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Items: 1 to 20 of 100

1.

Rapamycin preserves the follicle pool reserve and prolongs the ovarian lifespan of female rats via modulating mTOR activation and sirtuin expression.

Zhang XM, Li L, Xu JJ, Wang N, Liu WJ, Lin XH, Fu YC, Luo LL.

Gene. 2013 Jul 1;523(1):82-7. doi: 10.1016/j.gene.2013.03.039. Epub 2013 Apr 6.

PMID:
23566837
2.

Obesity accelerates ovarian follicle development and follicle loss in rats.

Wang N, Luo LL, Xu JJ, Xu MY, Zhang XM, Zhou XL, Liu WJ, Fu YC.

Metabolism. 2014 Jan;63(1):94-103. doi: 10.1016/j.metabol.2013.09.001. Epub 2013 Oct 14.

PMID:
24135502
3.

SIRT1 activator (SRT1720) improves the follicle reserve and prolongs the ovarian lifespan of diet-induced obesity in female mice via activating SIRT1 and suppressing mTOR signaling.

Zhou XL, Xu JJ, Ni YH, Chen XC, Zhang HX, Zhang XM, Liu WJ, Luo LL, Fu YC.

J Ovarian Res. 2014 Oct 21;7:97. doi: 10.1186/s13048-014-0097-z.

4.

Rapamycin prolongs female reproductive lifespan.

Luo LL, Xu JJ, Fu YC.

Cell Cycle. 2013 Nov 1;12(21):3353-4. doi: 10.4161/cc.26578. Epub 2013 Sep 23. No abstract available.

5.

Caloric restriction promotes the reserve of follicle pool in adult female rats by inhibiting the activation of mammalian target of rapamycin signaling.

Li L, Fu YC, Xu JJ, Lin XH, Chen XC, Zhang XM, Luo LL.

Reprod Sci. 2015 Jan;22(1):60-7. doi: 10.1177/1933719114542016. Epub 2014 Jul 6.

6.

Rapamycin-sensitive mTORC1 signaling is involved in physiological primordial follicle activation in mouse ovary.

Tong Y, Li F, Lu Y, Cao Y, Gao J, Liu J.

Mol Reprod Dev. 2013 Dec;80(12):1018-34.

PMID:
24123525
7.

The effects of caloric restriction and a high-fat diet on ovarian lifespan and the expression of SIRT1 and SIRT6 proteins in rats.

Luo LL, Chen XC, Fu YC, Xu JJ, Li L, Lin XH, Xiang YF, Zhang XM.

Aging Clin Exp Res. 2012 Apr;24(2):125-33. doi: 10.3275/7660. Epub 2011 Apr 14.

PMID:
21502801
8.

New strategy for in vitro activation of primordial follicles with mTOR and PI3K stimulators.

Sun X, Su Y, He Y, Zhang J, Liu W, Zhang H, Hou Z, Liu J, Li J.

Cell Cycle. 2015;14(5):721-31. doi: 10.1080/15384101.2014.995496.

9.
10.

The effects of melatonin on oxidative stress and prevention of primordial follicle loss via activation of mTOR pathway in the rat ovary.

Behram Kandemir Y, Aydin C, Gorgisen G.

Cell Mol Biol (Noisy-le-grand). 2017 Feb 28;63(2):100-106. doi: 10.14715/cmb/2017.63.2.16.

PMID:
28364790
11.

Transforming growth factor-β signaling participates in the maintenance of the primordial follicle pool in the mouse ovary.

Wang ZP, Mu XY, Guo M, Wang YJ, Teng Z, Mao GP, Niu WB, Feng LZ, Zhao LH, Xia GL.

J Biol Chem. 2014 Mar 21;289(12):8299-311. doi: 10.1074/jbc.M113.532952. Epub 2014 Feb 10.

12.

[Effect of granulocyte-macrophage colony-stimulating factor on the mammalian target of sirolimus signaling pathway in the wound of rat].

Cui WH, Huang H, Xu X, Guo M, Dai H, Jian Y, Guo W, Xing W, Jiang JX, Yang R.

Zhonghua Shao Shang Za Zhi. 2012 Feb;28(1):36-41. Chinese.

PMID:
22490538
13.

[Effects of acupuncture on PI3K/Akt/mTOR signaling pathway in rats with premature ovarian failure].

Zhang Y, Yu B, Chen J, Zhao Z, Wang Jiali, Huang F, Lin Y, Wang M, Zhang Y, Wei B.

Zhongguo Zhen Jiu. 2015 Jan;35(1):53-8. Chinese.

PMID:
25906570
14.

Pharmacological inhibition of mTORC1 prevents over-activation of the primordial follicle pool in response to elevated PI3K signaling.

Adhikari D, Risal S, Liu K, Shen Y.

PLoS One. 2013;8(1):e53810. doi: 10.1371/journal.pone.0053810. Epub 2013 Jan 11.

15.

Rapamycin has paradoxical effects on S6 phosphorylation in rats with and without seizures.

Chen L, Hu L, Dong JY, Ye Q, Hua N, Wong M, Zeng LH.

Epilepsia. 2012 Nov;53(11):2026-33. doi: 10.1111/epi.12013.

16.

Cellular and molecular regulation of the activation of mammalian primordial follicles: somatic cells initiate follicle activation in adulthood.

Zhang H, Liu K.

Hum Reprod Update. 2015 Nov-Dec;21(6):779-86. doi: 10.1093/humupd/dmv037. Epub 2015 Jul 30. Review.

PMID:
26231759
17.

PDK1 signaling in oocytes controls reproductive aging and lifespan by manipulating the survival of primordial follicles.

Reddy P, Adhikari D, Zheng W, Liang S, Hämäläinen T, Tohonen V, Ogawa W, Noda T, Volarevic S, Huhtaniemi I, Liu K.

Hum Mol Genet. 2009 Aug 1;18(15):2813-24. doi: 10.1093/hmg/ddp217. Epub 2009 May 7.

PMID:
19423553
18.

Calorie restriction inhibits ovarian follicle development and follicle loss through activating SIRT1 signaling in mice.

Liu WJ, Zhang XM, Wang N, Zhou XL, Fu YC, Luo LL.

Eur J Med Res. 2015 Mar 12;20:22. doi: 10.1186/s40001-015-0114-8.

19.

Effects of plant polyphenols on ovarian follicular reserve in aging rats.

Chen ZG, Luo LL, Xu JJ, Zhuang XL, Kong XX, Fu YC.

Biochem Cell Biol. 2010 Aug;88(4):737-45. doi: 10.1139/O10-012.

PMID:
20651847
20.

Platelet-derived growth factor modulates the primordial to primary follicle transition.

Nilsson EE, Detzel C, Skinner MK.

Reproduction. 2006 Jun;131(6):1007-15.

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