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Items: 1 to 20 of 100

1.

Frameshift-derived neoantigens constitute immunotherapeutic targets for patients with microsatellite-instable haematological malignancies: frameshift peptides for treating MSI+ blood cancers.

Maletzki C, Schmidt F, Dirks WG, Schmitt M, Linnebacher M.

Eur J Cancer. 2013 Jul;49(11):2587-95. doi: 10.1016/j.ejca.2013.02.035. Epub 2013 Apr 2.

PMID:
23561850
2.

An MSI tumor specific frameshift mutation in a coding microsatellite of MSH3 encodes for HLA-A0201-restricted CD8+ cytotoxic T cell epitopes.

Garbe Y, Maletzki C, Linnebacher M.

PLoS One. 2011;6(11):e26517. doi: 10.1371/journal.pone.0026517. Epub 2011 Nov 14.

3.

Immunogenic peptides generated by frameshift mutations in DNA mismatch repair-deficient cancer cells.

Schwitalle Y, Linnebacher M, Ripberger E, Gebert J, von Knebel Doeberitz M.

Cancer Immun. 2004 Nov 25;4:14.

4.

Serum antibodies against frameshift peptides in microsatellite unstable colorectal cancer patients with Lynch syndrome.

Reuschenbach M, Kloor M, Morak M, Wentzensen N, Germann A, Garbe Y, Tariverdian M, Findeisen P, Neumaier M, Holinski-Feder E, von Knebel Doeberitz M.

Fam Cancer. 2010 Jun;9(2):173-9. doi: 10.1007/s10689-009-9307-z.

5.

Frameshift peptide-derived T-cell epitopes: a source of novel tumor-specific antigens.

Linnebacher M, Gebert J, Rudy W, Woerner S, Yuan YP, Bork P, von Knebel Doeberitz M.

Int J Cancer. 2001 Jul 1;93(1):6-11.

6.

T cell responses against microsatellite instability-induced frameshift peptides and influence of regulatory T cells in colorectal cancer.

Bauer K, Nelius N, Reuschenbach M, Koch M, Weitz J, Steinert G, Kopitz J, Beckhove P, Tariverdian M, von Knebel Doeberitz M, Kloor M.

Cancer Immunol Immunother. 2013 Jan;62(1):27-37. doi: 10.1007/s00262-012-1303-8. Epub 2012 Jun 23.

PMID:
22729559
7.

Opportunities for immunotherapy in microsatellite instable colorectal cancer.

Westdorp H, Fennemann FL, Weren RD, Bisseling TM, Ligtenberg MJ, Figdor CG, Schreibelt G, Hoogerbrugge N, Wimmers F, de Vries IJ.

Cancer Immunol Immunother. 2016 Oct;65(10):1249-59. doi: 10.1007/s00262-016-1832-7. Epub 2016 Apr 8. Review.

8.

Immune response against frameshift-induced neopeptides in HNPCC patients and healthy HNPCC mutation carriers.

Schwitalle Y, Kloor M, Eiermann S, Linnebacher M, Kienle P, Knaebel HP, Tariverdian M, Benner A, von Knebel Doeberitz M.

Gastroenterology. 2008 Apr;134(4):988-97. doi: 10.1053/j.gastro.2008.01.015. Epub 2008 Jan 11.

PMID:
18395080
9.

Microsatellite instability and novel mismatch repair gene mutations in northern Chinese population with hereditary non-polyposis colorectal cancer.

Sheng JQ, Chan TL, Chan YW, Huang JS, Chen JG, Zhang MZ, Guo XL, Mu H, Chan AS, Li SR, Yuen ST, Leung SY.

Chin J Dig Dis. 2006;7(4):197-205.

PMID:
17054581
10.

Identification of an MSI-H tumor-specific cytotoxic T cell epitope generated by the (-1) frame of U79260(FTO).

Linnebacher M, Wienck A, Boeck I, Klar E.

J Biomed Biotechnol. 2010;2010:841451. doi: 10.1155/2010/841451. Epub 2010 Mar 18.

11.

A TGF betaRII frameshift-mutation-derived CTL epitope recognised by HLA-A2-restricted CD8+ T cells.

Saeterdal I, Gjertsen MK, Straten P, Eriksen JA, Gaudernack G.

Cancer Immunol Immunother. 2001 Nov;50(9):469-76.

PMID:
11761441
12.

Microsatellite instability in Ewing tumor is not associated with loss of mismatch repair protein expression.

Alldinger I, Schaefer KL, Goedde D, Ottaviano L, Dirksen U, Ranft A, Juergens H, Gabbert HE, Knoefel WT, Poremba C.

J Cancer Res Clin Oncol. 2007 Oct;133(10):749-59. Epub 2007 May 25.

PMID:
17530287
13.

Chk1 frameshift mutation in sporadic and hereditary non-polyposis colorectal cancers with microsatellite instability.

Kim CJ, Lee JH, Song JW, Cho YG, Kim SY, Nam SW, Yoo NJ, Park WS, Lee JY.

Eur J Surg Oncol. 2007 Jun;33(5):580-5. Epub 2007 Apr 3.

PMID:
17408908
14.

Extended microsatellite analysis in microsatellite stable, MSH2 and MLH1 mutation-negative HNPCC patients: genetic reclassification and correlation with clinical features.

Schiemann U, Müller-Koch Y, Gross M, Daum J, Lohse P, Baretton G, Muders M, Mussack T, Kopp R, Holinski-Feder E.

Digestion. 2004;69(3):166-76. Epub 2004 Apr 28.

PMID:
15118395
15.

A ten markers panel provides a more accurate and complete microsatellite instability analysis in mismatch repair-deficient colorectal tumors.

Agostini M, Enzo MV, Morandi L, Bedin C, Pizzini S, Mason S, Bertorelle R, Urso E, Mescoli C, Lise M, Pucciarelli S, Nitti D.

Cancer Biomark. 2010;6(1):49-61. doi: 10.3233/CBM-2009-0118.

PMID:
20164541
16.

Tumor-specific immunological recognition of frameshift-mutated peptides in colon cancer with microsatellite instability.

Ishikawa T, Fujita T, Suzuki Y, Okabe S, Yuasa Y, Iwai T, Kawakami Y.

Cancer Res. 2003 Sep 1;63(17):5564-72.

17.

The mechanisms underlying MMR deficiency in immunodeficiency-related non-Hodgkin lymphomas are different from those in other sporadic microsatellite instable neoplasms.

Borie C, Colas C, Dartigues P, Lazure T, Rince P, Buhard O, Folliot P, Chalastanis A, Muleris M, Hamelin R, Mercier D, Oliveira C, Seruca R, Chadburn A, Leblond V, Barete S, Gaïdano G, Martin A, Gaulard P, Fléjou JF, Raphael M, Duval A.

Int J Cancer. 2009 Nov 15;125(10):2360-6. doi: 10.1002/ijc.24681.

18.

Microsatellite instability is not an uncommon finding in adult de novo acute myeloid leukemia.

Nomdedéu JF, Perea G, Estivill C, Lasa A, Carnicer MJ, Brunet S, Aventín A, Sierra J.

Ann Hematol. 2005 Jun;84(6):368-75. Epub 2005 Mar 24.

PMID:
15789228
19.

Semiallogenic fusions of MSI(+) tumor cells and activated B cells induce MSI-specific T cell responses.

Garbe Y, Klier U, Linnebacher M.

BMC Cancer. 2011 Sep 26;11:410. doi: 10.1186/1471-2407-11-410.

20.

A mononucleotide markers panel to identify hMLH1/hMSH2 germline mutations.

Pedroni M, Roncari B, Maffei S, Losi L, Scarselli A, Di Gregorio C, Marino M, Roncucci L, Benatti P, Ponti G, Rossi G, Menigatti M, Viel A, Genuardi M, de Leon MP.

Dis Markers. 2007;23(3):179-87.

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