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Items: 1 to 20 of 194

1.

Insulin-receptor substrate-2 (irs-2) is required for maintaining glucokinase and glucokinase regulatory protein expression in mouse liver.

Roncero I, Alvarez E, Acosta C, Sanz C, Barrio P, Hurtado-Carneiro V, Burks D, Blázquez E.

PLoS One. 2013;8(4):e58797. doi: 10.1371/journal.pone.0058797. Epub 2013 Apr 1.

2.

Mice mutant for glucokinase regulatory protein exhibit decreased liver glucokinase: a sequestration mechanism in metabolic regulation.

Farrelly D, Brown KS, Tieman A, Ren J, Lira SA, Hagan D, Gregg R, Mookhtiar KA, Hariharan N.

Proc Natl Acad Sci U S A. 1999 Dec 7;96(25):14511-6.

3.

An allosteric activator of glucokinase impairs the interaction of glucokinase and glucokinase regulatory protein and regulates glucose metabolism.

Futamura M, Hosaka H, Kadotani A, Shimazaki H, Sasaki K, Ohyama S, Nishimura T, Eiki J, Nagata Y.

J Biol Chem. 2006 Dec 8;281(49):37668-74. Epub 2006 Oct 6.

4.

Acetylation of glucokinase regulatory protein decreases glucose metabolism by suppressing glucokinase activity.

Park JM, Kim TH, Jo SH, Kim MY, Ahn YH.

Sci Rep. 2015 Dec 1;5:17395. doi: 10.1038/srep17395.

5.

Development of non-insulin-dependent diabetes mellitus in the double knockout mice with disruption of insulin receptor substrate-1 and beta cell glucokinase genes. Genetic reconstitution of diabetes as a polygenic disease.

Terauchi Y, Iwamoto K, Tamemoto H, Komeda K, Ishii C, Kanazawa Y, Asanuma N, Aizawa T, Akanuma Y, Yasuda K, Kodama T, Tobe K, Yazaki Y, Kadowaki T.

J Clin Invest. 1997 Mar 1;99(5):861-6.

6.

Treatment of type 2 diabetes by adenoviral-mediated overexpression of the glucokinase regulatory protein.

Slosberg ED, Desai UJ, Fanelli B, St Denny I, Connelly S, Kaleko M, Boettcher BR, Caplan SL.

Diabetes. 2001 Aug;50(8):1813-20.

7.

Characterization of glucokinase regulatory protein-deficient mice.

Grimsby J, Coffey JW, Dvorozniak MT, Magram J, Li G, Matschinsky FM, Shiota C, Kaur S, Magnuson MA, Grippo JF.

J Biol Chem. 2000 Mar 17;275(11):7826-31.

8.

Glucokinase and glucokinase regulatory proteins are functionally coexpressed before birth in the rat brain.

Roncero I, Sanz C, Alvarez E, Vázquez P, Barrio PA, Blázquez E.

J Neuroendocrinol. 2009 Dec;21(12):973-81. doi: 10.1111/j.1365-2826.2009.01919.x. Epub 2009 Oct 6.

PMID:
19807849
9.

Abnormal regulation of HGP by hyperglycemia in mice with a disrupted glucokinase allele.

Rossetti L, Chen W, Hu M, Hawkins M, Barzilai N, Efrat S.

Am J Physiol. 1997 Oct;273(4 Pt 1):E743-50.

PMID:
9357804
10.

Cell biology assessment of glucokinase mutations V62M and G72R in pancreatic beta-cells: evidence for cellular instability of catalytic activity.

Arden C, Trainer A, de la Iglesia N, Scougall KT, Gloyn AL, Lange AJ, Shaw JA, Matschinsky FM, Agius L.

Diabetes. 2007 Jul;56(7):1773-82. Epub 2007 Mar 27.

11.

Glucokinase regulatory protein is essential for the proper subcellular localisation of liver glucokinase.

de la Iglesia N, Veiga-da-Cunha M, Van Schaftingen E, Guinovart JJ, Ferrer JC.

FEBS Lett. 1999 Aug 6;456(2):332-8.

12.

[Effect of berberine on insulin secretion and glucokinase activity of NIT-1 cells].

Wang ZS, Lu FE, Chen G, Xu LJ, Wang KF, Zou X.

Yao Xue Xue Bao. 2007 Oct;42(10):1045-9. Chinese.

PMID:
18229609
13.

Lack of glucokinase regulatory protein expression may contribute to low glucokinase activity in feline liver.

Hiskett EK, Suwitheechon OU, Lindbloom-Hawley S, Boyle DL, Schermerhorn T.

Vet Res Commun. 2009 Mar;33(3):227-40. doi: 10.1007/s11259-008-9171-6. Epub 2008 Sep 9.

PMID:
18780155
14.

Biochemical basis of glucokinase activation and the regulation by glucokinase regulatory protein in naturally occurring mutations.

Heredia VV, Carlson TJ, Garcia E, Sun S.

J Biol Chem. 2006 Dec 29;281(52):40201-7. Epub 2006 Nov 2.

15.

Biophysical characterization of the interaction between hepatic glucokinase and its regulatory protein: impact of physiological and pharmacological effectors.

Anderka O, Boyken J, Aschenbach U, Batzer A, Boscheinen O, Schmoll D.

J Biol Chem. 2008 Nov 14;283(46):31333-40. doi: 10.1074/jbc.M805434200. Epub 2008 Sep 22.

16.

Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase.

Postic C, Shiota M, Niswender KD, Jetton TL, Chen Y, Moates JM, Shelton KD, Lindner J, Cherrington AD, Magnuson MA.

J Biol Chem. 1999 Jan 1;274(1):305-15.

17.

Molecular basis for the role of glucokinase regulatory protein as the allosteric switch for glucokinase.

Choi JM, Seo MH, Kyeong HH, Kim E, Kim HS.

Proc Natl Acad Sci U S A. 2013 Jun 18;110(25):10171-6. doi: 10.1073/pnas.1300457110. Epub 2013 Jun 3.

18.

Effect of high-fat diet on glucose homeostasis and gene expression in glucokinase knockout mice.

Gorman T, Hope DC, Brownlie R, Yu A, Gill D, Löfvenmark J, Wedin M, Mayers RM, Snaith MR, Smith DM.

Diabetes Obes Metab. 2008 Sep;10(10):885-97. Epub 2007 Nov 22.

PMID:
18034843
19.
20.

Regulation of liver glucokinase activity in rats with fructose-induced insulin resistance and impaired glucose and lipid metabolism.

Francini F, Castro MC, Gagliardino JJ, Massa ML.

Can J Physiol Pharmacol. 2009 Sep;87(9):702-10. doi: 10.1139/y09-064.

PMID:
19794521

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