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Items: 1 to 20 of 100

1.

A dual read-out assay to evaluate the potency of compounds active against Mycobacterium tuberculosis.

Ollinger J, Bailey MA, Moraski GC, Casey A, Florio S, Alling T, Miller MJ, Parish T.

PLoS One. 2013 Apr 4;8(4):e60531. doi: 10.1371/journal.pone.0060531. Print 2013.

2.

Identification of a novel inhibitor of isocitrate lyase as a potent antitubercular agent against both active and non-replicating Mycobacterium tuberculosis.

Liu Y, Zhou S, Deng Q, Li X, Meng J, Guan Y, Li C, Xiao C.

Tuberculosis (Edinb). 2016 Mar;97:38-46. doi: 10.1016/j.tube.2015.12.003. Epub 2016 Jan 6.

PMID:
26980494
3.

The 4-aminopiperidine series has limited anti-tubercular and anti-staphylococcus aureus activity.

Chandrasekera NS, Alling T, Bailey M, Korkegian A, Ahn J, Ovechkina Y, Odingo J, Parish T.

J Negat Results Biomed. 2015 Feb 13;14:4. doi: 10.1186/s12952-015-0024-x.

4.

The use of microarray analysis to determine the gene expression profiles of Mycobacterium tuberculosis in response to anti-bacterial compounds.

Waddell SJ, Stabler RA, Laing K, Kremer L, Reynolds RC, Besra GS.

Tuberculosis (Edinb). 2004;84(3-4):263-74.

PMID:
15207496
5.

Generation of a novel nucleic acid-based reporter system to detect phenotypic susceptibility to antibiotics in Mycobacterium tuberculosis.

Mulvey MC, Sacksteder KA, Einck L, Nacy CA.

MBio. 2012 Mar 13;3(2). pii: e00312-11. doi: 10.1128/mBio.00312-11. Print 2012.

6.

Development of an Intracellular Screen for New Compounds Able To Inhibit Mycobacterium tuberculosis Growth in Human Macrophages.

Sorrentino F, Gonzalez del Rio R, Zheng X, Presa Matilla J, Torres Gomez P, Martinez Hoyos M, Perez Herran ME, Mendoza Losana A, Av-Gay Y.

Antimicrob Agents Chemother. 2015 Oct 26;60(1):640-5. doi: 10.1128/AAC.01920-15.

7.

Anti-tubercular screening of natural products from Colombian plants: 3-methoxynordomesticine, an inhibitor of MurE ligase of Mycobacterium tuberculosis.

Guzman JD, Gupta A, Evangelopoulos D, Basavannacharya C, Pabon LC, Plazas EA, Muñoz DR, Delgado WA, Cuca LE, Ribon W, Gibbons S, Bhakta S.

J Antimicrob Chemother. 2010 Oct;65(10):2101-7. doi: 10.1093/jac/dkq313. Epub 2010 Aug 18.

PMID:
20719764
8.

High-throughput screen identifies small molecule inhibitors targeting acetyltransferase activity of Mycobacterium tuberculosis GlmU.

Rani C, Mehra R, Sharma R, Chib R, Wazir P, Nargotra A, Khan IA.

Tuberculosis (Edinb). 2015 Dec;95(6):664-77. doi: 10.1016/j.tube.2015.06.003. Epub 2015 Jul 31.

PMID:
26318557
9.

Novel amide and sulphonamide derivatives of 6-(piperazin-1-yl)phenanthridine as potent Mycobacterium tuberculosis H37Rv inhibitors.

Naidu KM, Nagesh HN, Singh M, Sriram D, Yogeeswari P, Gowri Chandra Sekhar KV.

Eur J Med Chem. 2015 Mar 6;92:415-26. doi: 10.1016/j.ejmech.2015.01.013. Epub 2015 Jan 9.

PMID:
25590862
10.

Synthesis and structure activity relationship of imidazo[1,2-a]pyridine-8-carboxamides as a novel antimycobacterial lead series.

Ramachandran S, Panda M, Mukherjee K, Choudhury NR, Tantry SJ, Kedari CK, Ramachandran V, Sharma S, Ramya VK, Guptha S, Sambandamurthy VK.

Bioorg Med Chem Lett. 2013 Sep 1;23(17):4996-5001. doi: 10.1016/j.bmcl.2013.06.043. Epub 2013 Jun 24.

PMID:
23867166
11.

Determination of the activity of standard anti-tuberculosis drugs against intramacrophage Mycobacterium tuberculosis, in vitro: MGIT 960 as a viable alternative for BACTEC 460.

Jhamb SS, Goyal A, Singh PP.

Braz J Infect Dis. 2014 May-Jun;18(3):336-40. doi: 10.1016/j.bjid.2013.12.004. Epub 2014 Apr 4.

12.

A New Screen for Tuberculosis Drug Candidates Utilizing a Luciferase-Expressing Recombinant Mycobacterium bovis Bacillus Calmette-Guéren.

Ozeki Y, Igarashi M, Doe M, Tamaru A, Kinoshita N, Ogura Y, Iwamoto T, Sawa R, Umekita M, Enany S, Nishiuchi Y, Osada-Oka M, Hayashi T, Niki M, Tateishi Y, Hatano M, Matsumoto S.

PLoS One. 2015 Nov 16;10(11):e0141658. doi: 10.1371/journal.pone.0141658. eCollection 2015.

13.

Synthesis and biological evaluation of new imidazo[2,1-b][1,3,4]thiadiazole-benzimidazole derivatives.

Ramprasad J, Nayak N, Dalimba U, Yogeeswari P, Sriram D, Peethambar SK, Achur R, Kumar HS.

Eur J Med Chem. 2015 May 5;95:49-63. doi: 10.1016/j.ejmech.2015.03.024. Epub 2015 Mar 14.

PMID:
25794789
15.

Rapid mycobacteria drug susceptibility testing using Gel Microdrop (GMD) Growth Assay and flow cytometry.

Akselband Y, Cabral C, Shapiro DS, McGrath P.

J Microbiol Methods. 2005 Aug;62(2):181-97. Epub 2005 Mar 29.

PMID:
16009276
16.

Detection of anti-tuberculosis activity in some folklore plants by radiometric BACTEC assay.

Gupta VK, Shukla C, Bisht GR, Saikia D, Kumar S, Thakur RL.

Lett Appl Microbiol. 2011 Jan;52(1):33-40. doi: 10.1111/j.1472-765X.2010.02963.x. Epub 2010 Nov 29.

17.

Novel 1,4-substituted-1,2,3-triazoles as antitubercular agents.

Altimari JM, Hockey SC, Boshoff HI, Sajid A, Henderson LC.

ChemMedChem. 2015 May;10(5):787-91. doi: 10.1002/cmdc.201500051. Epub 2015 Mar 18.

PMID:
25788466
18.

Rapid culture-based methods for drug-resistance detection in Mycobacterium tuberculosis.

Palomino JC, Martin A, Von Groll A, Portaels F.

J Microbiol Methods. 2008 Oct;75(2):161-6. doi: 10.1016/j.mimet.2008.06.015. Epub 2008 Jun 25. Review.

PMID:
18627779
19.

An integrated surrogate model for screening of drugs against Mycobacterium tuberculosis.

Gupta A, Bhakta S.

J Antimicrob Chemother. 2012 Jun;67(6):1380-91. doi: 10.1093/jac/dks056. Epub 2012 Mar 7.

PMID:
22398649
20.

3-benzylidene-4-chromanones: a novel cluster of anti-tubercular agents.

Das U, Lorand T, Dimmock SG, Perjesi P, Dimmock JR.

J Enzyme Inhib Med Chem. 2015 Apr;30(2):259-63. doi: 10.3109/14756366.2014.913036. Epub 2014 Jun 18.

PMID:
24939095

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