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Items: 1 to 20 of 74

1.

Upregulation of Nrf2 expression by human cytomegalovirus infection protects host cells from oxidative stress.

Lee J, Koh K, Kim YE, Ahn JH, Kim S.

J Gen Virol. 2013 Jul;94(Pt 7):1658-68. doi: 10.1099/vir.0.052142-0. Epub 2013 Apr 11.

PMID:
23580430
2.

Up-regulation of Nrf2-mediated heme oxygenase-1 expression by eckol, a phlorotannin compound, through activation of Erk and PI3K/Akt.

Kim KC, Kang KA, Zhang R, Piao MJ, Kim GY, Kang MY, Lee SJ, Lee NH, Surh YJ, Hyun JW.

Int J Biochem Cell Biol. 2010 Feb;42(2):297-305. doi: 10.1016/j.biocel.2009.11.009. Epub 2009 Nov 18.

PMID:
19931411
3.

A formulated red ginseng extract rescues PC12 cells from PCB-induced oxidative cell death through Nrf2-mediated upregulation of heme oxygenase-1 and glutamate cysteine ligase.

Park SH, Jang JH, Chen CY, Na HK, Surh YJ.

Toxicology. 2010 Nov 28;278(1):131-9. doi: 10.1016/j.tox.2010.04.003. Epub 2010 Apr 22.

PMID:
20399244
4.

4-Ketopinoresinol, a novel naturally occurring ARE activator, induces the Nrf2/HO-1 axis and protects against oxidative stress-induced cell injury via activation of PI3K/AKT signaling.

Chen HH, Chen YT, Huang YW, Tsai HJ, Kuo CC.

Free Radic Biol Med. 2012 Mar 15;52(6):1054-66. doi: 10.1016/j.freeradbiomed.2011.12.012. Epub 2011 Dec 24.

PMID:
22245092
5.
6.

Isorhamnetin protects against oxidative stress by activating Nrf2 and inducing the expression of its target genes.

Yang JH, Shin BY, Han JY, Kim MG, Wi JE, Kim YW, Cho IJ, Kim SC, Shin SM, Ki SH.

Toxicol Appl Pharmacol. 2014 Jan 15;274(2):293-301. doi: 10.1016/j.taap.2013.10.026. Epub 2013 Nov 7.

PMID:
24211276
7.

7,8-Dihydroxyflavone protects human keratinocytes against oxidative stress-induced cell damage via the ERK and PI3K/Akt-mediated Nrf2/HO-1 signaling pathways.

Ryu MJ, Kang KA, Piao MJ, Kim KC, Zheng J, Yao CW, Cha JW, Chung HS, Kim SC, Jung E, Park D, Chae S, Hyun JW.

Int J Mol Med. 2014 Apr;33(4):964-70. doi: 10.3892/ijmm.2014.1643. Epub 2014 Feb 4.

PMID:
24503931
8.

Resistance of neuroblastoma GI-ME-N cell line to glutathione depletion involves Nrf2 and heme oxygenase-1.

Furfaro AL, Macay JR, Marengo B, Nitti M, Parodi A, Fenoglio D, Marinari UM, Pronzato MA, Domenicotti C, Traverso N.

Free Radic Biol Med. 2012 Jan 15;52(2):488-96. doi: 10.1016/j.freeradbiomed.2011.11.007. Epub 2011 Nov 13.

PMID:
22142473
9.

C-terminal mechano-growth factor induces heme oxygenase-1-mediated neuroprotection of SH-SY5Y cells via the protein kinase Cϵ/Nrf2 pathway.

Quesada A, Ogi J, Schultz J, Handforth A.

J Neurosci Res. 2011 Mar;89(3):394-405. doi: 10.1002/jnr.22543. Epub 2011 Jan 13. Erratum in: J Neurosci Res. 2011 Jul;89(7):1142.

PMID:
21259326
10.

Pinosylvin-mediated protection against oxidative stress in human retinal pigment epithelial cells.

Koskela A, Reinisalo M, Hyttinen JM, Kaarniranta K, Karjalainen RO.

Mol Vis. 2014 Jun 2;20:760-9. eCollection 2014.

11.

Nuclear factor E2-related factor 2-dependent myocardiac cytoprotection against oxidative and electrophilic stress.

Zhu H, Jia Z, Misra BR, Zhang L, Cao Z, Yamamoto M, Trush MA, Misra HP, Li Y.

Cardiovasc Toxicol. 2008 Summer;8(2):71-85. doi: 10.1007/s12012-008-9016-0. Epub 2008 May 8.

PMID:
18463988
12.

Dietary flavonoid genistein induces Nrf2 and phase II detoxification gene expression via ERKs and PKC pathways and protects against oxidative stress in Caco-2 cells.

Zhai X, Lin M, Zhang F, Hu Y, Xu X, Li Y, Liu K, Ma X, Tian X, Yao J.

Mol Nutr Food Res. 2013 Feb;57(2):249-59. doi: 10.1002/mnfr.201200536. Epub 2012 Dec 15.

PMID:
23255485
13.

Adaphostin toxicity in a sensitive non-small cell lung cancer model is mediated through Nrf2 signaling and heme oxygenase 1.

Fer ND, Shoemaker RH, Monks A.

J Exp Clin Cancer Res. 2010 Jul 9;29:91. doi: 10.1186/1756-9966-29-91.

14.

PM2.5 induces Nrf2-mediated defense mechanisms against oxidative stress by activating PIK3/AKT signaling pathway in human lung alveolar epithelial A549 cells.

Deng X, Rui W, Zhang F, Ding W.

Cell Biol Toxicol. 2013 Jun;29(3):143-57. doi: 10.1007/s10565-013-9242-5. Epub 2013 Mar 24.

PMID:
23525690
15.

A novel small molecule, N-(4-(2-pyridyl)(1,3-thiazol-2-yl))-2-(2,4,6-trimethylphenoxy) acetamide, selectively protects against oxidative stress-induced cell death by activating the Nrf2-ARE pathway: therapeutic implications for ALS.

Kanno T, Tanaka K, Yanagisawa Y, Yasutake K, Hadano S, Yoshii F, Hirayama N, Ikeda JE.

Free Radic Biol Med. 2012 Dec 1;53(11):2028-42. doi: 10.1016/j.freeradbiomed.2012.09.010. Epub 2012 Sep 20.

PMID:
23000247
16.

Activation of nuclear factor erythroid 2-related factor 2 and PPARγ plays a role in the genistein-mediated attenuation of oxidative stress-induced endothelial cell injury.

Zhang T, Wang F, Xu HX, Yi L, Qin Y, Chang H, Mi MT, Zhang QY.

Br J Nutr. 2013 Jan 28;109(2):223-35. doi: 10.1017/S0007114512001110. Epub 2012 May 3.

PMID:
22716961
17.

The flavonoid, eriodictyol, induces long-term protection in ARPE-19 cells through its effects on Nrf2 activation and phase 2 gene expression.

Johnson J, Maher P, Hanneken A.

Invest Ophthalmol Vis Sci. 2009 May;50(5):2398-406. doi: 10.1167/iovs.08-2088. Epub 2008 Dec 30.

18.

Nrf2-dependent upregulation of antioxidative enzymes: a novel pathway for proteasome inhibitor-mediated cardioprotection.

Dreger H, Westphal K, Weller A, Baumann G, Stangl V, Meiners S, Stangl K.

Cardiovasc Res. 2009 Jul 15;83(2):354-61. doi: 10.1093/cvr/cvp107. Epub 2009 Apr 7.

PMID:
19351736
19.

Gastrodin protects against MPP(+)-induced oxidative stress by up regulates heme oxygenase-1 expression through p38 MAPK/Nrf2 pathway in human dopaminergic cells.

Jiang G, Hu Y, Liu L, Cai J, Peng C, Li Q.

Neurochem Int. 2014 Sep;75:79-88. doi: 10.1016/j.neuint.2014.06.003. Epub 2014 Jun 14.

PMID:
24932697
20.

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