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The flow dependency of Tie2 expression in endotoxemia.

Kurniati NF, Jongman RM, vom Hagen F, Spokes KC, Moser J, Regan ER, Krenning G, Moonen JR, Harmsen MC, Struys MM, Hammes HP, Zijlstra JG, Aird WC, Heeringa P, Molema G, van Meurs M.

Intensive Care Med. 2013 Jul;39(7):1262-71. doi: 10.1007/s00134-013-2899-7. Epub 2013 Apr 6.


Shock-induced stress induces loss of microvascular endothelial Tie2 in the kidney which is not associated with reduced glomerular barrier function.

van Meurs M, Kurniati NF, Wulfert FM, Asgeirsdottir SA, de Graaf IA, Satchell SC, Mathieson PW, Jongman RM, Kümpers P, Zijlstra JG, Heeringa P, Molema G.

Am J Physiol Renal Physiol. 2009 Aug;297(2):F272-81. doi: 10.1152/ajprenal.00137.2009. Epub 2009 Jun 10.


Histone Deacetylase Inhibition and IκB Kinase/Nuclear Factor-κB Blockade Ameliorate Microvascular Proinflammatory Responses Associated With Hemorrhagic Shock/Resuscitation in Mice.

Li R, Aslan A, Yan R, Jongman RM, Moser J, Zwiers PJ, Moorlag HE, Zijlstra JG, Molema G, van Meurs M.

Crit Care Med. 2015 Dec;43(12):e567-80. doi: 10.1097/CCM.0000000000001203.


[Inhibitory effects of Kukoamine B on the inflammatory response of small intestine in lipopolysaccharide-induced septic mice and its potential mechanisms].

Lyu W, Qin W, Zhang J, Shen W, Wang X, Sun B.

Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2015 Feb;27(2):121-6. doi: 10.3760/cma.j.issn.2095-4352.2015.02.009. Chinese.


Lipopolysaccharide (LPS)-mediated angiopoietin-2-dependent autocrine angiogenesis is regulated by NADPH oxidase 2 (Nox2) in human pulmonary microvascular endothelial cells.

Menden H, Welak S, Cossette S, Ramchandran R, Sampath V.

J Biol Chem. 2015 Feb 27;290(9):5449-61. doi: 10.1074/jbc.M114.600692. Epub 2015 Jan 7.


Sevoflurane inhibits nuclear factor-κB activation in lipopolysaccharide-induced acute inflammatory lung injury via toll-like receptor 4 signaling.

Sun XJ, Li XQ, Wang XL, Tan WF, Wang JK.

PLoS One. 2015 Apr 14;10(4):e0122752. doi: 10.1371/journal.pone.0122752. eCollection 2015.


Phospholipase C-δ(1) regulates interleukin-1β and tumor necrosis factor-α mRNA expression.

Chung E, Jakinovich P, Bae A, Rebecchi M.

Exp Cell Res. 2012 Oct 1;318(16):1987-93. doi: 10.1016/j.yexcr.2012.06.010. Epub 2012 Jun 16.


In vivo vitamin E administration attenuates interleukin-6 and interleukin-1beta responses to an acute inflammatory insult in mouse skeletal and cardiac muscle.

Huey KA, Fiscus G, Richwine AF, Johnson RW, Meador BM.

Exp Physiol. 2008 Dec;93(12):1263-72. doi: 10.1113/expphysiol.2008.043190. Epub 2008 Jun 27.


Tyrosol exhibits negative regulatory effects on LPS response and endotoxemia.

Lu J, Huang G, Wang Z, Zhuang S, Xu L, Song B, Xiong Y, Guan S.

Food Chem Toxicol. 2013 Dec;62:172-8. doi: 10.1016/j.fct.2013.08.031. Epub 2013 Aug 27.


α-Solanine Isolated From Solanum Tuberosum L. cv Jayoung Abrogates LPS-Induced Inflammatory Responses Via NF-κB Inactivation in RAW 264.7 Macrophages and Endotoxin-Induced Shock Model in Mice.

Shin JS, Lee KG, Lee HH, Lee HJ, An HJ, Nam JH, Jang DS, Lee KT.

J Cell Biochem. 2016 Oct;117(10):2327-39. doi: 10.1002/jcb.25530. Epub 2016 Mar 11.


Angiopoietin-1/Tie2 signaling pathway inhibits lipopolysaccharide-induced activation of RAW264.7 macrophage cells.

Gu H, Cui M, Bai Y, Chen F, Ma K, Zhou C, Guo L.

Biochem Biophys Res Commun. 2010 Feb 5;392(2):178-82. doi: 10.1016/j.bbrc.2010.01.009. Epub 2010 Jan 7.


Geniposide suppresses LPS-induced nitric oxide, PGE2 and inflammatory cytokine by downregulating NF-κB, MAPK and AP-1 signaling pathways in macrophages.

Shi Q, Cao J, Fang L, Zhao H, Liu Z, Ran J, Zheng X, Li X, Zhou Y, Ge D, Zhang H, Wang L, Ran Y, Fu J.

Int Immunopharmacol. 2014 Jun;20(2):298-306. doi: 10.1016/j.intimp.2014.04.004. Epub 2014 Apr 13.


Resveratrol inhibits inflammatory responses via the mammalian target of rapamycin signaling pathway in cultured LPS-stimulated microglial cells.

Zhong LM, Zong Y, Sun L, Guo JZ, Zhang W, He Y, Song R, Wang WM, Xiao CJ, Lu D.

PLoS One. 2012;7(2):e32195. doi: 10.1371/journal.pone.0032195. Epub 2012 Feb 21.


Anti-inflammatory effect of the six compounds isolated from Nauclea officinalis Pierrc ex Pitard, and molecular mechanism of strictosamide via suppressing the NF-κB and MAPK signaling pathway in LPS-induced RAW 264.7 macrophages.

Li D, Chen J, Ye J, Zhai X, Song J, Jiang C, Wang J, Zhang H, Jia X, Zhu F.

J Ethnopharmacol. 2017 Jan 20;196:66-74. doi: 10.1016/j.jep.2016.12.007. Epub 2016 Dec 15.


Bone marrow and nonbone marrow Toll like receptor 4 regulate acute hepatic injury induced by endotoxemia.

Hochhauser E, Avlas O, Fallach R, Bachmetov L, Zemel R, Pappo O, Shainberg A, Ben Ari Z.

PLoS One. 2013 Aug 15;8(8):e73041. doi: 10.1371/journal.pone.0073041. eCollection 2013.


Shear stress-induced activation of Tie2-dependent signaling pathway enhances reendothelialization capacity of early endothelial progenitor cells.

Yang Z, Xia WH, Zhang YY, Xu SY, Liu X, Zhang XY, Yu BB, Qiu YX, Tao J.

J Mol Cell Cardiol. 2012 May;52(5):1155-63. doi: 10.1016/j.yjmcc.2012.01.019. Epub 2012 Feb 1.


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