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Potential of protein phosphatase inhibitor 1 as biomarker of pancreatic β-cell injury in vitro and in vivo.

Jiang L, Brackeva B, Ling Z, Kramer G, Aerts JM, Schuit F, Keymeulen B, Pipeleers D, Gorus F, Martens GA.

Diabetes. 2013 Aug;62(8):2683-8. doi: 10.2337/db12-1507. Epub 2013 Apr 4.


LC-MS/MS identification of doublecortin as abundant beta cell-selective protein discharged by damaged beta cells in vitro.

Jiang L, Brackeva B, Stangé G, Verhaeghen K, Costa O, Couillard-Després S, Rotheneichner P, Aigner L, Van Schravendijk C, Pipeleers D, Ling Z, Gorus F, Martens GA.

J Proteomics. 2013 Mar 27;80:268-80. doi: 10.1016/j.jprot.2012.12.031. Epub 2013 Jan 19.


Potential of UCHL1 as biomarker for destruction of pancreatic beta cells.

Brackeva B, De Punt V, Kramer G, Costa O, Verhaeghen K, Stangé G, Sadones J, Xavier C, Aerts JM, Gorus FK, Martens GA.

J Proteomics. 2015 Mar 18;117:156-67. doi: 10.1016/j.jprot.2015.01.009. Epub 2015 Jan 29.


Plasma GAD65, a Marker for Early β-Cell Loss After Intraportal Islet Cell Transplantation in Diabetic Patients.

Ling Z, De Pauw P, Jacobs-Tulleneers-Thevissen D, Mao R, Gillard P, Hampe CS, Martens GA, In't Veld P, Lernmark Å, Keymeulen B, Gorus F, Pipeleers D.

J Clin Endocrinol Metab. 2015 Jun;100(6):2314-21. doi: 10.1210/jc.2015-1216. Epub 2015 Mar 27.


The orphan nuclear receptor small heterodimer partner negatively regulates pancreatic beta cell survival and hyperglycemia in multiple low-dose streptozotocin-induced type 1 diabetic mice.

Noh JR, Hwang JH, Kim YH, Kim KS, Gang GT, Kim SW, Kim DK, Shong M, Lee IK, Choi HS, Lee CH.

Int J Biochem Cell Biol. 2013 Aug;45(8):1538-45. doi: 10.1016/j.biocel.2013.05.004. Epub 2013 May 13.


Insulin receptor-overexpressing β-cells ameliorate hyperglycemia in diabetic rats through Wnt signaling activation.

Kim MH, Hong SH, Lee MK.

PLoS One. 2013 Jul 9;8(7):e67802. doi: 10.1371/journal.pone.0067802. Print 2013.


Release of glutamate decarboxylase-65 into the circulation by injured pancreatic islet beta-cells.

Waldrop MA, Suckow AT, Marcovina SM, Chessler SD.

Endocrinology. 2007 Oct;148(10):4572-8. Epub 2007 Jun 21.


Beta-cell function and mass in type 2 diabetes.

Larsen MO.

Dan Med Bull. 2009 Aug;56(3):153-64.


Comparative study of regenerative potential of beta cells from young and aged donor mice using a novel islet transplantation model.

Chen X, Zhang X, Chen F, Larson CS, Wang LJ, Kaufman DB.

Transplantation. 2009 Aug 27;88(4):496-503. doi: 10.1097/TP.0b013e3181b0d2ee. Erratum in: Transplantation. 2009 Sep 27;88(6):853.


In vivo conditional Pax4 overexpression in mature islet β-cells prevents stress-induced hyperglycemia in mice.

Hu He KH, Lorenzo PI, Brun T, Jimenez Moreno CM, Aeberhard D, Vallejo Ortega J, Cornu M, Thorel F, Gjinovci A, Thorens B, Herrera PL, Meda P, Wollheim CB, Gauthier BR.

Diabetes. 2011 Jun;60(6):1705-15. doi: 10.2337/db10-1102. Epub 2011 Apr 26.


Glucose-dependent expansion of pancreatic beta-cells by the protein p8 in vitro and in vivo.

Päth G, Opel A, Gehlen M, Rothhammer V, Niu X, Limbert C, Romfeld L, Hügl S, Knoll A, Brendel MD, Bretzel RG, Seufert J.

Am J Physiol Endocrinol Metab. 2006 Dec;291(6):E1168-76. Epub 2006 Jul 5.


GLP-1(28-36) improves β-cell mass and glucose disposal in streptozotocin-induced diabetic mice and activates cAMP/PKA/β-catenin signaling in β-cells in vitro.

Shao W, Wang Z, Ip W, Chiang YT, Xiong X, Chai T, Xu C, Wang Q, Jin T.

Am J Physiol Endocrinol Metab. 2013 Jun 15;304(12):E1263-72. doi: 10.1152/ajpendo.00600.2012. Epub 2013 Apr 9.


Enhanced islet expansion by beta-cell proliferation in young diabetes-prone rats fed a protective diet.

Wang GS, Kauri LM, Patrick C, Bareggi M, Rosenberg L, Scott FW.

J Cell Physiol. 2010 Aug;224(2):501-8. doi: 10.1002/jcp.22151.


Glucose and ATP levels in pancreatic islet tissue of normal and diabetic rats.

Matschinsky FM, Pagliara AS, Stillings SN, Hover BA.

J Clin Invest. 1976 Nov;58(5):1193-200.


Pronounced cytosolic aggregation of cellular prion protein in pancreatic beta-cells in response to hyperglycemia.

Strom A, Wang GS, Reimer R, Finegood DT, Scott FW.

Lab Invest. 2007 Feb;87(2):139-49. Epub 2006 Dec 4.


Immunolocalization of 8-OHdG and OGG1 in pancreatic islets of streptozotocin-induced diabetic rats.

Ku YP, Jin M, Kim KH, Ahn YJ, Yoon SP, You HJ, Chang IY.

Acta Histochem. 2009;111(2):138-44. doi: 10.1016/j.acthis.2008.05.008. Epub 2008 Aug 3.


P21cip-overexpression in the mouse beta cells leads to the improved recovery from streptozotocin-induced diabetes.

Yang J, Zhang W, Jiang W, Sun X, Han Y, Ding M, Shi Y, Deng H.

PLoS One. 2009 Dec 17;4(12):e8344. doi: 10.1371/journal.pone.0008344.


Allogeneic diabetic mesenchymal stem cells transplantation in streptozotocin-induced diabetic rat.

Dong QY, Chen L, Gao GQ, Wang L, Song J, Chen B, Xu YX, Sun L.

Clin Invest Med. 2008 Dec 1;31(6):E328-37.


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