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Items: 1 to 20 of 114

1.

Ectodysplasin/NF-κB signaling in embryonic mammary gland development.

Lindfors PH, Voutilainen M, Mikkola ML.

J Mammary Gland Biol Neoplasia. 2013 Jun;18(2):165-9. doi: 10.1007/s10911-013-9277-5. Epub 2013 Apr 17. Review.

PMID:
23591968
2.

Ectodysplasin regulates hormone-independent mammary ductal morphogenesis via NF-κB.

Voutilainen M, Lindfors PH, Lefebvre S, Ahtiainen L, Fliniaux I, Rysti E, Murtoniemi M, Schneider P, Schmidt-Ullrich R, Mikkola ML.

Proc Natl Acad Sci U S A. 2012 Apr 10;109(15):5744-9. doi: 10.1073/pnas.1110627109. Epub 2012 Mar 26.

3.

Ectodysplasin and Wnt pathways are required for salivary gland branching morphogenesis.

Häärä O, Fujimori S, Schmidt-Ullrich R, Hartmann C, Thesleff I, Mikkola ML.

Development. 2011 Jul;138(13):2681-91. doi: 10.1242/dev.057711.

4.

Ectodysplasin receptor-mediated signaling is essential for embryonic submandibular salivary gland development.

Jaskoll T, Zhou YM, Trump G, Melnick M.

Anat Rec A Discov Mol Cell Evol Biol. 2003 Apr;271(2):322-31.

5.

Ectodysplasin/NF-κB Promotes Mammary Cell Fate via Wnt/β-catenin Pathway.

Voutilainen M, Lindfors PH, Trela E, Lönnblad D, Shirokova V, Elo T, Rysti E, Schmidt-Ullrich R, Schneider P, Mikkola ML.

PLoS Genet. 2015 Nov 18;11(11):e1005676. doi: 10.1371/journal.pgen.1005676. eCollection 2015 Nov.

6.

The ectodysplasin pathway: from diseases to adaptations.

Sadier A, Viriot L, Pantalacci S, Laudet V.

Trends Genet. 2014 Jan;30(1):24-31. doi: 10.1016/j.tig.2013.08.006. Epub 2013 Sep 23. Review.

PMID:
24070496
7.

Identification of dkk4 as a target of Eda-A1/Edar pathway reveals an unexpected role of ectodysplasin as inhibitor of Wnt signalling in ectodermal placodes.

Fliniaux I, Mikkola ML, Lefebvre S, Thesleff I.

Dev Biol. 2008 Aug 1;320(1):60-71. doi: 10.1016/j.ydbio.2008.04.023. Epub 2008 Apr 26.

8.

Molecular aspects of hypohidrotic ectodermal dysplasia.

Mikkola ML.

Am J Med Genet A. 2009 Sep;149A(9):2031-6. doi: 10.1002/ajmg.a.32855. Review.

PMID:
19681132
9.

Edar and Troy signalling pathways act redundantly to regulate initiation of hair follicle development.

Pispa J, Pummila M, Barker PA, Thesleff I, Mikkola ML.

Hum Mol Genet. 2008 Nov 1;17(21):3380-91. doi: 10.1093/hmg/ddn232. Epub 2008 Aug 9.

PMID:
18689798
10.

Ectodysplasin has a dual role in ectodermal organogenesis: inhibition of Bmp activity and induction of Shh expression.

Pummila M, Fliniaux I, Jaatinen R, James MJ, Laurikkala J, Schneider P, Thesleff I, Mikkola ML.

Development. 2007 Jan;134(1):117-25.

11.

Identification of ectodysplasin target genes reveals the involvement of chemokines in hair development.

Lefebvre S, Fliniaux I, Schneider P, Mikkola ML.

J Invest Dermatol. 2012 Apr;132(4):1094-102. doi: 10.1038/jid.2011.453. Epub 2012 Jan 26.

12.

Salivary gland branching morphogenesis: a quantitative systems analysis of the Eda/Edar/NFkappaB paradigm.

Melnick M, Phair RD, Lapidot SA, Jaskoll T.

BMC Dev Biol. 2009 Jun 6;9:32. doi: 10.1186/1471-213X-9-32.

13.

Reciprocal requirements for EDA/EDAR/NF-kappaB and Wnt/beta-catenin signaling pathways in hair follicle induction.

Zhang Y, Tomann P, Andl T, Gallant NM, Huelsken J, Jerchow B, Birchmeier W, Paus R, Piccolo S, Mikkola ML, Morrisey EE, Overbeek PA, Scheidereit C, Millar SE, Schmidt-Ullrich R.

Dev Cell. 2009 Jul;17(1):49-61. doi: 10.1016/j.devcel.2009.05.011.

14.

Ectodysplasin A (EDA) - EDA receptor signalling and its pharmacological modulation.

Kowalczyk-Quintas C, Schneider P.

Cytokine Growth Factor Rev. 2014 Apr;25(2):195-203. doi: 10.1016/j.cytogfr.2014.01.004. Epub 2014 Jan 23. Review.

PMID:
24508088
15.

NF-kappaB transmits Eda A1/EdaR signalling to activate Shh and cyclin D1 expression, and controls post-initiation hair placode down growth.

Schmidt-Ullrich R, Tobin DJ, Lenhard D, Schneider P, Paus R, Scheidereit C.

Development. 2006 Mar;133(6):1045-57. Epub 2006 Feb 15.

16.

The NF-kappaB signalling pathway in human diseases: from incontinentia pigmenti to ectodermal dysplasias and immune-deficiency syndromes.

Smahi A, Courtois G, Rabia SH, Döffinger R, Bodemer C, Munnich A, Casanova JL, Israël A.

Hum Mol Genet. 2002 Oct 1;11(20):2371-5. Review.

PMID:
12351572
17.

Regulation of hair follicle development by the TNF signal ectodysplasin and its receptor Edar.

Laurikkala J, Pispa J, Jung HS, Nieminen P, Mikkola M, Wang X, Saarialho-Kere U, Galceran J, Grosschedl R, Thesleff I.

Development. 2002 May;129(10):2541-53.

18.

Ectodysplasin signaling in development.

Mikkola ML, Thesleff I.

Cytokine Growth Factor Rev. 2003 Jun-Aug;14(3-4):211-24. Review.

PMID:
12787560
19.

Ectodysplasin signalling deficiency in mouse models of hypohidrotic ectodermal dysplasia leads to middle ear and nasal pathology.

Azar A, Piccinelli C, Brown H, Headon D, Cheeseman M.

Hum Mol Genet. 2016 Aug 15;25(16):3564-3577. doi: 10.1093/hmg/ddw202. Epub 2016 Jul 4.

20.

A rat model of hypohidrotic ectodermal dysplasia carries a missense mutation in the Edaradd gene.

Kuramoto T, Yokoe M, Hashimoto R, Hiai H, Serikawa T.

BMC Genet. 2011 Oct 21;12:91. doi: 10.1186/1471-2156-12-91.

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