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Items: 1 to 20 of 161


Protein-DNA complexes are the primary sources of replication fork pausing in Escherichia coli.

Gupta MK, Guy CP, Yeeles JT, Atkinson J, Bell H, Lloyd RG, Marians KJ, McGlynn P.

Proc Natl Acad Sci U S A. 2013 Apr 30;110(18):7252-7. doi: 10.1073/pnas.1303890110. Epub 2013 Apr 15.


Localization of an accessory helicase at the replisome is critical in sustaining efficient genome duplication.

Atkinson J, Gupta MK, Rudolph CJ, Bell H, Lloyd RG, McGlynn P.

Nucleic Acids Res. 2011 Feb;39(3):949-57. doi: 10.1093/nar/gkq889. Epub 2010 Oct 4.


Rep provides a second motor at the replisome to promote duplication of protein-bound DNA.

Guy CP, Atkinson J, Gupta MK, Mahdi AA, Gwynn EJ, Rudolph CJ, Moon PB, van Knippenberg IC, Cadman CJ, Dillingham MS, Lloyd RG, McGlynn P.

Mol Cell. 2009 Nov 25;36(4):654-66. doi: 10.1016/j.molcel.2009.11.009.


A hand-off mechanism for primosome assembly in replication restart.

Lopper M, Boonsombat R, Sandler SJ, Keck JL.

Mol Cell. 2007 Jun 22;26(6):781-93.


Replication forks blocked by protein-DNA complexes have limited stability in vitro.

McGlynn P, Guy CP.

J Mol Biol. 2008 Aug 29;381(2):249-55. doi: 10.1016/j.jmb.2008.05.053. Epub 2008 May 29.


RecA-promoted, RecFOR-independent progressive disassembly of replisomes stalled by helicase inactivation.

Lia G, Rigato A, Long E, Chagneau C, Le Masson M, Allemand JF, Michel B.

Mol Cell. 2013 Feb 7;49(3):547-57. doi: 10.1016/j.molcel.2012.11.018. Epub 2012 Dec 20. Retraction in: Mol Cell. 2014 May 8;54(3):537.


Stoichiometry and architecture of active DNA replication machinery in Escherichia coli.

Reyes-Lamothe R, Sherratt DJ, Leake MC.

Science. 2010 Apr 23;328(5977):498-501. doi: 10.1126/science.1185757.


The Escherichia coli Tus-Ter replication fork barrier causes site-specific DNA replication perturbation in yeast.

Larsen NB, Sass E, Suski C, Mankouri HW, Hickson ID.

Nat Commun. 2014 Apr 7;5:3574. doi: 10.1038/ncomms4574.


Pfh1 Is an Accessory Replicative Helicase that Interacts with the Replisome to Facilitate Fork Progression and Preserve Genome Integrity.

McDonald KR, Guise AJ, Pourbozorgi-Langroudi P, Cristea IM, Zakian VA, Capra JA, Sabouri N.

PLoS Genet. 2016 Sep 9;12(9):e1006238. doi: 10.1371/journal.pgen.1006238. eCollection 2016 Sep.


PriC-mediated DNA replication restart requires PriC complex formation with the single-stranded DNA-binding protein.

Wessel SR, Marceau AH, Massoni SC, Zhou R, Ha T, Sandler SJ, Keck JL.

J Biol Chem. 2013 Jun 14;288(24):17569-78. doi: 10.1074/jbc.M113.478156. Epub 2013 Apr 29.


Molecular anatomy and regulation of a stable replisome at a paused eukaryotic DNA replication fork.

Calzada A, Hodgson B, Kanemaki M, Bueno A, Labib K.

Genes Dev. 2005 Aug 15;19(16):1905-19.


The Escherichia coli replisome is inherently DNA damage tolerant.

Yeeles JT, Marians KJ.

Science. 2011 Oct 14;334(6053):235-8. doi: 10.1126/science.1209111.


What happens when replication and transcription complexes collide?

Pomerantz RT, O'Donnell M.

Cell Cycle. 2010 Jul 1;9(13):2537-43. doi: 10.4161/cc.9.13.12122. Review.


Direct restart of a replication fork stalled by a head-on RNA polymerase.

Pomerantz RT, O'Donnell M.

Science. 2010 Jan 29;327(5965):590-2. doi: 10.1126/science.1179595.


A Ctf4 trimer couples the CMG helicase to DNA polymerase α in the eukaryotic replisome.

Simon AC, Zhou JC, Perera RL, van Deursen F, Evrin C, Ivanova ME, Kilkenny ML, Renault L, Kjaer S, Matak-Vinković D, Labib K, Costa A, Pellegrini L.

Nature. 2014 Jun 12;510(7504):293-297. doi: 10.1038/nature13234. Epub 2014 May 4.


Whither the replisome: emerging perspectives on the dynamic nature of the DNA replication machinery.

Langston LD, Indiani C, O'Donnell M.

Cell Cycle. 2009 Sep 1;8(17):2686-91. Epub 2009 Sep 29. Review.


A fork-clearing role for UvrD.

Florés MJ, Sanchez N, Michel B.

Mol Microbiol. 2005 Sep;57(6):1664-75.


Accessory replicative helicases and the replication of protein-bound DNA.

Brüning JG, Howard JL, McGlynn P.

J Mol Biol. 2014 Dec 12;426(24):3917-28. doi: 10.1016/j.jmb.2014.10.001. Epub 2014 Oct 13. Review.


Replisome speed determines the efficiency of the Tus-Ter replication termination barrier.

Elshenawy MM, Jergic S, Xu ZQ, Sobhy MA, Takahashi M, Oakley AJ, Dixon NE, Hamdan SM.

Nature. 2015 Sep 17;525(7569):394-8. doi: 10.1038/nature14866. Epub 2015 Aug 31.


Replication fork blockage by transcription factor-DNA complexes in Escherichia coli.

Payne BT, van Knippenberg IC, Bell H, Filipe SR, Sherratt DJ, McGlynn P.

Nucleic Acids Res. 2006;34(18):5194-202. Epub 2006 Sep 25.

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