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Items: 1 to 20 of 218

1.

Indomethacin inhibits eosinophil migration to prostaglandin D2 : therapeutic potential of CRTH2 desensitization for eosinophilic pustular folliculitis.

Kataoka N, Satoh T, Hirai A, Saeki K, Yokozeki H.

Immunology. 2013 Sep;140(1):78-86. doi: 10.1111/imm.12112.

2.

Indomethacin-induced reduction in CRTH2 in eosinophilic pustular folliculitis (Ofuji's disease): a proposed mechanism of action.

Satoh T, Shimura C, Miyagishi C, Yokozeki H.

Acta Derm Venereol. 2010;90(1):18-22. doi: 10.2340/00015555-0759.

3.

Inhibitory effect of the 4-aminotetrahydroquinoline derivatives, selective chemoattractant receptor-homologous molecule expressed on T helper 2 cell antagonists, on eosinophil migration induced by prostaglandin D2.

Mimura H, Ikemura T, Kotera O, Sawada M, Tashiro S, Fuse E, Ueno K, Manabe H, Ohshima E, Karasawa A, Miyaji H.

J Pharmacol Exp Ther. 2005 Jul;314(1):244-51. Epub 2005 Mar 29.

4.

PGD2 induces eotaxin-3 via PPARγ from sebocytes: a possible pathogenesis of eosinophilic pustular folliculitis.

Nakahigashi K, Doi H, Otsuka A, Hirabayashi T, Murakami M, Urade Y, Zouboulis CC, Tanizaki H, Egawa G, Miyachi Y, Kabashima K.

J Allergy Clin Immunol. 2012 Feb;129(2):536-43. doi: 10.1016/j.jaci.2011.11.034. Epub 2011 Dec 28. Erratum in: J Allergy Clin Immunol. 2014 Feb;133(2):604. Zouboulis, Christos C [added].

PMID:
22206772
5.

Prostaglandin H2 induces the migration of human eosinophils through the chemoattractant receptor homologous molecule of Th2 cells, CRTH2.

Schuligoi R, Sedej M, Waldhoer M, Vukoja A, Sturm EM, Lippe IT, Peskar BA, Heinemann A.

J Leukoc Biol. 2009 Jan;85(1):136-45. doi: 10.1189/jlb.0608387. Epub 2008 Oct 3.

PMID:
18835884
6.

CRTH2-specific binding characteristics of [3H]ramatroban and its effects on PGD2-, 15-deoxy-Delta12, 14-PGJ2- and indomethacin-induced agonist responses.

Sugimoto H, Shichijo M, Okano M, Bacon KB.

Eur J Pharmacol. 2005 Nov 7;524(1-3):30-7. Epub 2005 Oct 27.

PMID:
16256979
7.

The opposing role of two prostaglandin D2 receptors, DP and CRTH2, in human eosinophil migration.

Chiba T, Ueki S, Ito W, Kato H, Kamada R, Takeda M, Kayaba H, Furue M, Chihara J.

Ann Allergy Asthma Immunol. 2011 Jun;106(6):511-7. doi: 10.1016/j.anai.2011.01.027. Epub 2011 Mar 21.

PMID:
21624751
8.

IFN-γ and TNF-α potentiate prostaglandin D2-induced human eosinophil chemotaxis through up-regulation of CRTH2 surface receptor.

El-Shazly AE, Moonen V, Mawet M, Begon D, Henket M, Arafa M, Louis R, Delvenne P, Lefebvre PP.

Int Immunopharmacol. 2011 Nov;11(11):1864-70. doi: 10.1016/j.intimp.2011.07.017. Epub 2011 Aug 9.

PMID:
21835268
9.

Effects of prostaglandin D2, 15-deoxy-Delta12,14-prostaglandin J2, and selective DP1 and DP2 receptor agonists on pulmonary infiltration of eosinophils in Brown Norway rats.

Almishri W, Cossette C, Rokach J, Martin JG, Hamid Q, Powell WS.

J Pharmacol Exp Ther. 2005 Apr;313(1):64-9. Epub 2004 Dec 8.

10.

Prostaglandin D2 induces chemotaxis in eosinophils via its receptor CRTH2 and eosinophils may cause severe ocular inflammation in patients with allergic conjunctivitis.

Fujishima H, Fukagawa K, Okada N, Takano Y, Tsubota K, Hirai H, Nagata K, Matsumoto K, Saito H.

Cornea. 2005 Nov;24(8 Suppl):S66-S70.

PMID:
16227827
11.
12.

Hierarchy of eosinophil chemoattractants: role of p38 mitogen-activated protein kinase.

Schratl P, Sturm EM, Royer JF, Sturm GJ, Lippe IT, Peskar BA, Heinemann A.

Eur J Immunol. 2006 Sep;36(9):2401-9.

13.

15R-methyl-prostaglandin D2 is a potent and selective CRTH2/DP2 receptor agonist in human eosinophils.

Monneret G, Cossette C, Gravel S, Rokach J, Powell WS.

J Pharmacol Exp Ther. 2003 Jan;304(1):349-55.

14.

Cutting edge: agonistic effect of indomethacin on a prostaglandin D2 receptor, CRTH2.

Hirai H, Tanaka K, Takano S, Ichimasa M, Nakamura M, Nagata K.

J Immunol. 2002 Feb 1;168(3):981-5.

15.

Pharmacologic profile of OC000459, a potent, selective, and orally active D prostanoid receptor 2 antagonist that inhibits mast cell-dependent activation of T helper 2 lymphocytes and eosinophils.

Pettipher R, Vinall SL, Xue L, Speight G, Townsend ER, Gazi L, Whelan CJ, Armer RE, Payton MA, Hunter MG.

J Pharmacol Exp Ther. 2012 Feb;340(2):473-82. doi: 10.1124/jpet.111.187203. Epub 2011 Nov 21.

16.

Opposing immunomodulatory roles of prostaglandin D2 during the progression of skin inflammation.

Sarashina H, Tsubosaka Y, Omori K, Aritake K, Nakagawa T, Hori M, Hirai H, Nakamura M, Narumiya S, Urade Y, Ozaki H, Murata T.

J Immunol. 2014 Jan 1;192(1):459-65. doi: 10.4049/jimmunol.1302080. Epub 2013 Dec 2.

17.

Differential modulation of human basophil functions through prostaglandin D2 receptors DP and chemoattractant receptor-homologous molecule expressed on Th2 cells/DP2.

Yoshimura-Uchiyama C, Iikura M, Yamaguchi M, Nagase H, Ishii A, Matsushima K, Yamamoto K, Shichijo M, Bacon KB, Hirai K.

Clin Exp Allergy. 2004 Aug;34(8):1283-90.

PMID:
15298571
18.

11-Dehydro-thromboxane B2, a stable thromboxane metabolite, is a full agonist of chemoattractant receptor-homologous molecule expressed on TH2 cells (CRTH2) in human eosinophils and basophils.

Böhm E, Sturm GJ, Weiglhofer I, Sandig H, Shichijo M, McNamee A, Pease JE, Kollroser M, Peskar BA, Heinemann A.

J Biol Chem. 2004 Feb 27;279(9):7663-70. Epub 2003 Dec 10.

19.

Delta12-prostaglandin D2 is a potent and selective CRTH2 receptor agonist and causes activation of human eosinophils and Th2 lymphocytes.

Gazi L, Gyles S, Rose J, Lees S, Allan C, Xue L, Jassal R, Speight G, Gamble V, Pettipher R.

Prostaglandins Other Lipid Mediat. 2005 Jan;75(1-4):153-67.

PMID:
15789622
20.

Identification of a potent and selective synthetic agonist at the CRTH2 receptor.

Gervais FG, Morello JP, Beaulieu C, Sawyer N, Denis D, Greig G, Malebranche AD, O'Neill GP.

Mol Pharmacol. 2005 Jun;67(6):1834-9. Epub 2005 Mar 8.

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