in vivo relevance of G protein-coupled receptor dimers.

Waldhoer M, Fong J, Jones RM, Lunzer MM, Sharma SK, Kostenis E, Portoghese PS, Whistler JL.

Proc Natl Acad Sci U S A. 2005 Jun 21;102(25):9050-5. Epub 2005 Jun 2.

3.

Opioids and their receptors: Are we there yet?

Pasternak GW.

Neuropharmacology. 2014 Jan;76 Pt B:198-203. doi: 10.1016/j.neuropharm.2013.03.039. Epub 2013 Apr 26. Review.

4.

[Development of opioid tolerance -- molecular mechanisms and clinical consequences].

Freye E, Latasch L.

Anasthesiol Intensivmed Notfallmed Schmerzther. 2003 Jan;38(1):14-26. Review. German.

PMID:
12522725
5.

Antinociceptive profiles of mu and kappa opioid agonists in a rat tooth pulp stimulation procedure.

Steinfels GF, Cook L.

J Pharmacol Exp Ther. 1986 Jan;236(1):111-7.

PMID:
2867210
6.

Opioids: a review.

Chevlen E.

Curr Pain Headache Rep. 2003 Feb;7(1):15-23. Review.

PMID:
12525266
7.

Truncated G protein-coupled mu opioid receptor MOR-1 splice variants are targets for highly potent opioid analgesics lacking side effects.

Majumdar S, Grinnell S, Le Rouzic V, Burgman M, Polikar L, Ansonoff M, Pintar J, Pan YX, Pasternak GW.

Proc Natl Acad Sci U S A. 2011 Dec 6;108(49):19778-83. doi: 10.1073/pnas.1115231108. Epub 2011 Nov 21.

8.

New vistas in opioid control of pain.

Mizoguchi H, Watanabe C, Sakurada T, Sakurada S.

Curr Opin Pharmacol. 2012 Feb;12(1):87-91. doi: 10.1016/j.coph.2011.10.020. Epub 2011 Nov 19. Review.

PMID:
22104733
9.
10.
11.

Supersensitivity to opioid analgesics following chronic opioid antagonist treatment: relationship to receptor selectivity.

Yoburn BC, Shah S, Chan K, Duttaroy A, Davis T.

Pharmacol Biochem Behav. 1995 Jun-Jul;51(2-3):535-9.

PMID:
7667382
12.

Structural improvement of compounds with analgesic activity: AC-MPF4, a compound with mixed anti-inflammatory and antinociceptive activity via opioid receptor.

Rossato MF, Oliveira SM, Trevisan G, Rotta M, Machado P, Martins MA, Ferreira J.

Pharmacol Biochem Behav. 2015 Feb;129:72-8. doi: 10.1016/j.pbb.2014.12.001. Epub 2014 Dec 13.

PMID:
25511393
13.
14.

A new potent analgesic agent with reduced liability to produce morphine tolerance.

Kiraly K, Caputi FF, Hanuska A, Kató E, Balogh M, Köles L, Palmisano M, Riba P, Hosztafi S, Romualdi P, Candeletti S, Ferdinandy P, Fürst S, Al-Khrasani M.

Brain Res Bull. 2015 Aug;117:32-8. doi: 10.1016/j.brainresbull.2015.07.005. Epub 2015 Jul 30.

PMID:
26235542
15.

Multiple opiate receptors: déjà vu all over again.

Pasternak GW.

Neuropharmacology. 2004;47 Suppl 1:312-23. Review.

PMID:
15464147
16.

Mechanisms of the analgesic actions of opiates and opioids.

Dickenson AH.

Br Med Bull. 1991 Jul;47(3):690-702. Review.

PMID:
1665377
17.

Nausea and vomiting side effects with opioid analgesics during treatment of chronic pain: mechanisms, implications, and management options.

Porreca F, Ossipov MH.

Pain Med. 2009 May-Jun;10(4):654-62. doi: 10.1111/j.1526-4637.2009.00583.x. Epub 2009 Mar 19. Review.

PMID:
19302436
18.

Opioid receptors.

Waldhoer M, Bartlett SE, Whistler JL.

Annu Rev Biochem. 2004;73:953-90. Review.

PMID:
15189164
19.

The other side of the opioid story: modulation of cell growth and survival signaling.

Chen YL, Law PY, Loh HH.

Curr Med Chem. 2008;15(8):772-8. Review.

PMID:
18393846
20.

Activity of the delta-opioid receptor is partially reduced, whereas activity of the kappa-receptor is maintained in mice lacking the mu-receptor.

Matthes HW, Smadja C, Valverde O, Vonesch JL, Foutz AS, Boudinot E, Denavit-Saubié M, Severini C, Negri L, Roques BP, Maldonado R, Kieffer BL.

J Neurosci. 1998 Sep 15;18(18):7285-95.

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