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Items: 1 to 20 of 94

1.

Characterization of eicosanoid synthesis in a genetic ablation model of ceramide kinase.

Mietla JA, Wijesinghe DS, Hoeferlin LA, Shultz MD, Natarajan R, Fowler AA 3rd, Chalfant CE.

J Lipid Res. 2013 Jul;54(7):1834-47. doi: 10.1194/jlr.M035683. Epub 2013 Apr 10.

2.

Neutropenia with impaired immune response to Streptococcus pneumoniae in ceramide kinase-deficient mice.

Graf C, Zemann B, Rovina P, Urtz N, Schanzer A, Reuschel R, Mechtcheriakova D, Müller M, Fischer E, Reichel C, Huber S, Dawson J, Meingassner JG, Billich A, Niwa S, Badegruber R, Van Veldhoven PP, Kinzel B, Baumruker T, Bornancin F.

J Immunol. 2008 Mar 1;180(5):3457-66.

3.

Ceramide kinase is required for a normal eicosanoid response and the subsequent orderly migration of fibroblasts.

Wijesinghe DS, Brentnall M, Mietla JA, Hoeferlin LA, Diegelmann RF, Boise LH, Chalfant CE.

J Lipid Res. 2014 Jul;55(7):1298-309. doi: 10.1194/jlr.M048207. Epub 2014 May 13.

4.

Regulation and traffic of ceramide 1-phosphate produced by ceramide kinase: comparative analysis to glucosylceramide and sphingomyelin.

Boath A, Graf C, Lidome E, Ullrich T, Nussbaumer P, Bornancin F.

J Biol Chem. 2008 Mar 28;283(13):8517-26. Epub 2007 Dec 16.

5.

Ceramide kinase uses ceramide provided by ceramide transport protein: localization to organelles of eicosanoid synthesis.

Lamour NF, Stahelin RV, Wijesinghe DS, Maceyka M, Wang E, Allegood JC, Merrill AH Jr, Cho W, Chalfant CE.

J Lipid Res. 2007 Jun;48(6):1293-304. Epub 2007 Mar 27.

6.

Ceramide kinase and the ceramide-1-phosphate/cPLA2alpha interaction as a therapeutic target.

Lamour NF, Chalfant CE.

Curr Drug Targets. 2008 Aug;9(8):674-82. Review.

PMID:
18691014
7.

Ceramide kinase regulates the production of tumor necrosis factor α (TNFα) via inhibition of TNFα-converting enzyme.

Lamour NF, Wijesinghe DS, Mietla JA, Ward KE, Stahelin RV, Chalfant CE.

J Biol Chem. 2011 Dec 16;286(50):42808-17. doi: 10.1074/jbc.M111.310169. Epub 2011 Oct 18.

8.

Ceramide-1-phosphate: the "missing" link in eicosanoid biosynthesis and inflammation.

Lamour NF, Chalfant CE.

Mol Interv. 2005 Dec;5(6):358-67. Review.

PMID:
16394251
9.

Ceramide kinase contributes to proliferation but not to prostaglandin E2 formation in renal mesangial cells and fibroblasts.

Pastukhov O, Schwalm S, Römer I, Zangemeister-Wittke U, Pfeilschifter J, Huwiler A.

Cell Physiol Biochem. 2014;34(1):119-33. doi: 10.1159/000362989. Epub 2014 Jun 16.

10.

Ceramide kinase deficiency impairs microendothelial cell angiogenesis in vitro.

Niwa S, Graf C, Bornancin F.

Microvasc Res. 2009 May;77(3):389-93. doi: 10.1016/j.mvr.2009.01.006. Epub 2009 Feb 6.

PMID:
19323974
11.

Ceramide kinase: the first decade.

Bornancin F.

Cell Signal. 2011 Jun;23(6):999-1008. doi: 10.1016/j.cellsig.2010.11.012. Epub 2010 Nov 25. Review.

PMID:
21111813
12.

Ceramide kinase is not essential but might act as an Ca2+-sensor for mast cell activation.

Mitsutake S, Kumada H, Soga M, Hurue Y, Asanuma F, Nagira M, Deguchi M, Date T, Yokose U, Inagaki Y, Sugiura M, Kohama T, Igarashi Y.

Prostaglandins Other Lipid Mediat. 2010 Nov;93(3-4):109-12. doi: 10.1016/j.prostaglandins.2010.07.003. Epub 2010 Aug 1.

PMID:
20678580
13.

Ceramide kinase is a mediator of calcium-dependent degranulation in mast cells.

Mitsutake S, Kim TJ, Inagaki Y, Kato M, Yamashita T, Igarashi Y.

J Biol Chem. 2004 Apr 23;279(17):17570-7. Epub 2004 Feb 9.

14.

Role of cytosolic phospholipase A(2)α in cell rounding and cytotoxicity induced by ceramide-1-phosphate via ceramide kinase.

Nakamura H, Tada E, Makiyama T, Yasufuku K, Murayama T.

Arch Biochem Biophys. 2011 Aug 1;512(1):45-51. doi: 10.1016/j.abb.2011.05.006. Epub 2011 May 20.

PMID:
21621503
15.

Wild-type levels of ceramide and ceramide-1-phosphate in the retina of ceramide kinase-like-deficient mice.

Graf C, Niwa S, Müller M, Kinzel B, Bornancin F.

Biochem Biophys Res Commun. 2008 Aug 15;373(1):159-63. doi: 10.1016/j.bbrc.2008.06.002. Epub 2008 Jun 12.

PMID:
18555012
16.

The role of ceramide-1-phosphate in biological functions.

Hoeferlin LA, Wijesinghe DS, Chalfant CE.

Handb Exp Pharmacol. 2013;(215):153-66. doi: 10.1007/978-3-7091-1368-4_8. Review.

17.

Transcriptional repression of ceramide kinase in LPS-challenged macrophages.

Rovina P, Jaritz M, Bornancin F.

Biochem Biophys Res Commun. 2010 Oct 8;401(1):164-7. doi: 10.1016/j.bbrc.2010.09.041. Epub 2010 Sep 16.

PMID:
20849823
18.

Modulation of ceramide metabolism in mouse primary macrophages.

Rovina P, Graf C, Bornancin F.

Biochem Biophys Res Commun. 2010 Aug 20;399(2):150-4. doi: 10.1016/j.bbrc.2010.07.034. Epub 2010 Jul 15.

PMID:
20637730
19.

Effects of Glycerophospholipids on Ceramide Kinase Activity: Cardiolipin-Affected Cellular Formation of Ceramide-1-phosphate.

Matsuzaki W, Takahashi H, Nakamura H, Murayama T.

Biol Pharm Bull. 2016;39(10):1708-1717.

20.

Ovalbumin-induced plasma interleukin-4 levels are reduced in ceramide kinase-deficient DO11.10 RAG1-/- mice.

Niwa S, Urtz N, Baumruker T, Billich A, Bornancin F.

Lipids Health Dis. 2010 Jan 6;9:1. doi: 10.1186/1476-511X-9-1.

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