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Premetastatic soil and prevention of breast cancer brain metastasis.

Liu Y, Kosaka A, Ikeura M, Kohanbash G, Fellows-Mayle W, Snyder LA, Okada H.

Neuro Oncol. 2013 Jul;15(7):891-903. doi: 10.1093/neuonc/not031. Epub 2013 Apr 17.


miR-223 suppresses differentiation of tumor-induced CD11b⁺ Gr1⁺ myeloid-derived suppressor cells from bone marrow cells.

Liu Q, Zhang M, Jiang X, Zhang Z, Dai L, Min S, Wu X, He Q, Liu J, Zhang Y, Zhang Z, Yang R.

Int J Cancer. 2011 Dec 1;129(11):2662-73. doi: 10.1002/ijc.25921. Epub 2011 Mar 25.


SHIP represses lung inflammation and inhibits mammary tumor metastasis in BALB/c mice.

Hamilton MJ, Halvorsen EC, LePard NE, Bosiljcic M, Ho VW, Lam V, Banáth J, Bennewith KL, Krystal G.

Oncotarget. 2016 Jan 26;7(4):3677-91. doi: 10.18632/oncotarget.6611.


Proinflammatory S100 proteins regulate the accumulation of myeloid-derived suppressor cells.

Sinha P, Okoro C, Foell D, Freeze HH, Ostrand-Rosenberg S, Srikrishna G.

J Immunol. 2008 Oct 1;181(7):4666-75.


S100a8/a9 released by CD11b+Gr1+ neutrophils activates cardiac fibroblasts to initiate angiotensin II-Induced cardiac inflammation and injury.

Wu Y, Li Y, Zhang C, A X, Wang Y, Cui W, Li H, Du J.

Hypertension. 2014 Jun;63(6):1241-50. doi: 10.1161/HYPERTENSIONAHA.113.02843. Epub 2014 Apr 7.


[Mesenchymal stem cells promote mouse breast tumor progression by inducing the suppressive function of myeloid-derived CD11b⁺ Gr1⁺ cells].

Hu X, Luo Y, Zhou Y, Zhao D, Wu W, Han Z, Feng X.

Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2014 Aug;30(8):785-8. Chinese.


Expansion of CD11b(+)Ly6G (+)Ly6C (int) cells driven by medroxyprogesterone acetate in mice bearing breast tumors restrains NK cell effector functions.

Spallanzani RG, Dalotto-Moreno T, Raffo Iraolagoitia XL, Ziblat A, Domaica CI, Avila DE, Rossi LE, Fuertes MB, Battistone MA, Rabinovich GA, Salatino M, Zwirner NW.

Cancer Immunol Immunother. 2013 Dec;62(12):1781-95. doi: 10.1007/s00262-013-1483-x. Epub 2013 Oct 11.


S100A8/A9 activate key genes and pathways in colon tumor progression.

Ichikawa M, Williams R, Wang L, Vogl T, Srikrishna G.

Mol Cancer Res. 2011 Feb;9(2):133-48. doi: 10.1158/1541-7786.MCR-10-0394. Epub 2011 Jan 12. Erratum in: Mol Cancer Res. 2011 Sep;9(9):1266.


Inhibition of the Kit ligand/c-Kit axis attenuates metastasis in a mouse model mimicking local breast cancer relapse after radiotherapy.

Kuonen F, Laurent J, Secondini C, Lorusso G, Stehle JC, Rausch T, Faes-Van't Hull E, Bieler G, Alghisi GC, Schwendener R, Andrejevic-Blant S, Mirimanoff RO, Rüegg C.

Clin Cancer Res. 2012 Aug 15;18(16):4365-74. Epub 2012 Jun 18.


Prostaglandin E2 promotes tumor progression by inducing myeloid-derived suppressor cells.

Sinha P, Clements VK, Fulton AM, Ostrand-Rosenberg S.

Cancer Res. 2007 May 1;67(9):4507-13.


Celecoxib suppresses hepatoma stemness and progression by up-regulating PTEN.

Chu TH, Chan HH, Kuo HM, Liu LF, Hu TH, Sun CK, Kung ML, Lin SW, Wang EM, Ma YL, Cheng KH, Lai KH, Wen ZH, Hsu PI, Tai MH.

Oncotarget. 2014 Mar 30;5(6):1475-90.


COX-2 inhibition improves immunotherapy and is associated with decreased numbers of myeloid-derived suppressor cells in mesothelioma. Celecoxib influences MDSC function.

Veltman JD, Lambers ME, van Nimwegen M, Hendriks RW, Hoogsteden HC, Aerts JG, Hegmans JP.

BMC Cancer. 2010 Aug 30;10:464. doi: 10.1186/1471-2407-10-464.


PGE(2)-induced CXCL12 production and CXCR4 expression controls the accumulation of human MDSCs in ovarian cancer environment.

Obermajer N, Muthuswamy R, Odunsi K, Edwards RP, Kalinski P.

Cancer Res. 2011 Dec 15;71(24):7463-70. doi: 10.1158/0008-5472.CAN-11-2449. Epub 2011 Oct 24.


Licochalcone E present in licorice suppresses lung metastasis in the 4T1 mammary orthotopic cancer model.

Kwon SJ, Park SY, Kwon GT, Lee KW, Kang YH, Choi MS, Yun JW, Jeon JH, Jun JG, Park JH.

Cancer Prev Res (Phila). 2013 Jun;6(6):603-13. doi: 10.1158/1940-6207.CAPR-13-0012. Epub 2013 Apr 26.


Potent cell growth inhibitory effects in hepatitis B virus X protein positive hepatocellular carcinoma cells by the selective cyclooxygenase-2 inhibitor celecoxib.

Xie H, Gao L, Chai N, Song J, Wang J, Song Z, Chen C, Pan Y, Zhao L, Sun S, Wu K, Feitelson MA, Liu J, Fan D.

Mol Carcinog. 2009 Jan;48(1):56-65. doi: 10.1002/mc.20455.


Interferon regulatory factor-8 modulates the development of tumour-induced CD11b+Gr-1+ myeloid cells.

Stewart TJ, Greeneltch KM, Reid JE, Liewehr DJ, Steinberg SM, Liu K, Abrams SI.

J Cell Mol Med. 2009 Sep;13(9B):3939-50. doi: 10.1111/j.1582-4934.2009.00685.x.


COX-2 blockade suppresses gliomagenesis by inhibiting myeloid-derived suppressor cells.

Fujita M, Kohanbash G, Fellows-Mayle W, Hamilton RL, Komohara Y, Decker SA, Ohlfest JR, Okada H.

Cancer Res. 2011 Apr 1;71(7):2664-74. doi: 10.1158/0008-5472.CAN-10-3055. Epub 2011 Feb 15.


Tumor microenvironmental conversion of natural killer cells into myeloid-derived suppressor cells.

Park YJ, Song B, Kim YS, Kim EK, Lee JM, Lee GE, Kim JO, Kim YJ, Chang WS, Kang CY.

Cancer Res. 2013 Sep 15;73(18):5669-81. doi: 10.1158/0008-5472.CAN-13-0545. Epub 2013 Jul 18.


Dipyridamole prevents triple-negative breast-cancer progression.

Spano D, Marshall JC, Marino N, De Martino D, Romano A, Scoppettuolo MN, Bello AM, Di Dato V, Navas L, De Vita G, Medaglia C, Steeg PS, Zollo M.

Clin Exp Metastasis. 2013 Jan;30(1):47-68. doi: 10.1007/s10585-012-9506-0. Epub 2012 Jul 4.


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