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Items: 1 to 20 of 156

1.

Pleiotropic effect of histamine H4 receptor modulation in the central nervous system.

Galeotti N, Sanna MD, Ghelardini C.

Neuropharmacology. 2013 Aug;71:141-7. doi: 10.1016/j.neuropharm.2013.03.026. Epub 2013 Apr 11.

PMID:
23583928
2.

Histamine H4 receptor activation alleviates neuropathic pain through differential regulation of ERK, JNK, and P38 MAPK phosphorylation.

Sanna MD, Stark H, Lucarini L, Ghelardini C, Masini E, Galeotti N.

Pain. 2015 Dec;156(12):2492-504. doi: 10.1097/j.pain.0000000000000319.

PMID:
26270581
3.

Histamine H4 receptor stimulation suppresses IL-12p70 production and mediates chemotaxis in human monocyte-derived dendritic cells.

Gutzmer R, Diestel C, Mommert S, Köther B, Stark H, Wittmann M, Werfel T.

J Immunol. 2005 May 1;174(9):5224-32.

4.

Pharmacological characterization of the new histamine H4 receptor agonist VUF 8430.

Lim HD, Adami M, Guaita E, Werfel T, Smits RA, de Esch IJ, Bakker RA, Gutzmer R, Coruzzi G, Leurs R.

Br J Pharmacol. 2009 May;157(1):34-43. doi: 10.1111/j.1476-5381.2009.00200.x.

5.

Histamine H4 receptor antagonism diminishes existing airway inflammation and dysfunction via modulation of Th2 cytokines.

Cowden JM, Riley JP, Ma JY, Thurmond RL, Dunford PJ.

Respir Res. 2010 Jun 24;11:86. doi: 10.1186/1465-9921-11-86.

6.

Behavioural phenotype of histamine H4 receptor knockout mice: Focus on central neuronal functions.

Sanna MD, Ghelardini C, Thurmond RL, Masini E, Galeotti N.

Neuropharmacology. 2017 Mar 1;114:48-57. doi: 10.1016/j.neuropharm.2016.11.023. Epub 2016 Nov 27.

PMID:
27899280
7.

Histamine H4 receptor agonists have more activities than H4 agonism in antigen-specific human T-cell responses.

Sugata Y, Okano M, Fujiwara T, Matsumoto R, Hattori H, Yamamoto M, Nishibori M, Nishizaki K.

Immunology. 2007 Jun;121(2):266-75. Epub 2007 Mar 7.

8.

Antinociceptive effects of central administration of the endogenous cannabinoid receptor type 1 agonist VDPVNFKLLSH-OH [(m)VD-hemopressin(α)], an N-terminally extended hemopressin peptide.

Han ZL, Fang Q, Wang ZL, Li XH, Li N, Chang XM, Pan JX, Tang HZ, Wang R.

J Pharmacol Exp Ther. 2014 Feb;348(2):316-23. doi: 10.1124/jpet.113.209866. Epub 2013 Dec 4.

9.

Role of H4 receptor in histamine-mediated responses in human melanoma.

Massari NA, Medina VA, Martinel Lamas DJ, Cricco GP, Croci M, Sambuco L, Bergoc RM, Rivera ES.

Melanoma Res. 2011 Oct;21(5):395-404. doi: 10.1097/CMR.0b013e328347ee53.

PMID:
21691231
10.

Histamine H4 receptors modulate dendritic cell migration through skin--immunomodulatory role of histamine.

Bäumer W, Wendorff S, Gutzmer R, Werfel T, Dijkstra D, Chazot P, Stark H, Kietzmann M.

Allergy. 2008 Oct;63(10):1387-94. doi: 10.1111/j.1398-9995.2008.01720.x.

11.

Role of histamine receptors in the effects of histamine on the production of reactive oxygen species by whole blood phagocytes.

Vasicek O, Lojek A, Jancinova V, Nosal R, Ciz M.

Life Sci. 2014 Mar 28;100(1):67-72. doi: 10.1016/j.lfs.2014.01.082. Epub 2014 Feb 12.

PMID:
24530738
12.

Discovery of S-(2-guanidylethyl)-isothiourea (VUF 8430) as a potent nonimidazole histamine H4 receptor agonist.

Lim HD, Smits RA, Bakker RA, van Dam CM, de Esch IJ, Leurs R.

J Med Chem. 2006 Nov 16;49(23):6650-1.

PMID:
17154494
13.

Antinociceptive effect of co-administered NMDA and histamine H4 receptor antagonists in a rat model of acute pain.

Wolińska R, Leśniak A, Żochowska M, Sacharczuk M, Kieć-Kononowicz K, Bujalska-Zadrożny M.

Pharmacol Rep. 2017 Apr;69(2):222-228. doi: 10.1016/j.pharep.2016.10.018. Epub 2016 Oct 29.

PMID:
28092808
14.

No evidence for histamine H4 receptor in human monocytes.

Werner K, Neumann D, Buschauer A, Seifert R.

J Pharmacol Exp Ther. 2014 Dec;351(3):519-26. doi: 10.1124/jpet.114.218107. Epub 2014 Oct 1.

15.

Molecular pharmacology of histamine H4 receptors.

Nijmeijer S, de Graaf C, Leurs R, Vischer HF.

Front Biosci (Landmark Ed). 2012 Jun 1;17:2089-106. Review.

PMID:
22652766
16.

A new generation of anti-histamines: Histamine H4 receptor antagonists on their way to the clinic.

Engelhardt H, Smits RA, Leurs R, Haaksma E, de Esch IJ.

Curr Opin Drug Discov Devel. 2009 Sep;12(5):628-43. Review.

PMID:
19736622
17.

Histamine H4 receptor ligands and their potential therapeutic applications.

Kiss R, Keseru GM.

Expert Opin Ther Pat. 2009 Feb;19(2):119-35. doi: 10.1517/13543770802691085. Review.

PMID:
19441913
18.

Conformational Restriction and Enantioseparation Increase Potency and Selectivity of Cyanoguanidine-Type Histamine H4 Receptor Agonists.

Geyer R, Nordemann U, Strasser A, Wittmann HJ, Buschauer A.

J Med Chem. 2016 Apr 14;59(7):3452-70. doi: 10.1021/acs.jmedchem.6b00120. Epub 2016 Apr 5.

PMID:
27007611
19.

Effects of histamine H4 receptor ligands in a mouse model of gastric ulceration.

Adami M, Pozzoli C, Menozzi A, Bertini S, Passeri B, Cantoni AM, Smits R, de Esch I, Leurs R, Coruzzi G.

Pharmacology. 2012;89(5-6):287-94. doi: 10.1159/000337736.

PMID:
22538763
20.

The histamine H receptor as a new target for treatment of canine inflammatory skin diseases.

Rossbach K, Stark H, Sander K, Leurs R, Kietzmann M, Bäumer W.

Vet Dermatol. 2009 Oct;20(5-6):555-61. doi: 10.1111/j.1365-3164.2009.00854.x.

PMID:
20178494

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