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Items: 1 to 20 of 174

1.

Impairment of triptolide on liver mitochondria in isolated liver mitochondria and HL7702 cell line.

Fu Q, Jiang ZZ, Zhang LY.

Chin J Integr Med. 2013 Sep;19(9):683-8. doi: 10.1007/s11655-012-1265-x. Epub 2013 Apr 10.

PMID:
23576275
2.

Triptolide induces apoptosis in human adrenal cancer NCI-H295 cells through a mitochondrial-dependent pathway.

Wu PP, Liu KC, Huang WW, Ma CY, Lin H, Yang JS, Chung JG.

Oncol Rep. 2011 Feb;25(2):551-7. doi: 10.3892/or.2010.1080. Epub 2010 Dec 8.

PMID:
21152873
3.

Involvement of mitochondrial pathway in triptolide-induced cytotoxicity in human normal liver L-02 cells.

Yao J, Jiang Z, Duan W, Huang J, Zhang L, Hu L, He L, Li F, Xiao Y, Shu B, Liu C.

Biol Pharm Bull. 2008 Apr;31(4):592-7.

4.

Toxicity of thallium on isolated rat liver mitochondria: the role of oxidative stress and MPT pore opening.

Eskandari MR, Mashayekhi V, Aslani M, Hosseini MJ.

Environ Toxicol. 2015 Feb;30(2):232-41. doi: 10.1002/tox.21900. Epub 2013 Aug 30.

PMID:
23996974
5.

The Ca²⁺-calmodulin-Ca²⁺/calmodulin-dependent protein kinase II signaling pathway is involved in oxidative stress-induced mitochondrial permeability transition and apoptosis in isolated rat hepatocytes.

Toledo FD, Pérez LM, Basiglio CL, Ochoa JE, Sanchez Pozzi EJ, Roma MG.

Arch Toxicol. 2014 Sep;88(9):1695-709. doi: 10.1007/s00204-014-1219-5. Epub 2014 Mar 11.

PMID:
24614978
6.

Alteration in mitochondrial thiol enhances calcium ion dependent membrane permeability transition and dysfunction in vitro: a cross-talk between mtThiol, Ca(2+), and ROS.

Singh BK, Tripathi M, Pandey PK, Kakkar P.

Mol Cell Biochem. 2011 Nov;357(1-2):373-85. doi: 10.1007/s11010-011-0908-0. Epub 2011 Jul 12.

PMID:
21748338
7.

Mitochondrial dysfunction induced by different organochalchogens is mediated by thiol oxidation and is not dependent of the classical mitochondrial permeability transition pore opening.

Puntel RL, Roos DH, Folmer V, Nogueira CW, Galina A, Aschner M, Rocha JB.

Toxicol Sci. 2010 Sep;117(1):133-43. doi: 10.1093/toxsci/kfq185. Epub 2010 Jun 23.

8.

Duality of effect of La3+ on mitochondrial permeability transition pore depending on the concentration.

Dong S, Zhao Y, Liu H, Yang X, Wang K.

Biometals. 2009 Dec;22(6):917-26. doi: 10.1007/s10534-009-9244-1.

PMID:
19399629
9.

Toxicity of copper on isolated liver mitochondria: impairment at complexes I, II, and IV leads to increased ROS production.

Hosseini MJ, Shaki F, Ghazi-Khansari M, Pourahmad J.

Cell Biochem Biophys. 2014 Sep;70(1):367-81. doi: 10.1007/s12013-014-9922-7.

PMID:
24691927
10.

Vanadium compounds induced mitochondria permeability transition pore (PTP) opening related to oxidative stress.

Zhao Y, Ye L, Liu H, Xia Q, Zhang Y, Yang X, Wang K.

J Inorg Biochem. 2010 Apr;104(4):371-8. doi: 10.1016/j.jinorgbio.2009.11.007. Epub 2009 Nov 27.

PMID:
20015552
11.

Activation of SIRT3 attenuates triptolide-induced toxicity through closing mitochondrial permeability transition pore in cardiomyocytes.

Yang Y, Wang W, Xiong Z, Kong J, Qiu Y, Shen F, Huang Z.

Toxicol In Vitro. 2016 Aug;34:128-37. doi: 10.1016/j.tiv.2016.03.020. Epub 2016 Apr 8.

PMID:
27064125
12.

Triptolide induces S phase arrest via the inhibition of cyclin E and CDC25A and triggers apoptosis via caspase- and mitochondrial-dependent signaling pathways in A375.S2 human melanoma cells.

Hung FM, Chen YL, Huang AC, Hsiao YP, Yang JS, Chung MT, Chueh FS, Lu HF, Chung JG.

Oncol Rep. 2013 Mar;29(3):1053-60. doi: 10.3892/or.2013.2230. Epub 2013 Jan 8.

PMID:
23314229
13.

Cyclosporin A-induced oxidative stress is not the consequence of an increase in mitochondrial membrane potential.

van der Toorn M, Kauffman HF, van der Deen M, Slebos DJ, Koëter GH, Gans RO, Bakker SJ.

FEBS J. 2007 Jun;274(12):3003-12. Epub 2007 May 17.

14.

Effect of garlic-derived organosulfur compounds on mitochondrial function and integrity in isolated mouse liver mitochondria.

Caro AA, Adlong LW, Crocker SJ, Gardner MW, Luikart EF, Gron LU.

Toxicol Lett. 2012 Oct 17;214(2):166-74. doi: 10.1016/j.toxlet.2012.08.017. Epub 2012 Aug 29.

15.

Dimethylaminopyridine derivatives of lupane triterpenoids cause mitochondrial disruption and induce the permeability transition.

Bernardo TC, Cunha-Oliveira T, Serafim TL, Holy J, Krasutsky D, Kolomitsyna O, Krasutsky P, Moreno AM, Oliveira PJ.

Bioorg Med Chem. 2013 Dec 1;21(23):7239-49. doi: 10.1016/j.bmc.2013.09.066. Epub 2013 Oct 8.

PMID:
24156937
16.

Triptolide inactivates Akt and induces caspase-dependent death in cervical cancer cells via the mitochondrial pathway.

Kim MJ, Lee TH, Kim SH, Choi YJ, Heo J, Kim YH.

Int J Oncol. 2010 Nov;37(5):1177-85.

PMID:
20878065
17.

The roles of endogenous reactive oxygen species and nitric oxide in triptolide-induced apoptotic cell death in macrophages.

Bao X, Cui J, Wu Y, Han X, Gao C, Hua Z, Shen P.

J Mol Med (Berl). 2007 Jan;85(1):85-98. Epub 2006 Nov 16.

PMID:
17109129
18.

Effects of extracts of the leaves of Brysocarpus coccineus on rat liver mitochondrial membrane permeability transition (MMPT) pore.

Adedosu OT, Adejoke TT, Salako OO, Olorunsogo OO.

Afr J Med Med Sci. 2012 Dec;41 Suppl:125-32.

PMID:
23678647
19.

Nimesulide aggravates redox imbalance and calcium dependent mitochondrial permeability transition leading to dysfunction in vitro.

Singh BK, Tripathi M, Pandey PK, Kakkar P.

Toxicology. 2010 Sep 10;275(1-3):1-9. doi: 10.1016/j.tox.2010.05.001. Epub 2010 May 8.

PMID:
20457212
20.

Flufenamic acid as an inducer of mitochondrial permeability transition.

Jordani MC, Santos AC, Prado IM, Uyemura SA, Curti C.

Mol Cell Biochem. 2000 Jul;210(1-2):153-8.

PMID:
10976768

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