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Items: 1 to 20 of 99

1.

Notch increases the shedding of HB-EGF by ADAM12 to potentiate invadopodia formation in hypoxia.

Díaz B, Yuen A, Iizuka S, Higashiyama S, Courtneidge SA.

J Cell Biol. 2013 Apr 15;201(2):279-92. doi: 10.1083/jcb.201209151.

2.

Mitogen-activated protein kinase (MAPK) regulates leukotriene D4-induced HB-EGF and ADAM12 expression in human airway smooth muscle cells.

Kumasawa F, Hashimoto S, Mizumura K, Takeshita I, Onose A, Jibiki I, Maruoka S, Gon Y, Kobayashi T, Takahashi N.

Asian Pac J Allergy Immunol. 2013 Mar;31(1):58-66.

3.

Suppression of proHB-EGF carboxy-terminal fragment nuclear translocation: a new molecular target therapy for gastric cancer.

Shimura T, Kataoka H, Ogasawara N, Kubota E, Sasaki M, Tanida S, Joh T.

Clin Cancer Res. 2008 Jun 15;14(12):3956-65. doi: 10.1158/1078-0432.CCR-07-4794.

4.

PACSIN3 binds ADAM12/meltrin alpha and up-regulates ectodomain shedding of heparin-binding epidermal growth factor-like growth factor.

Mori S, Tanaka M, Nanba D, Nishiwaki E, Ishiguro H, Higashiyama S, Matsuura N.

J Biol Chem. 2003 Nov 14;278(46):46029-34.

5.

Targeting autocrine HB-EGF signaling with specific ADAM12 inhibition using recombinant ADAM12 prodomain.

Miller MA, Moss ML, Powell G, Petrovich R, Edwards L, Meyer AS, Griffith LG, Lauffenburger DA.

Sci Rep. 2015 Oct 19;5:15150. doi: 10.1038/srep15150.

6.

Heparin-binding epidermal growth factor-like growth factor promotes transcoelomic metastasis in ovarian cancer through epithelial-mesenchymal transition.

Yagi H, Yotsumoto F, Miyamoto S.

Mol Cancer Ther. 2008 Oct;7(10):3441-51. doi: 10.1158/1535-7163.MCT-08-0417.

7.

The metalloproteinase ADAM-12 regulates bronchial epithelial cell proliferation and apoptosis.

Rocks N, Estrella C, Paulissen G, Quesada-Calvo F, Gilles C, Guéders MM, Crahay C, Foidart JM, Gosset P, Noel A, Cataldo DD.

Cell Prolif. 2008 Dec;41(6):988-1001. doi: 10.1111/j.1365-2184.2008.00557.x.

PMID:
19040574
8.

PKCα and PKCδ regulate ADAM17-mediated ectodomain shedding of heparin binding-EGF through separate pathways.

Kveiborg M, Instrell R, Rowlands C, Howell M, Parker PJ.

PLoS One. 2011 Feb 28;6(2):e17168. doi: 10.1371/journal.pone.0017168.

9.

ADAM-mediated ectodomain shedding of HB-EGF in receptor cross-talk.

Higashiyama S, Nanba D.

Biochim Biophys Acta. 2005 Aug 1;1751(1):110-7. Review.

PMID:
16054021
10.

Lung cancer-derived galectin-1 enhances tumorigenic potentiation of tumor-associated dendritic cells by expressing heparin-binding EGF-like growth factor.

Kuo PL, Huang MS, Cheng DE, Hung JY, Yang CJ, Chou SH.

J Biol Chem. 2012 Mar 23;287(13):9753-64. doi: 10.1074/jbc.M111.321190.

11.

TGFβ induces proHB-EGF shedding and EGFR transactivation through ADAM activation in gastric cancer cells.

Ebi M, Kataoka H, Shimura T, Kubota E, Hirata Y, Mizushima T, Mizoshita T, Tanaka M, Mabuchi M, Tsukamoto H, Tanida S, Kamiya T, Higashiyama S, Joh T.

Biochem Biophys Res Commun. 2010 Nov 19;402(3):449-54. doi: 10.1016/j.bbrc.2010.09.130.

PMID:
20934403
12.

[Membrane-anchored heparin-binding EGF-like growth factor processing by ADAM12 in cardiac hypertrophy].

Higashiyama S.

Nihon Rinsho. 2003 May;61(5):767-75. Review. Japanese.

PMID:
12755001
13.

ADAM12 induces estrogen-independence in breast cancer cells.

Roy R, Moses MA.

Breast Cancer Res Treat. 2012 Feb;131(3):731-41. doi: 10.1007/s10549-011-1431-4.

14.

Proteolytic processing of delta-like 1 by ADAM proteases.

Dyczynska E, Sun D, Yi H, Sehara-Fujisawa A, Blobel CP, Zolkiewska A.

J Biol Chem. 2007 Jan 5;282(1):436-44.

15.

Cardiac hypertrophy is inhibited by antagonism of ADAM12 processing of HB-EGF: metalloproteinase inhibitors as a new therapy.

Asakura M, Kitakaze M, Takashima S, Liao Y, Ishikura F, Yoshinaka T, Ohmoto H, Node K, Yoshino K, Ishiguro H, Asanuma H, Sanada S, Matsumura Y, Takeda H, Beppu S, Tada M, Hori M, Higashiyama S.

Nat Med. 2002 Jan;8(1):35-40.

PMID:
11786904
16.

Wound-induced ATP release and EGF receptor activation in epithelial cells.

Yin J, Xu K, Zhang J, Kumar A, Yu FS.

J Cell Sci. 2007 Mar 1;120(Pt 5):815-25.

17.

Insulin-induced epidermal growth factor activation in vascular smooth muscle cells is ADAM-dependent.

Roztocil E, Nicholl SM, Davies MG.

Surgery. 2008 Aug;144(2):245-51. doi: 10.1016/j.surg.2008.03.023.

18.

Heparin-binding epidermal growth factor-like growth factor is a potent regulator of invasion activity in oral squamous cell carcinoma.

Ohnishi Y, Inoue H, Furukawa M, Kakudo K, Nozaki M.

Oncol Rep. 2012 Apr;27(4):954-8. doi: 10.3892/or.2011.1616.

19.

Clinical significance of heparin-binding epidermal growth factor-like growth factor and a disintegrin and metalloprotease 17 expression in human ovarian cancer.

Tanaka Y, Miyamoto S, Suzuki SO, Oki E, Yagi H, Sonoda K, Yamazaki A, Mizushima H, Maehara Y, Mekada E, Nakano H.

Clin Cancer Res. 2005 Jul 1;11(13):4783-92.

20.

EGF promotes the shedding of soluble E-cadherin in an ADAM10-dependent manner in prostate epithelial cells.

Grabowska MM, Sandhu B, Day ML.

Cell Signal. 2012 Feb;24(2):532-8. doi: 10.1016/j.cellsig.2011.10.004.

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