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Items: 1 to 20 of 106

1.

Ataxin-3 protects cells against H2O2-induced oxidative stress by enhancing the interaction between Bcl-X(L) and Bax.

Zhou L, Wang H, Wang P, Ren H, Chen D, Ying Z, Wang G.

Neuroscience. 2013 Jul 23;243:14-21. doi: 10.1016/j.neuroscience.2013.03.047. Epub 2013 Apr 2.

PMID:
23562578
2.

Polyglutamine-expanded ataxin-3 activates mitochondrial apoptotic pathway by upregulating Bax and downregulating Bcl-xL.

Chou AH, Yeh TH, Kuo YL, Kao YC, Jou MJ, Hsu CY, Tsai SR, Kakizuka A, Wang HL.

Neurobiol Dis. 2006 Feb;21(2):333-45. Epub 2005 Aug 19.

PMID:
16112867
3.

Polyglutamine-expanded ataxin-7 activates mitochondrial apoptotic pathway of cerebellar neurons by upregulating Bax and downregulating Bcl-x(L).

Wang HL, Yeh TH, Chou AH, Kuo YL, Luo LJ, He CY, Huang PC, Li AH.

Cell Signal. 2006 Apr;18(4):541-52. Epub 2005 Jun 16.

PMID:
15964171
4.

p53 activation mediates polyglutamine-expanded ataxin-3 upregulation of Bax expression in cerebellar and pontine nuclei neurons.

Chou AH, Lin AC, Hong KY, Hu SH, Chen YL, Chen JY, Wang HL.

Neurochem Int. 2011 Feb;58(2):145-52. doi: 10.1016/j.neuint.2010.11.005. Epub 2010 Nov 16.

PMID:
21092747
5.

Casein kinase 2 interacts with and phosphorylates ataxin-3.

Tao RS, Fei EK, Ying Z, Wang HF, Wang GH.

Neurosci Bull. 2008 Oct;24(5):271-7. doi: 10.1007/s12264-008-0605-5.

PMID:
18839019
6.

RACK1 promotes Bax oligomerization and dissociates the interaction of Bax and Bcl-XL.

Wu Y, Wang Y, Sun Y, Zhang L, Wang D, Ren F, Chang D, Chang Z, Jia B.

Cell Signal. 2010 Oct;22(10):1495-501. doi: 10.1016/j.cellsig.2010.05.018. Epub 2010 Jun 10.

PMID:
20541605
7.

CDK5 protects from caspase-induced Ataxin-3 cleavage and neurodegeneration.

Liman J, Deeg S, Voigt A, Voßfeldt H, Dohm CP, Karch A, Weishaupt J, Schulz JB, Bähr M, Kermer P.

J Neurochem. 2014 Jun;129(6):1013-23. doi: 10.1111/jnc.12684. Epub 2014 Mar 24.

8.

FOXO4-dependent upregulation of superoxide dismutase-2 in response to oxidative stress is impaired in spinocerebellar ataxia type 3.

Araujo J, Breuer P, Dieringer S, Krauss S, Dorn S, Zimmermann K, Pfeifer A, Klockgether T, Wuellner U, Evert BO.

Hum Mol Genet. 2011 Aug 1;20(15):2928-41. doi: 10.1093/hmg/ddr197. Epub 2011 May 2.

9.

Flanking domain stability modulates the aggregation kinetics of a polyglutamine disease protein.

Saunders HM, Gilis D, Rooman M, Dehouck Y, Robertson AL, Bottomley SP.

Protein Sci. 2011 Oct;20(10):1675-81. doi: 10.1002/pro.698. Epub 2011 Aug 18.

10.

Ataxin-1 poly(Q)-induced proteotoxic stress and apoptosis are attenuated in neural cells by docosahexaenoic acid-derived neuroprotectin D1.

Calandria JM, Mukherjee PK, de Rivero Vaccari JC, Zhu M, Petasis NA, Bazan NG.

J Biol Chem. 2012 Jul 6;287(28):23726-39. doi: 10.1074/jbc.M111.287078. Epub 2012 Apr 16.

11.

p62/sequestosome 1 regulates aggresome formation of pathogenic ataxin-3 with expanded polyglutamine.

Zhou L, Wang H, Chen D, Gao F, Ying Z, Wang G.

Int J Mol Sci. 2014 Aug 25;15(9):14997-5010. doi: 10.3390/ijms150914997.

12.

p45, an ATPase subunit of the 19S proteasome, targets the polyglutamine disease protein ataxin-3 to the proteasome.

Wang H, Jia N, Fei E, Wang Z, Liu C, Zhang T, Fan J, Wu M, Chen L, Nukina N, Zhou J, Wang G.

J Neurochem. 2007 Jun;101(6):1651-61. Epub 2007 Feb 14.

13.

Proteotoxic stress increases nuclear localization of ataxin-3.

Reina CP, Zhong X, Pittman RN.

Hum Mol Genet. 2010 Jan 15;19(2):235-49. doi: 10.1093/hmg/ddp482. Epub 2009 Oct 19.

14.

Interaction of ataxin-3 with huntingtin-associated protein 1 through Josephin domain.

Takeshita Y, Fujinaga R, Kokubu K, Islam MN, Jahan MR, Yanai A, Kakizuka A, Shinoda K.

Neuroreport. 2011 Mar 30;22(5):232-8. doi: 10.1097/WNR.0b013e32834505f4.

PMID:
21386698
15.

Neuroprotectin D1 induces dephosphorylation of Bcl-xL in a PP2A-dependent manner during oxidative stress and promotes retinal pigment epithelial cell survival.

Antony R, Lukiw WJ, Bazan NG.

J Biol Chem. 2010 Jun 11;285(24):18301-8. doi: 10.1074/jbc.M109.095232. Epub 2010 Apr 2.

16.

Research on screening and identification of proteins interacting with ataxin-3.

Shen L, Tang JG, Tang BS, Jiang H, Zhao GH, Xia K, Zhang YH, Cai F, Tan LM, Pan Q.

Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2005 Jun;22(3):242-7.

PMID:
15952105
17.
18.

Bcl-xl does not have to bind Bax to protect T cells from death.

Liu X, Zhu Y, Dai S, White J, Peyerl F, Kappler JW, Marrack P.

J Exp Med. 2006 Dec 25;203(13):2953-61. Epub 2006 Dec 11.

19.

Oxidative stimuli affect polyglutamine aggregation and cell death in human mutant ataxin-1-expressing cells.

Kim SJ, Kim TS, Hong S, Rhim H, Kim IY, Kang S.

Neurosci Lett. 2003 Sep 4;348(1):21-4.

PMID:
12893416
20.

BimL directly neutralizes Bcl-xL to promote Bax activation during UV-induced apoptosis.

Wang X, Xing D, Liu L, Chen WR.

FEBS Lett. 2009 Jun 18;583(12):1873-9. doi: 10.1016/j.febslet.2009.04.045. Epub 2009 May 8.

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