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Items: 1 to 20 of 185

1.

DICO, a novel nonaromatic B-ring flavonoid, induces G2/M cell cycle arrest and apoptosis in human hepatoma cells.

Zhou D, Wei A, Cao C, Ruan J.

Food Chem Toxicol. 2013 Jul;57:322-9. doi: 10.1016/j.fct.2013.03.032. Epub 2013 Apr 6.

PMID:
23567243
2.

Benzyl isothiocyanate (BITC) induces G2/M phase arrest and apoptosis in human melanoma A375.S2 cells through reactive oxygen species (ROS) and both mitochondria-dependent and death receptor-mediated multiple signaling pathways.

Huang SH, Wu LW, Huang AC, Yu CC, Lien JC, Huang YP, Yang JS, Yang JH, Hsiao YP, Wood WG, Yu CS, Chung JG.

J Agric Food Chem. 2012 Jan 18;60(2):665-75. doi: 10.1021/jf204193v. Epub 2012 Jan 6.

PMID:
22148415
3.

GL-V9, a newly synthetic flavonoid derivative, induces mitochondrial-mediated apoptosis and G2/M cell cycle arrest in human hepatocellular carcinoma HepG2 cells.

Li L, Lu N, Dai Q, Wei L, Zhao Q, Li Z, He Q, Dai Y, Guo Q.

Eur J Pharmacol. 2011 Nov 16;670(1):13-21. doi: 10.1016/j.ejphar.2011.08.054. Epub 2011 Sep 17.

PMID:
21944925
4.

Anti-tumor effect of germacrone on human hepatoma cell lines through inducing G2/M cell cycle arrest and promoting apoptosis.

Liu Y, Wang W, Fang B, Ma F, Zheng Q, Deng P, Zhao S, Chen M, Yang G, He G.

Eur J Pharmacol. 2013 Jan 5;698(1-3):95-102. doi: 10.1016/j.ejphar.2012.10.013. Epub 2012 Oct 29.

PMID:
23117090
5.

Lignans extracted from Vitex negundo possess cytotoxic activity by G2/M phase cell cycle arrest and apoptosis induction.

Xin H, Kong Y, Wang Y, Zhou Y, Zhu Y, Li D, Tan W.

Phytomedicine. 2013 May 15;20(7):640-7. doi: 10.1016/j.phymed.2013.02.002. Epub 2013 Apr 3.

PMID:
23562365
6.

SKLB316, a novel small-molecule inhibitor of cell-cycle progression, induces G2/M phase arrest and apoptosis in vitro and inhibits tumor growth in vivo.

Xia Y, Lei Q, Zhu Y, Ye T, Wang N, Li G, Shi X, Liu Y, Shao B, Yin T, Zhao L, Wu W, Song X, Xiong Y, Wei Y, Yu L.

Cancer Lett. 2014 Dec 28;355(2):297-309. doi: 10.1016/j.canlet.2014.09.042. Epub 2014 Oct 7.

PMID:
25301449
7.

Millepachine, a novel chalcone, induces G2/M arrest by inhibiting CDK1 activity and causing apoptosis via ROS-mitochondrial apoptotic pathway in human hepatocarcinoma cells in vitro and in vivo.

Wu W, Ye H, Wan L, Han X, Wang G, Hu J, Tang M, Duan X, Fan Y, He S, Huang L, Pei H, Wang X, Li X, Xie C, Zhang R, Yuan Z, Mao Y, Wei Y, Chen L.

Carcinogenesis. 2013 Jul;34(7):1636-43. doi: 10.1093/carcin/bgt087. Epub 2013 Mar 7.

PMID:
23471882
8.

Morin inhibits the growth of human leukemia HL-60 cells via cell cycle arrest and induction of apoptosis through mitochondria dependent pathway.

Kuo HM, Chang LS, Lin YL, Lu HF, Yang JS, Lee JH, Chung JG.

Anticancer Res. 2007 Jan-Feb;27(1A):395-405.

9.
11.

Inhibitory effect of oleanolic acid on hepatocellular carcinoma via ERK-p53-mediated cell cycle arrest and mitochondrial-dependent apoptosis.

Wang X, Bai H, Zhang X, Liu J, Cao P, Liao N, Zhang W, Wang Z, Hai C.

Carcinogenesis. 2013 Jun;34(6):1323-30. doi: 10.1093/carcin/bgt058. Epub 2013 Feb 12.

PMID:
23404993
12.

The synthesized 2-(2-fluorophenyl)-6,7-methylenedioxyquinolin-4-one (CHM-1) promoted G2/M arrest through inhibition of CDK1 and induced apoptosis through the mitochondrial-dependent pathway in CT-26 murine colorectal adenocarcinoma cells.

Chou LC, Yang JS, Huang LJ, Wu HC, Lu CC, Chiang JH, Chen KT, Kuo SC, Chung JG.

J Gastroenterol. 2009;44(10):1055-63. doi: 10.1007/s00535-009-0111-1. Epub 2009 Aug 14.

PMID:
19688288
13.

Induction of G2/M phase cell cycle arrest and apoptosis by ginsenoside Rf in human osteosarcoma MG‑63 cells through the mitochondrial pathway.

Shangguan WJ, Li H, Zhang YH.

Oncol Rep. 2014 Jan;31(1):305-13. doi: 10.3892/or.2013.2815. Epub 2013 Oct 24.

PMID:
24173574
14.

Bufotalin from Venenum Bufonis inhibits growth of multidrug resistant HepG2 cells through G2/M cell cycle arrest and apoptosis.

Zhang DM, Liu JS, Tang MK, Yiu A, Cao HH, Jiang L, Chan JY, Tian HY, Fung KP, Ye WC.

Eur J Pharmacol. 2012 Oct 5;692(1-3):19-28. doi: 10.1016/j.ejphar.2012.06.045. Epub 2012 Jul 25.

PMID:
22841670
15.

[Induction of G2 /M phase arrest and apoptosis of MCF-7 cells by novel benzofuran lignan via suppressing cell cycle proteins].

Yang H, Cai YC, Pang JY, Li YQ, Zeng ZL, Xu ZL, Xian LJ.

Yao Xue Xue Bao. 2008 Feb;43(2):138-44. Chinese.

PMID:
18507339
16.

Longikaurin A, a natural ent-kaurane, induces G2/M phase arrest via downregulation of Skp2 and apoptosis induction through ROS/JNK/c-Jun pathway in hepatocellular carcinoma cells.

Liao YJ, Bai HY, Li ZH, Zou J, Chen JW, Zheng F, Zhang JX, Mai SJ, Zeng MS, Sun HD, Pu JX, Xie D.

Cell Death Dis. 2014 Mar 20;5:e1137. doi: 10.1038/cddis.2014.66.

18.

Alpinetin promotes Bax translocation, induces apoptosis through the mitochondrial pathway and arrests human gastric cancer cells at the G2/M phase.

Wang Z, Lu W, Li Y, Tang B.

Mol Med Rep. 2013 Mar;7(3):915-20. doi: 10.3892/mmr.2012.1243. Epub 2012 Dec 18.

PMID:
23254270
19.

ERK-modulated intrinsic signaling and G(2)/M phase arrest contribute to the induction of apoptotic death by allyl isothiocyanate in MDA-MB-468 human breast adenocarcinoma cells.

Tsai SC, Huang WW, Huang WC, Lu CC, Chiang JH, Peng SF, Chung JG, Lin YH, Hsu YM, Amagaya S, Yang JS.

Int J Oncol. 2012 Dec;41(6):2065-72. doi: 10.3892/ijo.2012.1640. Epub 2012 Sep 24.

PMID:
23008020
20.

12-Deoxyphorbol 13-palmitate mediated cell growth inhibition, G2-M cell cycle arrest and apoptosis in BGC823 cells.

Xu HY, Chen ZW, Li H, Zhou L, Liu F, Lv YY, Liu JC.

Eur J Pharmacol. 2013 Jan 30;700(1-3):13-22. doi: 10.1016/j.ejphar.2012.11.015. Epub 2012 Dec 7.

PMID:
23220710

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