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Items: 1 to 20 of 107

1.

Reduced LIMK2 expression in colorectal cancer reflects its role in limiting stem cell proliferation.

Lourenço FC, Munro J, Brown J, Cordero J, Stefanatos R, Strathdee K, Orange C, Feller SM, Sansom OJ, Vidal M, Murray GI, Olson MF.

Gut. 2014 Mar;63(3):480-93. doi: 10.1136/gutjnl-2012-303883. Epub 2013 Apr 12.

2.

Prostaglandin E2 Promotes Colorectal Cancer Stem Cell Expansion and Metastasis in Mice.

Wang D, Fu L, Sun H, Guo L, DuBois RN.

Gastroenterology. 2015 Dec;149(7):1884-1895.e4. doi: 10.1053/j.gastro.2015.07.064. Epub 2015 Aug 7.

3.

The role of lysyl oxidase in SRC-dependent proliferation and metastasis of colorectal cancer.

Baker AM, Cox TR, Bird D, Lang G, Murray GI, Sun XF, Southall SM, Wilson JR, Erler JT.

J Natl Cancer Inst. 2011 Mar 2;103(5):407-24. doi: 10.1093/jnci/djq569. Epub 2011 Jan 31.

PMID:
21282564
4.

OVOL2, an Inhibitor of WNT Signaling, Reduces Invasive Activities of Human and Mouse Cancer Cells and Is Down-regulated in Human Colorectal Tumors.

Ye GD, Sun GB, Jiao P, Chen C, Liu QF, Huang XL, Zhang R, Cai WY, Li SN, Wu JF, Liu YJ, Wu RS, Xie YY, Chan EC, Liou YC, Li BA.

Gastroenterology. 2016 Mar;150(3):659-671.e16. doi: 10.1053/j.gastro.2015.11.041. Epub 2015 Nov 24.

PMID:
26619963
5.

Leptin acts as a growth factor for colorectal tumours at stages subsequent to tumour initiation in murine colon carcinogenesis.

Endo H, Hosono K, Uchiyama T, Sakai E, Sugiyama M, Takahashi H, Nakajima N, Wada K, Takeda K, Nakagama H, Nakajima A.

Gut. 2011 Oct;60(10):1363-71. doi: 10.1136/gut.2010.235754. Epub 2011 Mar 15.

PMID:
21406387
6.

Reduced expression of Hugl-1, the human homologue of Drosophila tumour suppressor gene lgl, contributes to progression of colorectal cancer.

Schimanski CC, Schmitz G, Kashyap A, Bosserhoff AK, Bataille F, Schäfer SC, Lehr HA, Berger MR, Galle PR, Strand S, Strand D.

Oncogene. 2005 Apr 28;24(19):3100-9.

PMID:
15735678
7.

High nitric oxide production, secondary to inducible nitric oxide synthase expression, is essential for regulation of the tumour-initiating properties of colon cancer stem cells.

Puglisi MA, Cenciarelli C, Tesori V, Cappellari M, Martini M, Di Francesco AM, Giorda E, Carsetti R, Ricci-Vitiani L, Gasbarrini A.

J Pathol. 2015 Aug;236(4):479-90. doi: 10.1002/path.4545. Epub 2015 May 12.

PMID:
25875314
8.

Elevated OCT1 participates in colon tumorigenesis and independently predicts poor prognoses of colorectal cancer patients.

Wang YP, Song GH, Chen J, Xiao C, Li C, Zhong L, Sun X, Wang ZW, Deng GL, Yu FD, Xue YM, Tang HM, Peng ZH, Wang XL.

Tumour Biol. 2016 Mar;37(3):3247-55. doi: 10.1007/s13277-015-4080-0. Epub 2015 Oct 4.

9.

LIMK1 and LIMK2 are important for metastatic behavior and tumor cell-induced angiogenesis of pancreatic cancer cells.

Vlecken DH, Bagowski CP.

Zebrafish. 2009 Dec;6(4):433-9. doi: 10.1089/zeb.2009.0602.

PMID:
20047470
10.

Presence of Twist1-positive neoplastic cells in the stroma of chromosome-unstable colorectal tumors.

Celesti G, Di Caro G, Bianchi P, Grizzi F, Basso G, Marchesi F, Doni A, Marra G, Roncalli M, Mantovani A, Malesci A, Laghi L.

Gastroenterology. 2013 Sep;145(3):647-57.e15. doi: 10.1053/j.gastro.2013.05.011. Epub 2013 May 15.

PMID:
23684708
11.

PHLPP is a negative regulator of RAF1, which reduces colorectal cancer cell motility and prevents tumor progression in mice.

Li X, Stevens PD, Liu J, Yang H, Wang W, Wang C, Zeng Z, Schmidt MD, Yang M, Lee EY, Gao T.

Gastroenterology. 2014 May;146(5):1301-12.e1-10. doi: 10.1053/j.gastro.2014.02.003. Epub 2014 Feb 11.

12.

β-catenin represses expression of the tumour suppressor 15-prostaglandin dehydrogenase in the normal intestinal epithelium and colorectal tumour cells.

Smartt HJ, Greenhough A, Ordóñez-Morán P, Talero E, Cherry CA, Wallam CA, Parry L, Al Kharusi M, Roberts HR, Mariadason JM, Clarke AR, Huelsken J, Williams AC, Paraskeva C.

Gut. 2012 Sep;61(9):1306-14. doi: 10.1136/gutjnl-2011-300817. Epub 2011 Nov 14.

PMID:
22082586
13.

DDX3 as a strongest prognosis marker and its downregulation promotes metastasis in colorectal cancer.

Su CY, Lin TC, Lin YF, Chen MH, Lee CH, Wang HY, Lee YC, Liu YP, Chen CL, Hsiao M.

Oncotarget. 2015 Jul 30;6(21):18602-12.

14.

Alcohol dehydrogenase, iron containing, 1 promoter hypermethylation associated with colorectal cancer differentiation.

Tae CH, Ryu KJ, Kim SH, Kim HC, Chun HK, Min BH, Chang DK, Rhee PL, Kim JJ, Rhee JC, Kim YH.

BMC Cancer. 2013 Mar 22;13:142. doi: 10.1186/1471-2407-13-142.

15.

MicroRNA-200c modulates epithelial-to-mesenchymal transition (EMT) in human colorectal cancer metastasis.

Hur K, Toiyama Y, Takahashi M, Balaguer F, Nagasaka T, Koike J, Hemmi H, Koi M, Boland CR, Goel A.

Gut. 2013 Sep;62(9):1315-26. doi: 10.1136/gutjnl-2011-301846. Epub 2012 Jun 26.

16.

Troy, a tumor necrosis factor receptor family member, interacts with lgr5 to inhibit wnt signaling in intestinal stem cells.

Fafilek B, Krausova M, Vojtechova M, Pospichalova V, Tumova L, Sloncova E, Huranova M, Stancikova J, Hlavata A, Svec J, Sedlacek R, Luksan O, Oliverius M, Voska L, Jirsa M, Paces J, Kolar M, Krivjanska M, Klimesova K, Tlaskalova-Hogenova H, Korinek V.

Gastroenterology. 2013 Feb;144(2):381-91. doi: 10.1053/j.gastro.2012.10.048. Epub 2012 Nov 7.

PMID:
23142137
17.

Increased expression of Solute carrier family 12 member 5 via gene amplification contributes to tumour progression and metastasis and associates with poor survival in colorectal cancer.

Xu L, Li X, Cai M, Chen J, Li X, Wu WK, Kang W, Tong J, To KF, Guan XY, Sung JJ, Chan FK, Yu J.

Gut. 2016 Apr;65(4):635-46. doi: 10.1136/gutjnl-2014-308257. Epub 2015 May 6.

18.

Potential role of TRIM3 as a novel tumour suppressor in colorectal cancer (CRC) development.

Piao MY, Cao HL, He NN, Xu MQ, Dong WX, Wang WQ, Wang BM, Zhou B.

Scand J Gastroenterol. 2016;51(5):572-82. doi: 10.3109/00365521.2015.1124285. Epub 2015 Dec 22.

PMID:
26691157
19.

ITF2 prevents activation of the β-catenin-TCF4 complex in colon cancer cells and levels decrease with tumor progression.

Shin HW, Choi H, So D, Kim YI, Cho K, Chung HJ, Lee KH, Chun YS, Cho CH, Kang GH, Kim WH, Park JW.

Gastroenterology. 2014 Aug;147(2):430-442.e8. doi: 10.1053/j.gastro.2014.04.047. Epub 2014 May 15.

PMID:
24846398
20.

MicroRNA target for MACC1 and CYR61 to inhibit tumor growth in mice with colorectal cancer.

Wang G, Gu J, Gao Y.

Tumour Biol. 2016 Oct;37(10):13983-13993. Epub 2016 Aug 4.

PMID:
27492459

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