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Globular adiponectin modulates expression of programmed cell death 4 and miR-21 in RAW 264.7 macrophages through the MAPK/NF-κB pathway.

Subedi A, Kim MJ, Nepal S, Lee ES, Kim JA, Sohn DH, Song K, Lee SH, Park WS, Jeong BS, Park PH.

FEBS Lett. 2013 May 21;587(10):1556-61. doi: 10.1016/j.febslet.2013.03.040. Epub 2013 Apr 15.


Autocrine and paracrine modulation of microRNA-155 expression by globular adiponectin in RAW 264.7 macrophages: involvement of MAPK/NF-κB pathway.

Subedi A, Park PH.

Cytokine. 2013 Dec;64(3):638-41. doi: 10.1016/j.cyto.2013.09.011. Epub 2013 Sep 29.


Feedback regulations of miR-21 and MAPKs via Pdcd4 and Spry1 are involved in arsenite-induced cell malignant transformation.

Shen L, Ling M, Li Y, Xu Y, Zhou Y, Ye J, Pang Y, Zhao Y, Jiang R, Zhang J, Liu Q.

PLoS One. 2013;8(3):e57652. doi: 10.1371/journal.pone.0057652. Epub 2013 Mar 1.


MicroRNA-21 regulates the ERK/NF-κB signaling pathway to affect the proliferation, migration, and apoptosis of human melanoma A375 cells by targeting SPRY1, PDCD4, and PTEN.

Mao XH, Chen M, Wang Y, Cui PG, Liu SB, Xu ZY.

Mol Carcinog. 2017 Mar;56(3):886-894. doi: 10.1002/mc.22542. Epub 2016 Sep 22.


MicroRNA-16 suppresses the activation of inflammatory macrophages in atherosclerosis by targeting PDCD4.

Liang X, Xu Z, Yuan M, Zhang Y, Zhao B, Wang J, Zhang A, Li G.

Int J Mol Med. 2016 Apr;37(4):967-75. doi: 10.3892/ijmm.2016.2497. Epub 2016 Feb 22.


MicroRNA-182 promotes cell growth, invasion, and chemoresistance by targeting programmed cell death 4 (PDCD4) in human ovarian carcinomas.

Wang YQ, Guo RD, Guo RM, Sheng W, Yin LR.

J Cell Biochem. 2013 Jul;114(7):1464-73. doi: 10.1002/jcb.24488.


Globular Adiponectin Causes Tolerance to LPS-Induced TNF-α Expression via Autophagy Induction in RAW 264.7 Macrophages: Involvement of SIRT1/FoxO3A Axis.

Pun NT, Subedi A, Kim MJ, Park PH.

PLoS One. 2015 May 11;10(5):e0124636. doi: 10.1371/journal.pone.0124636. eCollection 2015. Erratum in: PLoS One. 2015;10(6):e0130370. PLoS One. 2015 Jun 19: doi: 10.1371/journal.pone.0130370.


A microRNA expression signature of osteoclastogenesis.

Sugatani T, Vacher J, Hruska KA.

Blood. 2011 Mar 31;117(13):3648-57. doi: 10.1182/blood-2010-10-311415. Epub 2011 Jan 27.


Downregulation of Pdcd4 by mir-21 facilitates glioblastoma proliferation in vivo.

Gaur AB, Holbeck SL, Colburn NH, Israel MA.

Neuro Oncol. 2011 Jun;13(6):580-90. doi: 10.1093/neuonc/nor033.


NF-κB mediated miR-21 regulation in cardiomyocytes apoptosis under oxidative stress.

Wei C, Li L, Kim IK, Sun P, Gupta S.

Free Radic Res. 2014 Mar;48(3):282-91. doi: 10.3109/10715762.2013.865839. Epub 2013 Dec 10.


Programmed cell death 4 and microRNA 21 inverse expression is maintained in cells and exosomes from ovarian serous carcinoma effusions.

Cappellesso R, Tinazzi A, Giurici T, Simonato F, Guzzardo V, Ventura L, Crescenzi M, Chiarelli S, Fassina A.

Cancer Cytopathol. 2014 Sep;122(9):685-93. doi: 10.1002/cncy.21442. Epub 2014 May 28.


MicroRNA-21, induced by high glucose, modulates macrophage apoptosis via programmed cell death 4.

Shang YY, Fang NN, Wang F, Wang H, Wang ZH, Tang MX, Peng J, Zhang Y, Zhang W, Zhong M.

Mol Med Rep. 2015 Jul;12(1):463-9. doi: 10.3892/mmr.2015.3398. Epub 2015 Feb 27.


The negative costimulatory molecule PD-1 modulates the balance between immunity and tolerance via miR-21.

Iliopoulos D, Kavousanaki M, Ioannou M, Boumpas D, Verginis P.

Eur J Immunol. 2011 Jun;41(6):1754-63. doi: 10.1002/eji.201040646. Epub 2011 May 10.


Regulation of miRNA-21 by reactive oxygen species-activated ERK/NF-κB in arsenite-induced cell transformation.

Ling M, Li Y, Xu Y, Pang Y, Shen L, Jiang R, Zhao Y, Yang X, Zhang J, Zhou J, Wang X, Liu Q.

Free Radic Biol Med. 2012 May 1;52(9):1508-18. doi: 10.1016/j.freeradbiomed.2012.02.020. Epub 2012 Feb 28.


Mechanisms for the anti-inflammatory effects of adiponectin in macrophages.

Huang H, Park PH, McMullen MR, Nagy LE.

J Gastroenterol Hepatol. 2008 Mar;23 Suppl 1:S50-3. doi: 10.1111/j.1440-1746.2007.05284.x. Review.


miR-21 promotes migration and invasion by the miR-21-PDCD4-AP-1 feedback loop in human hepatocellular carcinoma.

Zhu Q, Wang Z, Hu Y, Li J, Li X, Zhou L, Huang Y.

Oncol Rep. 2012 May;27(5):1660-8. doi: 10.3892/or.2012.1682. Epub 2012 Feb 9.


The microRNA-21-PDCD4 axis prevents type 1 diabetes by blocking pancreatic beta cell death.

Ruan Q, Wang T, Kameswaran V, Wei Q, Johnson DS, Matschinsky F, Shi W, Chen YH.

Proc Natl Acad Sci U S A. 2011 Jul 19;108(29):12030-5. doi: 10.1073/pnas.1101450108. Epub 2011 Jul 5.


Mechanical stretch modulates microRNA 21 expression, participating in proliferation and apoptosis in cultured human aortic smooth muscle cells.

Song Jt, Hu B, Qu Hy, Bi Cl, Huang Xz, Zhang M.

PLoS One. 2012;7(10):e47657. doi: 10.1371/journal.pone.0047657. Epub 2012 Oct 17.


Programmed cell death 4 loss increases tumor cell invasion and is regulated by miR-21 in oral squamous cell carcinoma.

Reis PP, Tomenson M, Cervigne NK, Machado J, Jurisica I, Pintilie M, Sukhai MA, Perez-Ordonez B, Grénman R, Gilbert RW, Gullane PJ, Irish JC, Kamel-Reid S.

Mol Cancer. 2010 Sep 10;9:238. doi: 10.1186/1476-4598-9-238.

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