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The DecisionDx-UM Gene Expression Profile Test Provides Risk Stratification and Individualized Patient Care in Uveal Melanoma.

Harbour JW, Chen R.

PLoS Curr. 2013 Apr 9;5. pii: ecurrents.eogt.af8ba80fc776c8f1ce8f5dc485d4a618. doi: 10.1371/currents.eogt.af8ba80fc776c8f1ce8f5dc485d4a618.


A prognostic test to predict the risk of metastasis in uveal melanoma based on a 15-gene expression profile.

Harbour JW.

Methods Mol Biol. 2014;1102:427-40. doi: 10.1007/978-1-62703-727-3_22.


Clinical Performance and Management Outcomes with the DecisionDx-UM Gene Expression Profile Test in a Prospective Multicenter Study.

Plasseraud KM, Cook RW, Tsai T, Shildkrot Y, Middlebrook B, Maetzold D, Wilkinson J, Stone J, Johnson C, Oelschlager K, Aaberg TM.

J Oncol. 2016;2016:5325762. doi: 10.1155/2016/5325762. Epub 2016 Jun 30.


Current clinical practice: differential management of uveal melanoma in the era of molecular tumor analyses.

Aaberg TM Jr, Cook RW, Oelschlager K, Maetzold D, Rao PK, Mason JO 3rd.

Clin Ophthalmol. 2014 Dec 3;8:2449-60. doi: 10.2147/OPTH.S70839. eCollection 2014.


Uveal melanoma gene expression profile test result provided for uveal metastasis.

Seider MI, Stewart PJ, Mishra KK, Damato BE.

Ophthalmic Surg Lasers Imaging Retina. 2014 Sep-Oct;45(5):441-2. doi: 10.3928/23258160-20140806-01. Epub 2014 Aug 26.


Variable Results for Uveal Melanoma-Specific Gene Expression Profile Prognostic Test in Choroidal Metastasis.

Klufas MA, Itty S, McCannel CA, Glasgow BJ, Moreno C, McCannel TA.

JAMA Ophthalmol. 2015 Sep;133(9):1073-6. doi: 10.1001/jamaophthalmol.2015.1790.


An accurate, clinically feasible multi-gene expression assay for predicting metastasis in uveal melanoma.

Onken MD, Worley LA, Tuscan MD, Harbour JW.

J Mol Diagn. 2010 Jul;12(4):461-8. doi: 10.2353/jmoldx.2010.090220. Epub 2010 Apr 22.


Collaborative Ocular Oncology Group report number 1: prospective validation of a multi-gene prognostic assay in uveal melanoma.

Onken MD, Worley LA, Char DH, Augsburger JJ, Correa ZM, Nudleman E, Aaberg TM Jr, Altaweel MM, Bardenstein DS, Finger PT, Gallie BL, Harocopos GJ, Hovland PG, McGowan HD, Milman T, Mruthyunjaya P, Simpson ER, Smith ME, Wilson DJ, Wirostko WJ, Harbour JW.

Ophthalmology. 2012 Aug;119(8):1596-603. doi: 10.1016/j.ophtha.2012.02.017. Epub 2012 Apr 21.


Expression of nm23-H1 in uveal melanoma.

Bakalian S, Marshall JC, Faingold D, Logan P, Antecka E, Burnier MN Jr.

Melanoma Res. 2007 Oct;17(5):284-90.


Genomic, prognostic, and cell-signaling advances in uveal melanoma.

Harbour JW.

Am Soc Clin Oncol Educ Book. 2013:388-91. doi: 10.1200/EdBook_AM.2013.33.388. Review.


Independent Prognostic Significance of Gene Expression Profile Class and Largest Basal Diameter of Posterior Uveal Melanomas.

Corrêa ZM, Augsburger JJ.

Am J Ophthalmol. 2016 Feb;162:20-27.e1. doi: 10.1016/j.ajo.2015.11.019. Epub 2015 Nov 18.


MicroRNA expression analysis and Multiplex ligation-dependent probe amplification in metastatic and non-metastatic uveal melanoma.

Larsen AC, Holst L, Kaczkowski B, Andersen MT, Manfé V, Siersma VD, Kolko M, Kiilgaard JF, Winther O, Prause JU, Gniadecki R, Heegaard S.

Acta Ophthalmol. 2014 Sep;92(6):541-9. doi: 10.1111/aos.12322. Epub 2013 Dec 24.


International Validation of the American Joint Committee on Cancer's 7th Edition Classification of Uveal Melanoma.

AJCC Ophthalmic Oncology Task Force.

JAMA Ophthalmol. 2015 Apr;133(4):376-83. doi: 10.1001/jamaophthalmol.2014.5395. Erratum in: JAMA Ophthalmol. 2015 Apr;133(4):493. JAMA Ophthalmol. 2015 Sep;133(9):1096.


Heterogeneity revealed by integrated genomic analysis uncovers a molecular switch in malignant uveal melanoma.

de Lange MJ, van Pelt SI, Versluis M, Jordanova ES, Kroes WG, Ruivenkamp C, van der Burg SH, Luyten GP, van Hall T, Jager MJ, van der Velden PA.

Oncotarget. 2015 Nov 10;6(35):37824-35. doi: 10.18632/oncotarget.5637.


Prognostic value of legumain in uveal melanoma.

Wu T, Sun L, Wu Y, Xiang R, Li Y, Rong W, Sun F, Wang N.

Mol Med Rep. 2016 Mar;13(3):2377-84. doi: 10.3892/mmr.2016.4838. Epub 2016 Jan 29.


EFS shows biallelic methylation in uveal melanoma with poor prognosis as well as tissue-specific methylation.

Neumann LC, Weinhäusel A, Thomas S, Horsthemke B, Lohmann DR, Zeschnigk M.

BMC Cancer. 2011 Aug 26;11:380. doi: 10.1186/1471-2407-11-380.


A review of advanced genetic testing for clinical prognostication in uveal melanoma.

Werdich XQ, Jakobiec FA, Singh AD, Kim IK.

Semin Ophthalmol. 2013 Sep-Nov;28(5-6):361-71. doi: 10.3109/08820538.2013.825290. Epub 2013 Sep 6. Review.


Uveal melanoma: A pathologist's perspective and review of translational developments.

Schoenfield L.

Adv Anat Pathol. 2014 Mar;21(2):138-43. doi: 10.1097/PAP.0000000000000010. Review.


Prognostic testing in uveal melanoma by transcriptomic profiling of fine needle biopsy specimens.

Onken MD, Worley LA, Dávila RM, Char DH, Harbour JW.

J Mol Diagn. 2006 Nov;8(5):567-73.


Micro-RNAs associated with metastasis in uveal melanoma identified by multiplexed microarray profiling.

Worley LA, Long MD, Onken MD, Harbour JW.

Melanoma Res. 2008 Jun;18(3):184-90. doi: 10.1097/CMR.0b013e3282feeac6.


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