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Items: 1 to 20 of 111


Latency-associated degradation of the MRP1 drug transporter during latent human cytomegalovirus infection.

Weekes MP, Tan SY, Poole E, Talbot S, Antrobus R, Smith DL, Montag C, Gygi SP, Sinclair JH, Lehner PJ.

Science. 2013 Apr 12;340(6129):199-202. doi: 10.1126/science.1235047.


Latency-Associated Expression of Human Cytomegalovirus US28 Attenuates Cell Signaling Pathways To Maintain Latent Infection.

Krishna BA, Poole EL, Jackson SE, Smit MJ, Wills MR, Sinclair JH.

MBio. 2017 Dec 5;8(6). pii: e01754-17. doi: 10.1128/mBio.01754-17.


Human cytomegalovirus modulates monocyte-mediated innate immune responses during short-term experimental latency in vitro.

Noriega VM, Haye KK, Kraus TA, Kowalsky SR, Ge Y, Moran TM, Tortorella D.

J Virol. 2014 Aug;88(16):9391-405. doi: 10.1128/JVI.00934-14. Epub 2014 Jun 11.


Cis and trans acting factors involved in human cytomegalovirus experimental and natural latent infection of CD14 (+) monocytes and CD34 (+) cells.

Rossetto CC, Tarrant-Elorza M, Pari GS.

PLoS Pathog. 2013;9(5):e1003366. doi: 10.1371/journal.ppat.1003366. Epub 2013 May 23.


Human cytomegalovirus manipulation of latently infected cells.

Sinclair JH, Reeves MB.

Viruses. 2013 Nov 21;5(11):2803-24. doi: 10.3390/v5112803. Review.


Efficient human cytomegalovirus reactivation is maturation dependent in the Langerhans dendritic cell lineage and can be studied using a CD14+ experimental latency model.

Huang MM, Kew VG, Jestice K, Wills MR, Reeves MB.

J Virol. 2012 Aug;86(16):8507-15. doi: 10.1128/JVI.00598-12. Epub 2012 May 30.


Sleepless latency of human cytomegalovirus.

Poole E, Sinclair J.

Med Microbiol Immunol. 2015 Jun;204(3):421-9. doi: 10.1007/s00430-015-0401-6. Epub 2015 Mar 14. Review.


Human Cytomegalovirus Requires Epidermal Growth Factor Receptor Signaling To Enter and Initiate the Early Steps in the Establishment of Latency in CD34+ Human Progenitor Cells.

Kim JH, Collins-McMillen D, Buehler JC, Goodrum FD, Yurochko AD.

J Virol. 2017 Feb 14;91(5). pii: e01206-16. doi: 10.1128/JVI.01206-16. Print 2017 Mar 1.


Long and Short Isoforms of the Human Cytomegalovirus UL138 Protein Silence IE Transcription and Promote Latency.

Lee SH, Caviness K, Albright ER, Lee JH, Gelbmann CB, Rak M, Goodrum F, Kalejta RF.

J Virol. 2016 Sep 29;90(20):9483-94. doi: 10.1128/JVI.01547-16. Print 2016 Oct 15.


The myeloid transcription factor GATA-2 regulates the viral UL144 gene during human cytomegalovirus latency in an isolate-specific manner.

Poole E, Walther A, Raven K, Benedict CA, Mason GM, Sinclair J.

J Virol. 2013 Apr;87(8):4261-71. doi: 10.1128/JVI.03497-12. Epub 2013 Jan 30.


Human cytomegalovirus gene expression during infection of primary hematopoietic progenitor cells: a model for latency.

Goodrum FD, Jordan CT, High K, Shenk T.

Proc Natl Acad Sci U S A. 2002 Dec 10;99(25):16255-60. Epub 2002 Nov 27.


Human cytomegalovirus sequences expressed in latently infected individuals promote a latent infection in vitro.

Goodrum F, Reeves M, Sinclair J, High K, Shenk T.

Blood. 2007 Aug 1;110(3):937-45. Epub 2007 Apr 17.


Virally induced changes in cellular microRNAs maintain latency of human cytomegalovirus in CD34⁺ progenitors.

Poole E, McGregor Dallas SR, Colston J, Joseph RS, Sinclair J.

J Gen Virol. 2011 Jul;92(Pt 7):1539-49. doi: 10.1099/vir.0.031377-0. Epub 2011 Apr 6.


Experimental human cytomegalovirus latency in CD14+ monocytes.

Hargett D, Shenk TE.

Proc Natl Acad Sci U S A. 2010 Nov 16;107(46):20039-44. doi: 10.1073/pnas.1014509107. Epub 2010 Nov 1.


Tumor Necrosis Factor Alpha Induces Reactivation of Human Cytomegalovirus Independently of Myeloid Cell Differentiation following Posttranscriptional Establishment of Latency.

Forte E, Swaminathan S, Schroeder MW, Kim JY, Terhune SS, Hummel M.

MBio. 2018 Sep 11;9(5). pii: e01560-18. doi: 10.1128/mBio.01560-18.


Antagonistic determinants controlling replicative and latent states of human cytomegalovirus infection.

Umashankar M, Rak M, Bughio F, Zagallo P, Caviness K, Goodrum FD.

J Virol. 2014 Jun;88(11):5987-6002. doi: 10.1128/JVI.03506-13. Epub 2014 Mar 12.


HCMV protein LUNA is required for viral reactivation from latently infected primary CD14⁺ cells.

Keyes LR, Hargett D, Soland M, Bego MG, Rossetto CC, Almeida-Porada G, St Jeor S.

PLoS One. 2012;7(12):e52827. doi: 10.1371/journal.pone.0052827. Epub 2012 Dec 26.


Human cytomegalovirus latency-associated proteins elicit immune-suppressive IL-10 producing CD4⁺ T cells.

Mason GM, Jackson S, Okecha G, Poole E, Sissons JG, Sinclair J, Wills MR.

PLoS Pathog. 2013;9(10):e1003635. doi: 10.1371/journal.ppat.1003635. Epub 2013 Oct 10.


Glucocorticosteroids trigger reactivation of human cytomegalovirus from latently infected myeloid cells and increase the risk for HCMV infection in D+R+ liver transplant patients.

Van Damme E, Sauviller S, Lau B, Kesteleyn B, Griffiths P, Burroughs A, Emery V, Sinclair J, Van Loock M.

J Gen Virol. 2015 Jan;96(Pt 1):131-43. doi: 10.1099/vir.0.069872-0. Epub 2014 Oct 13.


[Latency and reactivation of HCMV].

Eizuru Y.

Nihon Rinsho. 2006 Mar;64 Suppl 3:435-9. Review. Japanese. No abstract available.


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